Zu "K04969" wurden 43 Artikel gefunden!
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GSK1702934A
Artikelnummer: Cay34576-1
GSK1702934A is an activator of transient receptor potential canonical 3 (TRPC3) and TRPC6. It induces TRPC3- and TRPC6-dependent currents in whole-cell patch-clamp assays using HEK293 cells expressing the human channels (EC50s = 0.08 and 0.44 µM, respectively). GSK1702934A enhances contractility and induces...
| Schlagworte: | 1,3-dihydro-1-[1-[(5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)carbonyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Anwendung: | TRPC3 / TRPC6 activator |
| CAS | 924377-85-5 |
| MW: | 395.5 D |
ab 49,00 €
SAR7334 (hydrochloride)
Artikelnummer: Cay28292-1
SAR7334 is a transient receptor potential canonical 6 (TRPC6) channel blocker (IC50 = 7.9 nM). It is selective for TRPC6 over TRPC4 and TRPC5 (IC50s = 282 and 226 nM, respectively). SAR7334 (0.2-1 µM) blocks TRPC6-dependent hypoxia-induced vasoconstriction in isolated perfused and ventilated mouse lung. It also...
| Schlagworte: | 4-[[(1R,2R)-2-[(3R)-3-amino-1-piperidinyl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chloro-benzonitrile, dihydrochloride |
| Anwendung: | TRPC6 blocker |
| CAS | 1333207-63-8 |
| MW: | 440.8 D |
ab 56,00 €
Larixyl Acetate
Artikelnummer: Cay35309-5
Larixyl acetate is a diterpenoid that has been found in Larix and has transient receptor potential canonical 6 (TRPC6) inhibitory and analgesic activities. It inhibits the activity of TRPC6 (IC50 = 0.58 µM) and is selective for TRPC6 over TRPC3 (IC50 = 6.83 µM), as well as over nine additional TRP channels at 10 µM....
| Schlagworte: | Larixol Acetate,... |
| Anwendung: | Diterpenoid, TRPC6 inhibitory / analgesic agent |
| CAS | 4608-49-5 |
| MW: | 348.5 D |
ab 54,00 €
Anti-TRPC6 (Transient Receptor Potential Cation Channel...
Artikelnummer: 200-301-B59
Protein function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion,...
| Schlagworte: | Anti-TRP6, Anti-TRP-6, Anti-TRPC6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, chimpanzee |
ab 180,00 €
N-(p-amylcinnamoyl) Anthranilic Acid
Artikelnummer: Cay14531-50
N-(p-amylcinnamoyl) Anthranilic acid (ACA) is a channel blocker that acts on several transient receptor potential (TRP) channels, including TRPM2, TRPM8, and TRPC6 (IC50 = 1.7, 3.8, and 2.3 µM, respectively). It is a weak inhibitor of TRPV1. ACA is also an inhibitor of phospholipase A2, blocking the release of...
| Schlagworte: | ACA, 2-[[1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-benzoic acid |
| Anwendung: | TRP channel blocker |
| CAS | 110683-10-8 |
| MW: | 337.4 D |
ab 93,00 €
Anti-TRPC6
Artikelnummer: ARG51301.100
Protein function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion,...
| Schlagworte: | Anti-Trp6, Anti-TRP-6, Anti-Trpc6, Anti-TrpC6, Anti-Calcium entry channel, Anti-Transient receptor protein 6, Anti-Short... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-TRPC6, C-terminal
Artikelnummer: ARG63815.100
Protein function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion,...
| Schlagworte: | Anti-TRP6, Anti-TRPC6, Anti-TrpC6, Anti-TRP-6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | ELISA, FC |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
871,00 €
Anti-TSC2
Artikelnummer: 600-401-FR1
Anti-TSC2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with TSC2 from other sources has not been determined. Protein function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a...
| Schlagworte: | Anti-TRP6, Anti-TRPC6, Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
848,00 €
Anti-TRPC6
Artikelnummer: NSJ-R30847
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transient receptor potential cation channel, subfamily C, member 6, also known as TRP6, is a transient receptor potentialion channel. Northern blot analysis revealed that TRPC6 is expressed primarily in placenta, lung, spleen, ovary, and small intestine. The...
| Schlagworte: | Anti-TRP-6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential channel 6, TRPC6 Antibody |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-TRPC6
Artikelnummer: NSJ-R32851
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is...
| Schlagworte: | Anti-TRP6, Anti-TRP-6, Anti-TRPC6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
790,00 €
Anti-TRPC6
Artikelnummer: NSJ-R33837-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Transient receptor potential cation channel, subfamily C, member 6 Protein function: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a...
| Schlagworte: | Anti-TRP6, Anti-TRP-6, Anti-TrpC6, Anti-TRPC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-TRPC6
Artikelnummer: E-AB-12914.120
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not...
| Schlagworte: | Anti-TRP6, Anti-TRP-6, Anti-TRPC6, Anti-TrpC6, Anti-Transient receptor protein 6, Anti-Short transient receptor potential... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €