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BAPTA AM
BAPTA AM

Artikelnummer: Cay15551-10

BAPTA (Cay-11706) is membrane-impermeable calcium chelator that binds extracellular calcium ions (Kd = 0.11 µM), with selectivity over magnesium ions or protons. BAPTA and its derivatives can also be used as calcium indicators, since the absorption maximum for BAPTA changes when it is complexed with calcium...
Schlagworte: BAPTA Acetoxymethyl ester,...
Anwendung: Cell permeable calcium chelator
CAS 126150-97-8
MW: 764.7 D
ab 59,00 €
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Psora 4
Psora 4

Artikelnummer: Cay28389-1

Psora 4 is an inhibitor of voltage-gated potassium channels (Kv1.3, EC50 = 3 nM). It is selective for Kv1.3 over Kv1.1, Kv1.2, Kv1.4, Kv1.7, and Kv3.1 channels (EC50s = 62, 49, 202, 100, and 1,500 nM, respectively) but does inhibit the Kv1.5 channel (EC50 = 7.7 nM). Psora 4 selectively binds to the C-type...
Schlagworte: 4-(4-phenylbutoxy)-7H-furo[3,2-g ][1]benzopyran-7-one
Anwendung: Voltage-gated potassium channel Kv1.3 inhibitor
CAS 724709-68-6
MW: 334.4 D
ab 51,00 €
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4',7-Di-O-methylnaringenin
4',7-Di-O-methylnaringenin

Artikelnummer: Cay36190-1

4',7-Di-O-methylnaringenin is a flavonoid aglycone that has been found in Vitex quinata and has potassium channel inhibitory and anticancer activities. It inhibits the voltage-gated potassium channel subtype Kv1.3 in a patch-clamp assay when used at a concentration of 30 µM. 4',7-Di-O-methylnaringenin is cytotoxic...
Schlagworte: Naringenin 4',7-dimethyl ether, 2S,3-dihydro-5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Anwendung: Flavonoid aglycone, potassium channel inhibitor, anticancer agent
MW: 300.3 D
ab 87,00 €
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Anti-Kv1.3, clone S23-27
Anti-Kv1.3, clone S23-27

Artikelnummer: 200-301-F93

Anti-Kv1.3 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Kv1.3 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Kv1.3 from other sources has not been determined. Ion Channels research. Protein...
Schlagworte: Anti-HGK5, Anti-HLK3, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K() channel HuKIII, Anti-Voltage-gated potassium channel...
Anwendung: IHC, IFM, WB
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
752,00 €
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Anti-KCNA3 / Kv1.3
Anti-KCNA3 / Kv1.3

Artikelnummer: NSJ-R32012

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member...
Schlagworte: Anti-HGK5, Anti-HLK3, Anti-KCNA3, Anti-HPCN3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
790,00 €
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Anti-KCNA3
Anti-KCNA3

Artikelnummer: ATA-HPA016625.100

Protein function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their...
Schlagworte: Anti-HGK5, Anti-HLK3, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 330,00 €
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PAP-1
PAP-1

Artikelnummer: Cay30105-1

PAP-1 is an inhibitor of Kv1.3 voltage-gated potassium channels (EC50 = 2 nM at -80 mV in cells overexpressing the human channel). It is selective for Kv1.3 over a panel of 22 ion channels, including potassium, sodium, calcium, and chloride channels (EC50s = 45-15,000 nM for all). PAP-1 inhibits anti-CD3...
Schlagworte: 5-(4-Phenoxybutoxy)psoralen, 4-(4-phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one
Anwendung: Kv1.3 channels inhibitor
CAS 870653-45-5
MW: 350.4 D
ab 62,00 €
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Anti-Kv1.3
Anti-Kv1.3

Artikelnummer: ELK-EA308.50

N/A Protein function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their...
Schlagworte: Anti-HLK3, Anti-HGK5, Anti-KCNA3, Anti-HPCN3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
173,00 €
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CP 339,818 (hydrochloride)
CP 339,818 (hydrochloride)

Artikelnummer: Cay40766-10

CP 339,818 is an inhibitor of voltage-gated potassium channel Kv1.3 and Kv1.4 (IC50s = 0.23 and 0.3 µM, respectively). It is selective for these channels over Kv1.1, Kv1.2, Kv1.5, and Kv1.6 channels (IC50s = 62, 14, 19, and 20 µM, respectively), as well as Kv3.1, Kv3.2, Kv3.4, and Kv4.2 channels (IC50s = 17, 10, 36,...
Schlagworte: N-[1-(phenylmethyl)-4(1H)-quinolinylidene]-1-pentanamine, monohydrochloride
Anwendung: Kv1.3 / Kv1.4 inhibitor
CAS 478341-55-8
MW: 340.9 D
ab 82,00 €
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Anti-KCNA3
Anti-KCNA3

Artikelnummer: CSB-PA003118.100

Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: Anti-HLK3, Anti-HGK5, Anti-HPCN3, Anti-KCNA3, Anti-Voltage-gated K(+) channel HuKIII, Anti-Voltage-gated potassium channel...
Anwendung: ELISA, WB, IHC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 126,00 €
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CP 339818 hydrochloride
CP 339818 hydrochloride

Artikelnummer: TGM-T22684-100mg

Description: KV1.3 channel antagonist. Target: Others. Smiles: Cl.N(=C1C=CN(C=2C=CC=CC12)CC=3C=CC=CC3)CCCCC
Anwendung: Kv1.3 / Kv1.4 inhibitor
CAS 478341-55-8
MW: 340.89 D
ab 1.440,00 €
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Psora 4
Psora 4

Artikelnummer: TGM-T21819-1mg

Description: Psora-4 is a potent and selective inhibitor of K_v 1.3 (voltage-gated potassium channels) with a Hill coefficient of 2 and an EC50 value of 3 nM [1]. It exhibits immunosuppressive activity and inhibits the proliferation of human and rat myelin-specific effector memory T cells in vitro [2]. Target:...
Anwendung: Voltage-gated potassium channel Kv1.3 inhibitor
CAS 724709-68-6
MW: 334.37 D
ab 225,00 €
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