Zu "K04857" wurden 31 Artikel gefunden!
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Pinaverium bromide
Artikelnummer: TGM-T7603-100mg
Description: Pinaverium bromide is an calcium channel blocker with Antispasmodic and effectively relieves pain, diarrhea and intestinal discomfort. Target: Calcium Channel. Smiles: COc1cc(Br)c(C[N+]2(CCOCCC3CCC4CC3C4(C)C)CCOCC2)cc1OC.[Br-]. References: Action of Pinaverium Bromide, a Calcium-Antagonist, on...
| Anwendung: | Targets voltage-dependent calcium channel L type alpha-1S (CACNA1S, CAV1.1) |
| CAS | 53251-94-8 |
| MW: | 591.42 D |
ab 31,00 €
Nifedipine
Artikelnummer: Cay11106-5
Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 µM. Nifedipine (1 µM) reduces TGF-beta-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse...
| Schlagworte: | BAY 1040, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3,5-dimethyl ester |
| Anwendung: | Dihydropyridine calcium channel blocker |
| CAS | 21829-25-4 |
| MW: | 346.3 D |
ab 28,00 €
Bepridil (hydrochloride)
Artikelnummer: Cay19645-5
Bepridil is a dihydropyridine that has anti-anginal and anti-arrhythmic actions by blocking calcium channels in heart and smooth muscle. It is recognized as a non-selective channel blocker, altering myocardial Ca2+, Na+, and K+ currents. For example, it blocks voltage-gated Ca2+ (Cav3.2) and K+ (hERG and KCNQ4)...
| Schlagworte: | beta-[(2-methylpropoxy)methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine, monohydrochloride |
| Anwendung: | Calcium channel blocker |
| CAS | 68099-86-5 |
| MW: | 403 D |
ab 44,00 €
Benidipine (hydrochloride)
Artikelnummer: Cay21607-50
Benidipine is an orally bioavailable blocker of L-, T-, and N-type calcium channels. In guinea pig ventricular cells benidipine has an IC50 of 2.7 nM for calcium currents, determined using whole cell voltage clamp electrophysiology. It prevents oxidative stress dose-dependently in vitro, decreases blood pressure in...
| Schlagworte: | (±)-Benidipine, KW-3049, (4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl... |
| Anwendung: | Calcium channel blocker |
| CAS | 91599-74-5 |
| MW: | 542 D |
ab 52,00 €
Amlodipine
Artikelnummer: LKT-A5045.1
Almost white crystalline powder. A calcium channel antagonist with potent antioxidant activity. It inhibits doxorubicin-induced myocyte apoptosis by supressing the mitochondrial apoptotic pathway.It has been found to inhibit hyperplasia and hypertrophy in mesangial cells.
| Schlagworte: | UK-48340 |
| Anwendung: | Ca channel antagonist |
| CAS | 88150-42-9 |
| MW: | 408,88 D |
ab 141,00 €
Lercanidipine (hydrochloride)
Artikelnummer: Cay29104-50
Lercanidipine is a dihydropyridine L-type calcium channel blocker. It binds to rat brain and heart homogenates (Kis = 0.24-0.3 and 0.22 nM, respectively, in radioligand binding assays) and inhibits potassium-induced contraction of isolated rat aorta (IC50 = 1.3 nM). Lercanidipine reduces diastolic blood pressure...
| Schlagworte: | 3,5-pyridinedicarboxylic acid,... |
| Anwendung: | L-type calcium channel blocker |
| CAS | 132866-11-6 |
| MW: | 648.2 D |
ab 53,00 €
Nilvadipine
Artikelnummer: Cay21243-5
Nilvadipine is a dihydropyridine L-type calcium channel blocker. It is selective for L-type over N-, P/Q-, and R-type calcium channels at 10 µM. Nilvadipine (10 mg/kg per day, p.o.) inhibits increases in systolic blood pressure induced by chronic intravenous infusion of the peptide vasoconstrictor endothelin in...
| Schlagworte: | (±)-Nilvadipine, CL 287,389, FK-235, FR34235, SKF 102362,... |
| Anwendung: | Calcium channel L-type blocker |
| CAS | 75530-68-6 |
| MW: | 385.4 D |
ab 44,00 €
Benidipine Hydrochloride
Artikelnummer: LKT-B1752.10
Calcium channel blocker.
| Schlagworte: | KW-3049 |
| Anwendung: | Calcium channel L type blocker |
| CAS | 91599-74-5 |
| MW: | 542.03 D |
ab 66,00 €
Lercanidipine Hydrochloride
Artikelnummer: LKT-L1869.50
Calcium channel blocker.
| Anwendung: | L-type calcium channel blocker |
| CAS | 132866-11-6 |
| MW: | 648.2 D |
ab 95,00 €
Nitrendipine
Artikelnummer: LKT-N3478.25
Calcium channel blocker.
| Anwendung: | Calcium channel L type blocker |
| CAS | 39562-70-4 |
| MW: | 360.37 D |
ab 95,00 €
Nemadipine A
Artikelnummer: Cay21689-50
Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel alpha1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick ciliary neurons....
| Schlagworte: | 1,4-dihydro-2,6-dimethyl-4-(2,3,4,5,6-pentafluorophenyl)-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester |
| Anwendung: | Cell-permeable L-type calcium channel protein inhibitor |
| CAS | 54280-71-6 |
| MW: | 419.3 D |
ab 94,00 €
Azelnidipine
Artikelnummer: LKT-A9617.10
Dihydropyridine, L-type Ca2+ channel blocker.
| Anwendung: | Calcium channel L type blocker |
| CAS | 123524-52-7 |
| MW: | 582.66 D |
ab 73,00 €