Zu "K04992" wurden 15 Artikel gefunden!
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ML-SA5
Artikelnummer: Cay38326-1
ML-SA5 is an agonist of transient receptor potential mucolipin 1 (TRPML1). It activates whole-endolysosome TRPML1-mediated current (IML1) in isolated vacuoles that were enlarged by vacuolin-1 (Cay-20425) (EC50 = 333 nM). ML-SA5 (3 µM) is cytotoxic to MeWo and M12 melanoma cells but not normal melanocytes. It induces...
| Schlagworte: | Mucolipin Synthetic Agonist 5, N4-[3-chloro-2-(1-piperidinyl)phenyl]-N1,N1-dimethyl-1,4-benzenedisulfonamide |
| Anwendung: | TRPML1 agonist |
| CAS | 2418670-70-7 |
| MW: | 458 D |
ab 40,00 €
ML-SA1
Artikelnummer: Cay29958-10
ML-SA1 is an agonist of transient receptor potential mucolipin 1 (TRPML1). It induces cytosolic calcium increases in HEK293T cells expressing surface-expressed mutant TRPML1 channels when used at a concentration of 10 µM. ML-SA1 activates TRPML1-mediated current (IML1) in isolated vacuoles that were enlarged by...
| Schlagworte: | Mucolipin synthetic agonist 1, 2-[2-(3,4-dihydro-2,2,4-trimethyl-1(2H)-quinolinyl)-2-oxoethyl]-1H-isoindole-1,3(2H)-dione |
| Anwendung: | Mucolipin-1 (TRPML1) agonist |
| CAS | 332382-54-4 |
| MW: | 362.4 D |
ab 60,00 €
Anti-MCOLN1 / TRPML1
Artikelnummer: ARG41330.50
Protein function: Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis. Proposed to play a major role in Ca(2+) release from late endosome and lysosome vesicles to the cytoplasm, which is important for many lysosome-dependent cellular events,...
| Schlagworte: | Anti-ML4, Anti-ML1, Anti-MG-2, Anti-TRPML1, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1, Anti-Transient... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
520,00 €
Anti-MCOLN1
Artikelnummer: ATA-HPA031763.100
Protein function: Nonselective cation channel probably playing a role in the regulation of membrane trafficking events and of metal homeostasis. Proposed to play a major role in Ca(2+) release from late endosome and lysosome vesicles to the cytoplasm, which is important for many lysosome-dependent cellular events,...
| Schlagworte: | Anti-ML1, Anti-ML4, Anti-MG-2, Anti-TRPML1, Anti-MSTP080, Anti-Mucolipin-1, Anti-Mucolipidin, Anti-Transient receptor... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
MCOLN1, Human mucolipin 1, Real Time PCR Primer Set
Artikelnummer: VHPS-5618
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | ML4, MG-2, MCOLN1, MSTP080, Mucolipidin, Mucolipin-1 |
| Anwendung: | RNA quantification |
43,00 €
Mcoln1, Mouse mucolipin 1, Real Time PCR Primer Set
Artikelnummer: VMPS-3766
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Mcoln1, Mucolipin-1, Mucolipidin |
| Anwendung: | RNA quantification |
43,00 €
Anti-MCOLN1, CT (MCOLN1, ML4, Mucolipin-1, MG-2,...
Artikelnummer: 038287.200
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+),...
| Schlagworte: | Anti-ML4, Anti-MG-2, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
728,00 €
Mcoln1, Rat mucolipin 1, Real Time PCR Primer Set
Artikelnummer: VRPS-3575
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Mcoln1, rCG_58948, Mcoln1_predicted, Mucolipin 1 (Predicted), isoform CRA_a |
| Anwendung: | RNA quantification |
52,00 €
Anti-MCOLN1, CT (MCOLN1, ML4, Mucolipin-1, MG-2,...
Artikelnummer: 038287-APC.200
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+),...
| Schlagworte: | Anti-ML4, Anti-MG-2, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1 |
| Anwendung: | FLISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-MCOLN1, CT (MCOLN1, ML4, Mucolipin-1, MG-2,...
Artikelnummer: 038287-Biotin.200
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+),...
| Schlagworte: | Anti-ML4, Anti-MG-2, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-MCOLN1, CT (MCOLN1, ML4, Mucolipin-1, MG-2,...
Artikelnummer: 038287-FITC.200
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+),...
| Schlagworte: | Anti-ML4, Anti-MG-2, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1 |
| Anwendung: | FLISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €
Anti-MCOLN1, CT (MCOLN1, ML4, Mucolipin-1, MG-2,...
Artikelnummer: 038287-HRP.200
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+),...
| Schlagworte: | Anti-ML4, Anti-MG-2, Anti-MCOLN1, Anti-MSTP080, Anti-Mucolipidin, Anti-Mucolipin-1 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
993,00 €