Zu "K04876" wurden 29 Artikel gefunden!
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BAPTA AM
Artikelnummer: Cay15551-10
BAPTA (Cay-11706) is membrane-impermeable calcium chelator that binds extracellular calcium ions (Kd = 0.11 µM), with selectivity over magnesium ions or protons. BAPTA and its derivatives can also be used as calcium indicators, since the absorption maximum for BAPTA changes when it is complexed with calcium...
| Schlagworte: | BAPTA Acetoxymethyl ester,... |
| Anwendung: | Cell permeable calcium chelator |
| CAS | 126150-97-8 |
| MW: | 764.7 D |
ab 57,00 €
Psora 4
Artikelnummer: Cay28389-1
Psora 4 is an inhibitor of voltage-gated potassium channels (Kv1.3, EC50 = 3 nM). It is selective for Kv1.3 over Kv1.1, Kv1.2, Kv1.4, Kv1.7, and Kv3.1 channels (EC50s = 62, 49, 202, 100, and 1,500 nM, respectively) but does inhibit the Kv1.5 channel (EC50 = 7.7 nM). Psora 4 selectively binds to the C-type...
| Schlagworte: | 4-(4-phenylbutoxy)-7H-furo[3,2-g ][1]benzopyran-7-one |
| Anwendung: | Voltage-gated potassium channel Kv1.3 inhibitor |
| CAS | 724709-68-6 |
| MW: | 334.4 D |
ab 49,00 €
4',7-Di-O-methylnaringenin
Artikelnummer: Cay36190-1
4',7-Di-O-methylnaringenin is a flavonoid aglycone that has been found in Vitex quinata and has potassium channel inhibitory and anticancer activities. It inhibits the voltage-gated potassium channel subtype Kv1.3 in a patch-clamp assay when used at a concentration of 30 µM. 4',7-Di-O-methylnaringenin is cytotoxic...
| Schlagworte: | Naringenin 4',7-dimethyl ether, 2S,3-dihydro-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | Flavonoid aglycone, potassium channel inhibitor, anticancer agent |
| MW: | 300.3 D |
ab 84,00 €
Anti-Kv1.3, clone S23-27
Artikelnummer: 200-301-F93
Anti-Kv1.3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.3 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.3 from other sources has not been determined. Ion Channels research. Protein...
| Schlagworte: | Anti-HGK5, Anti-HLK3, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K() channel HuKIII, Anti-Voltage-gated potassium channel... |
| Anwendung: | IHC, IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
752,00 €
Anti-KCNA3 / Kv1.3
Artikelnummer: NSJ-R32012
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member...
| Schlagworte: | Anti-HGK5, Anti-HLK3, Anti-KCNA3, Anti-HPCN3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-KCNA3
Artikelnummer: ATA-HPA016625.100
Protein function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their...
| Schlagworte: | Anti-HGK5, Anti-HLK3, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
PAP-1
Artikelnummer: Cay30105-1
PAP-1 is an inhibitor of Kv1.3 voltage-gated potassium channels (EC50 = 2 nM at -80 mV in cells overexpressing the human channel). It is selective for Kv1.3 over a panel of 22 ion channels, including potassium, sodium, calcium, and chloride channels (EC50s = 45-15,000 nM for all). PAP-1 inhibits anti-CD3...
| Schlagworte: | 5-(4-Phenoxybutoxy)psoralen, 4-(4-phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one |
| Anwendung: | Kv1.3 channels inhibitor |
| CAS | 870653-45-5 |
| MW: | 350.4 D |
ab 60,00 €
Anti-Kv1.3
Artikelnummer: ELK-EA308.50
N/A Protein function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their...
| Schlagworte: | Anti-HLK3, Anti-HGK5, Anti-KCNA3, Anti-HPCN3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
173,00 €
CP 339,818 (hydrochloride)
Artikelnummer: Cay40766-10
CP 339,818 is an inhibitor of voltage-gated potassium channel Kv1.3 and Kv1.4 (IC50s = 0.23 and 0.3 µM, respectively). It is selective for these channels over Kv1.1, Kv1.2, Kv1.5, and Kv1.6 channels (IC50s = 62, 14, 19, and 20 µM, respectively), as well as Kv3.1, Kv3.2, Kv3.4, and Kv4.2 channels (IC50s = 17, 10, 36,...
| Schlagworte: | N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine, monohydrochloride |
| Anwendung: | Kv1.3 / Kv1.4 inhibitor |
| CAS | 478341-55-8 |
| MW: | 340.9 D |
ab 79,00 €
Anti-KCNA3
Artikelnummer: CSB-PA003118.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-HLK3, Anti-HGK5, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
BAPTA-AM
Artikelnummer: TGM-T6245-10mg
Description: BAPTA-AM is a calcium chelator that is cell-permeable and selective, blocking hERG, hKv1.3, and hKv1.5 channels (IC50=1.3/1.45/1.23 µM). BAPTA-AM has a 105-fold higher affinity for Ca2+ than for Mg2+, and can be used for the role of calcium in cell signaling. Target: Potassium Channel. Smiles:...
| Schlagworte: | BAPTA/AM |
| Anwendung: | Cell permeable calcium chelator |
| CAS | 126150-97-8 |
| MW: | 764.68 D |
ab 30,00 €
PAP-1
Artikelnummer: TGM-TQ0179-100mg
Description: PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a selective, orally active Kv1.3 blocker with an EC50 of 2 nM. Target: Potassium Channel. Smiles: O=c1ccc2c(OCCCCOc3ccccc3)c3ccoc3cc2o1. References: Schmitz A, et al. Design of PAP-1, a selective small molecule Kv1.3 blocker, for the suppression of effector memory...
| Schlagworte: | 5-(4-Phenoxybutoxy)psoralen |
| Anwendung: | Kv1.3 channels inhibitor |
| CAS | 870653-45-5 |
| MW: | 350.36 D |
ab 54,00 €