Zu "K04850" wurden 88 Artikel gefunden!
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Darodipine
Artikelnummer: Cay41667-10
Darodipine is a calcium channel inhibitor. It selectively inhibits calcium-induced contractions of isolated rabbit aorta (pD2 = 8.8) over norepinephrine-, serotonin-, or angiotensin II-induced contractions at 10 µM. In vivo, continuous infusion of darodipine (2 µg/kg per minute) increases cerebral tissue oxygenation...
| Schlagworte: | PY 108-068, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester |
| Anwendung: | Calcium channel inhibitor |
| CAS | 72803-02-2 |
| MW: | 371.4 D |
ab 75,00 €
Bepridil hydrochloride
Artikelnummer: TGM-T5391-100mg
Description: Bepridil hydrochloride (CERM 1978) is a calcium channel blocker that also inhibits Na+/Ca2+ exchange (NCX), sodium channels, and cardiac sarcolemmal KATP channels. Target: Calcium Channel. Smiles: Cl.CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1. References: Flaim SF, et al. Effects of bepridil hydrochloride...
| Schlagworte: | CERM 1978 |
| Anwendung: | Calcium channel blocker |
| CAS | 68099-86-5 |
| MW: | 403 D |
ab 42,00 €
CACNA1C Protein, Guinea Pig, Recombinant (His)
Artikelnummer: TGM-TMPH-00780-100ug
Description: Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required...
| Schlagworte: | Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, CCHL1A1, Voltage-gated calcium channel subunit... |
| MW: | 22.3 kD |
ab 1.709,00 €
Amlodipine-d4 Maleate (Racemic)
Artikelnummer: TGM-TMIH-0087-1mg
Description: Amlodipine-d4 Maleate (Racemic) is a deuterated compound of Amlodipine Maleate (Racemic). Amlodipine Maleate (Racemic) has a CAS number of 88150-47-4. Amlodipine maleate is an orally active dihydropyridine calcium channel blocker that inhibits calcium inward flow by blocking voltage-dependent L-type...
| Anwendung: | Internal standard, GC-MS, LC-MS |
| CAS | 1185246-15-4 |
| MW: | 528.97 D |
128,00 €
Nimodipine-d7
Artikelnummer: TGM-TMIJ-0095-1mg
Description: Nimodipine-d7 is a deuterated compound of Nimodipine. Nimodipine has a CAS number of 66085-59-4. Nimodipine, a 1, 4-dihydropyridine calcium channel blocker, acts primarily on vascular smooth muscle cells. Smiles:...
| Anwendung: | GC-MS, LC-MS, internal standard, Ca2+ channel antagonist |
| CAS | 1246815-36-0 |
| MW: | 425.48 D |
Bitte fragen Sie den aktuellen Preis für diesen Artikel an.
Felodipine-d5
Artikelnummer: TGM-TMIJ-0140-1mg
Description: Felodipine-d5 is a deuterated compound of Felodipine. Felodipine has a CAS number of 72509-76-3. Felodipine is a longlasting 1, 4-dihydropyridine calcium channel repressor. Smiles: C1C(C2C(C(=O)OC)=C(C)NC(C)=C2C(=O)OC([2H])([2H])C([2H])([2H])[2H])=C(Cl)C(Cl)=CC=1
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, L-type calcium channel inhibitor |
| CAS | 1242281-38-4 |
| MW: | 389.29 D |
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Manidipine
Artikelnummer: TGM-T6577-100mg
Description: Manidipine (Iperten), a calcium channel blocker, which is dihydropyridine type. It is utilized. Target: Calcium Channel. Smiles: C(OCCN1CCN(C(C2=CC=CC=C2)C3=CC=CC=C3)CC1)(=O)C=4C(C(C(OC)=O)=C(C)NC4C)C5=CC(N(=O)=O)=CC=C5. References: Roth M, et al. Proc Natl Acad Sci U S A, 1992, 89(9), 4071-4075.
| Schlagworte: | Franidipine, Iperten, Artedil |
| Anwendung: | L-type / T-type calcium channel blocker |
| CAS | 89226-50-6 |
| MW: | 610.7 D |
ab 40,00 €
Nifedipine
Artikelnummer: Cay11106-1
Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 µM. Nifedipine (1 µM) reduces TGF-beta-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse...
| Schlagworte: | BAY 1040, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3,5-dimethyl ester |
| Anwendung: | Dihydropyridine calcium channel blocker |
| CAS | 21829-25-4 |
| MW: | 346.3 D |
ab 28,00 €
Verapamil (hydrochloride)
Artikelnummer: Cay14288-1
Verapamil is the prototypical blocker of L-type calcium channels that produces excitation-contraction uncoupling in cardiac muscle by preventing the slow-inward current of calcium ions. Verapamil can also block calcium fluxes in vascular smooth muscle. It has both peripheral and coronary vasodilator effects (IC50 =...
| Schlagworte: | NSC 272366, NSC 657799,... |
| Anwendung: | L-type Calcium channel blocker |
| CAS | 152-11-4 |
| MW: | 491.1 D |
40,00 €
Nifedipine-d6
Artikelnummer: TGM-T12222-10mg
Description: Nifedipine D6 is deuterium labeled nifedipine which is a potent blocker of calcium channel. Smiles: [2H]C([2H])([2H])OC(=O)C1=C(C)NC(C)=C(C1c1ccccc1[N+]([O-])=O)C(=O)OC([2H])([2H])[2H]. References: Patel DP, et al. Highly sensitive and rapid ultra-performance liquid chromatography-tandem mass...
| Schlagworte: | BAY-a-1040 D6, Nifedipine D6 |
| Anwendung: | Dihydropyridine calcium channel blocker, GC-MS, LC-MS, internal standard |
| CAS | 1188266-14-9 |
| MW: | 352.37 D |
ab 178,00 €
Carboxyamidotriazole
Artikelnummer: TGM-T14872-10mg
Description: Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. It shows anti-inflammatory, anti-tumor, and antiangiogenic effects. Target: Calcium Channel. Smiles: NC(=O)c1nnn(Cc2cc(Cl)c(C(=O)c3ccc(Cl)cc3)c(Cl)c2)c1N. References:...
| Schlagworte: | L-651582, CAI |
| Anwendung: | Non-selective calcium channel blocker |
| CAS | 99519-84-3 |
| MW: | 424.67 D |
ab 264,00 €
Nemadipine-A
Artikelnummer: TGM-T35729-10mg
Description: Nemadipine A is an L-type calcium channel blocker that induces morphological and growth defects in wild-type C. elegans and those with hypoexpression of egl-19, which encodes the only L-type calcium channel alpha1-subunit in the C. elegans genome. It also inhibits L-type calcium channels in chick...
| Anwendung: | Cell-permeable L-type calcium channel protein inhibitor |
| CAS | 54280-71-6 |
| MW: | 419.34 D |
ab 170,00 €