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Zu "K04926" wurden 39 Artikel gefunden!
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Artikelnummer: Cay16674-100
Flupirtine is an activator of voltage-gated potassium channel 7 (Kv7/KCNQ). It induces relaxation of preconstricted pulmonary arteries isolated from wild-type and serotonin transporter-overexpressing (SERT+) mice. Flupirtine (30 mg/kg per day) decreases mean right ventricular pressure and right ventricular...
Schlagworte: | N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid, ethyl ester, 2Z-butenedioate |
Anwendung: | KCNQ agonist, NMDA receptor antagonist |
CAS | 75507-68-5 |
MW: | 420.4 D |
ab 50,00 €
Artikelnummer: Cay15193-5
Potassium (K+) channels are categorized by their mode of activation and the number of transmembrane segments. The voltage-gated six-transmembrane K+ channels include KCNQ1, first recognized for its role in cardiac function and subsequently in hearing, gastrointestinal chloride secretion, and other processes. ML-277...
Schlagworte: | CID-53347902, (2R)-N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide |
Anwendung: | KCNQ1 activator |
CAS | 1401242-74-7 |
MW: | 471.6 D |
ab 60,00 €
Artikelnummer: ARG55375.100
Protein function: Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (PubMed:10646604). Associates with KCNE beta subunits that modulates current kinetics (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505,...
Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
624,00 €
Artikelnummer: ARG64865.100
Protein function: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned...
Schlagworte: | Anti-KCNA8, Anti-KCNQ1, Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated... |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: 200-301-F82
Anti-KCNQ1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with KCNQ1 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with KCNQ1 from other sources has not been determined. Channels and Transporters research....
Schlagworte: | Anti-KCNQ1, Anti-KCNA8, Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated... |
Anwendung: | IHC, IFM, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse, rat |
698,00 €
Artikelnummer: NSJ-R33938-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide.
Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
Anwendung: | WB, IHC (paraffin), ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human, rat |
755,00 €
Artikelnummer: E-AB-15154.120
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward...
Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
Anwendung: | WB, IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: Cay14582-50
The KCNQ potassium channels are neuronal modulators which combine with other KQT or KCNE channels to form heteromultimers. XE 991 is a blocker of KCNQ channels that potently inhibits KCNQ1 and 2 homomeric channels (IC50 = 0.75 and 0.71 µM, respectively) as well as KCNQ2+3 heteromultimers (IC50 = 0.6 µM). It much...
Schlagworte: | 10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone, dihydrochloride |
Anwendung: | KCNQ channel blocker |
CAS | 122955-13-9 |
MW: | 449.4 D |
ab 84,00 €
Artikelnummer: Cay19547-10
Linopirdine is an enhancer of the stimulus-evoked but not basal release of several neurotransmitters, including acetylcholine, dopamine, serotonin, and glutamate. It increases acetylcholine release in rat hippocampal CA1 neurons by blocking voltage-gated, calcium-activated and leak (M-type, Kv7.2/7.3, KCNQ2/3) K+...
Schlagworte: | DuP-996, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)-2H-indol-2-one |
Anwendung: | Nootropic, Cognition enhancer |
CAS | 105431-72-9 |
MW: | 391.5 D |
ab 43,00 €
Artikelnummer: Cay19993-1
Chromanol 293B is a blocker of slowly activating delayed-rectifier K+ current (IKs) with an IC50 value of 6.89 µM in Xenopus oocytes expressing rat IKs channels. It is selective, having no activity at rat Kv1.1 or Kir2.1 channels at a concentration of 30 µM. Chromanol 293B increases the rate and extent of IKs in...
Schlagworte: | Chromanol 239B, rel-N-[(3R,4S)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-methyl-ethanesulfonamide |
Anwendung: | KCNQ1 channel blocker |
CAS | 163163-23-3 |
MW: | 324.4 D |
ab 43,00 €
Artikelnummer: E-AB-60659.120
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward...
Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 198,00 €
Artikelnummer: ARG59538.50
Protein function: Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (PubMed:10646604). Associates with KCNE beta subunits that modulates current kinetics (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505,...
Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
520,00 €