Zu "K04942" wurden 14 Artikel gefunden!
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NEU
ICA
Artikelnummer: Cay45333-1
An inhibitor of KCa2.1/SK1 and KCa2.2/SK2 (IC50 = 43 and 123 nM, respectively, in HEK293 cells expressing the rat channels), prolongs atrial action potential duration and AERP and reduces burst pacing-induced atrial fibrillation in isoprenaline- or carbachol-stimulated isolated rat atrial tissue at 10 µM, active...
| Schlagworte: | N-[4-(2-pyridinyl)-2-thiazolyl]-2-pyridinamine |
| Anwendung: | KCa2.1/SK1 / KCa2.2/SK2 inhibitor |
| CAS | 3374-88-7 |
| MW: | 254.31 D |
ab 93,00 €
GW 542573X
Artikelnummer: Cay43213-1
GW 542573X is an activator of small-conductance calcium-activated potassium channel KCa2.1/SK1. It increases current in an inside-out patch clamp assay using HEK293 cells expressing the human channel (EC50 = 8. µM). GW 542573X is selective for KCa2.1/SK1 over KCa2.2/SK2, KCa2.3/SK3, and intermediate-conductance...
| Schlagworte: | 4-[[[[(2-methoxyphenyl)amino]carbonyl]oxy]methyl]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester |
| Anwendung: | KCa2.1/SK1 activator |
| CAS | 660846-41-3 |
| MW: | 364.44 D |
ab 53,00 €
Anti-KCNN1
Artikelnummer: E-AB-52082.120
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels....
| Schlagworte: | Anti-SK, Anti-SK1, Anti-KCNN1, Anti-SKCa1, Anti-KCa2.1, Anti-SKCa 1, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
SKA-31
Artikelnummer: Cay29690-50
SKA-31 is an activator of the small- and intermediate conductance calcium-activated potassium channels KCa2.1, KCa2.2, KCa2.3, and KCa3.1 (EC50s = 2.9, 1.9, 2.9, and 0.26 µM, respectively, in a patch-clamp assay). It also blocks the voltage-gated potassium (Kv) channels Kv1.3, Kv1.5, Kv3.1, and Kv3.2 by 10 to 30%...
| Schlagworte: | 2-Aminonaphthiazole, naphtho[1,2-d]thiazol-2-amine |
| Anwendung: | KCa2/3 channel activator |
| CAS | 40172-65-4 |
| MW: | 200.3 D |
ab 58,00 €
Anti-KCNN1
Artikelnummer: ATA-HPA065938.100
Protein function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. [The UniProt...
| Schlagworte: | Anti-SK, Anti-SK1, Anti-SKCa1, Anti-KCNN1, Anti-SKCa 1, Anti-KCa2.1, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
KCNN1 (human), recombinant protein
Artikelnummer: ABS-PP-12624-L.100
Protein function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. [The UniProt...
| Schlagworte: | Small conductance calcium-activated potassium channel protein 1, SK1, SKCa 1, SKCa1, KCa2.1, Recombinant Human KCNN1 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 10 kD |
ab 115,00 €
KCNN1, Human potassium intermediate/small conductance...
Artikelnummer: VHPS-4787
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | SK, SK1, SKCa1, KCNN1, KCa2.1, SKCa 1, Small conductance calcium-activated potassium channel protein 1 |
| Anwendung: | RNA quantification |
45,00 €
Kcnn1, Mouse potassium intermediate/small conductance...
Artikelnummer: VMPS-3287
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | SK1, Sk1, SKCa1, Kcnn1, KCa2.1, SKCa 1, Small conductance calcium-activated potassium channel protein 1 |
| Anwendung: | RNA quantification |
45,00 €
Kcnn1, Rat potassium intermediate/small conductance...
Artikelnummer: VRPS-3132
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | SK1, Sk1, SKCa1, Kcnn1, KCa2.1, SKCa 1, Small conductance calcium-activated potassium channel protein 1 |
| Anwendung: | RNA quantification |
54,00 €
Anti-KCNN1, CT (KCNN1, SK, Small conductance...
Artikelnummer: 037343.200
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels....
| Schlagworte: | Anti-SK, Anti-SK1, Anti-SKCa1, Anti-KCNN1, Anti-SKCa 1, Anti-KCa2.1, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
KCNN1 PrEST Antigen
Artikelnummer: ATA-APrEST92611.100
Protein function: Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. [The UniProt...
| Schlagworte: | SK, SK1, SKCa1, KCNN1, SKCa 1, KCa2.1, Small conductance calcium-activated potassium channel protein 1 |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
264,00 €
Anti-KCNN1
Artikelnummer: ELK-ES10262.100
potassium calcium-activated channel subfamily N member 1(KCNN1) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically...
| Schlagworte: | Anti-SK, Anti-SK1, Anti-SKCa1, Anti-KCNN1, Anti-SKCa 1, Anti-KCa2.1, Anti-Small conductance calcium-activated potassium... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 173,00 €