Zu "K04926" wurden 40 Artikel gefunden!
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Anti-KCNQ1
Artikelnummer: ATA-HPA071107.100
Polyclonal Antibody against Human KCNQ1, Gene description: potassium voltage-gated channel subfamily Q member 1, Alternative Gene Names: JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1, Validated applications: ICC, Uniprot ID: P51787, Storage: Store at +4°C for short term storage. Long time storage is recommended at...
| Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
450,00 €
JNJ 303
Artikelnummer: TGM-T7653-100mg
Description: JNJ 303 is a potent blocker of IKs (IC50 : 64 nM). Target: Potassium Channel. Smiles: CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1[C@H]2C[C@H]3C[C@@H]1C[C@](C3)(C2)NS(C)(=O)=O. References: Kang C , Badiceanu A , Brennan J A , et al. beta-adrenergic stimulation augments transmural dispersion of repolarization via...
| Anwendung: | Kv7.1 inhibitor |
| CAS | 878489-28-2 |
| MW: | 440.98 D |
ab 42,00 €
Flupirtine-d4 hydrochloride
Artikelnummer: TGM-T73713-1mg
Description: Flupirtine-d4 (D 9998-d4) hydrochloride, the deuterium-labeled version of Flupirtine (D 9998) hydrochloride, is a selective neuronal potassium channel opener with NMDA receptor antagonist properties [1] [2]. Smiles: Cl.[2H]c1c([2H])c(CNc2ccc(NC(=O)OCC)c(N)n2)c([2H])c([2H])c1F
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, KCNQ agonist, NMDA receptor antagonist |
| CAS | 1324717-75-0 |
| MW: | 344.81 D |
693,00 €
JNJ-303
Artikelnummer: Cay37345-25
JNJ-303 is an inhibitor of voltage-gated potassium channel Kv7.1 (IC50 = 0.064 µM). It is selective for inhibiting Kv7.1 currents (IKs) over INa, IKr, Ito, IK1, and ICaL (IC50s =3.3, 12.6, 11.1, >100, and >10 µM, respectively). It selectively inhibits the heteromeric Kv7.1-KCNE1 complex (IC50 = 0.0784 µM) with no...
| Schlagworte: | 2-(4-chlorophenoxy)-2-methyl-N-[5-[(methylsulfonyl)amino]tricyclo[3.3.1.13,7]dec-2-yl]-propanamide, stereoisomer |
| Anwendung: | Kv7.1 inhibitor |
| CAS | 878489-28-2 |
| MW: | 441 D |
ab 54,00 €
ML277
Artikelnummer: TGM-T3303-100mg
Description: ML277 (CID-53347902) was identified as a potent activator of KCNQ1 channels (EC(50)=260 nM). Target: Potassium Channel. Smiles: COc1ccc(cc1)-c1csc(NC(=O)[C@H]2CCCCN2S(=O)(=O)c2ccc(C)cc2)n1. References: Mattmann ME, Yu H, Lin Z, et al. Identification of...
| Schlagworte: | CID-53347902, ML-277 |
| Anwendung: | KCNQ1 activator |
| CAS | 1401242-74-7 |
| MW: | 471.59 D |
ab 34,00 €
Anti-KCNQ1
Artikelnummer: CSB-PA237012.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KCNQ1. Antigen Species: Human
| Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-KCNQ1
Artikelnummer: CSB-PA942745.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: KCNQ1. Antigen Species: Human
| Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Potassium voltage-gated channel subfamily KQT member 1...
Artikelnummer: CSB-CF012087HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 1-676aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MAAASSPPRA ERKRWGWGRL PGARRGSAGL AKKCPFSLEL AEGGPAGGAL YAPIAPGAPG PAPPASPAAP AAPPVASDLG PRPPVSLDPR VSIYSTRRPV LARTHVQGRV...
| Schlagworte: | KQT-like 1, Voltage-gated potassium channel subunit Kv7.1, Potassium voltage-gated channel subfamily KQT member 1, IKs... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 80.7 kD |
ab 1.458,00 €
Flupirtine (maleate)
Artikelnummer: Cay16674-100
Flupirtine is an activator of voltage-gated potassium channel 7 (Kv7/KCNQ). It induces relaxation of preconstricted pulmonary arteries isolated from wild-type and serotonin transporter-overexpressing (SERT+) mice. Flupirtine (30 mg/kg per day) decreases mean right ventricular pressure and right ventricular...
| Schlagworte: | N-[2-amino-6-[[(4-fluorophenyl)methyl]amino]-3-pyridinyl]-carbamic acid, ethyl ester, 2Z-butenedioate |
| Anwendung: | KCNQ agonist, NMDA receptor antagonist |
| CAS | 75507-68-5 |
| MW: | 420.4 D |
ab 52,00 €
ML-277
Artikelnummer: Cay15193-5
Potassium (K+) channels are categorized by their mode of activation and the number of transmembrane segments. The voltage-gated six-transmembrane K+ channels include KCNQ1, first recognized for its role in cardiac function and subsequently in hearing, gastrointestinal chloride secretion, and other processes. ML-277...
| Schlagworte: | CID-53347902, (2R)-N-[4-(4-methoxyphenyl)-2-thiazolyl]-1-[(4-methylphenyl)sulfonyl]-2-piperidinecarboxamide |
| Anwendung: | KCNQ1 activator |
| CAS | 1401242-74-7 |
| MW: | 471.6 D |
ab 61,00 €
Anti-KCNQ1
Artikelnummer: ARG55375.100
Protein function: Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon (PubMed:10646604). Associates with KCNE beta subunits that modulates current kinetics (PubMed:9312006, PubMed:9108097, PubMed:8900283, PubMed:10646604, PubMed:11101505,...
| Schlagworte: | Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated channel subfamily KQT... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
Anti-KCNQ1, C-terminal
Artikelnummer: ARG64865.100
Protein function: Probably important in cardiac repolarization. Associates with KCNE1 (MinK) to form the I(Ks) cardiac potassium current. Elicits a rapidly activating, potassium-selective outward current. Muscarinic agonist oxotremorine-M strongly suppresses KCNQ1/KCNE1 current in CHO cells in which cloned...
| Schlagworte: | Anti-KCNA8, Anti-KCNQ1, Anti-KQT-like 1, Anti-Voltage-gated potassium channel subunit Kv7.1, Anti-Potassium voltage-gated... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €