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Zu "K04819" wurden 79 Artikel gefunden!
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Artikelnummer: Cay14999-5
Ondansetron (hydrochloride hydrate) (Cay-14999) is an analytical reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal...
Schlagworte: | 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate |
Anwendung: | Analytical reference material, Serotonin 5-HT3 receptor antagonist, Antiemetic |
CAS | 103639-04-9 |
MW: | 365.9 D |
84,00 €
Artikelnummer: Cay21239-100
Granisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 3.9 nM) with antiemetic activity. It is selective for 5-HT3 over 5-HT4 receptors (Ki = >1,000 nM). Granisetron (0.3, 1, and 3 mg/kg, p.o.) increases the latency to first vomiting episode and reduces the number of vomiting episodes in a...
Schlagworte: | BRL 43694, 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide, monohydrochloride |
Anwendung: | 5-HT3 receptor antagonist |
CAS | 107007-99-8 |
MW: | 348.9 D |
ab 77,00 €
Artikelnummer: Cay21710-1
Ondansetron (hydrochloride) (CRM) (Cay-21710) is a certified reference material categorized as an antiemetic. Formulations containing ondansetron have been used to reduce alcohol consumption and mood disturbances in early-onset alcoholics. This product is intended for research and forensic applications.Formal Name:...
Schlagworte: | GR 38032F, NSC 665799, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one, monohydrochloride |
Anwendung: | Certified reference material, antiemetic, 5-HT3-receptor antagonist |
CAS | 99614-02-5 |
MW: | 329.8 D |
158,00 €
Artikelnummer: Cay23694-5
Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...
Schlagworte: | 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-piperazine, monohydrobromide |
Anwendung: | Serotonergic agent |
CAS | 960203-27-4 |
MW: | 379.4 D |
ab 44,00 €
Artikelnummer: Cay22434-25
Alosetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Kis = 0.3 and 0.4 nM for the rat cortical and human recombinant receptors, respectively). It is selective for 5-HT3 over 5-HT2 and 5-HT1A receptors (Kis = 6.3 and >100 µM, respectively), as well as alpha1-, beta1-, and beta2- adrenergic, M1,...
Schlagworte: | GR 68755, 2,3,4,5-tetrahydro-5-methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-1H-pyrido[4,3-b]indol-1-one, monohydrochloride |
Anwendung: | Serotonin 5-HT3 receptor antagonist |
CAS | 122852-69-1 |
MW: | 330.8 D |
ab 32,00 €
Artikelnummer: Cay15548-10
Ramosetron is a potent and selective antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.06 nM). It has little or no effect at other 5-HT receptor subtypes or at adrenergic or histamine receptors. Ramosetron competitively blocks serotonin-mediated contraction of the colon. It has applications in...
Schlagworte: | (1-methyl-1H-indol-3-yl)[(6R)-4,5,6,7-tetrahydro-1H-benzimidazol-6-yl]-methanone, monohydrochloride |
Anwendung: | 5-HT3 receptor antagonist |
CAS | 132907-72-3 |
MW: | 315.8 D |
ab 92,00 €
Artikelnummer: Cay21240-50
Tropisetron is an antagonist of the serotonin (5-HT) receptor subtype 5-HT3 (Ki = 0.8 nM for the mouse receptor). It is selective for 5-HT3 over the 5-HT4 receptor subtype (Ki = 156 nM for the porcine receptor). Tropisetron is also an antagonist of the alpha9 nicotinic acetylcholine receptor (nAChR, IC50 = 166 nM...
Schlagworte: | ICS 205-930, SDZ-ICS 930, 1H-indole-3-carboxylic acid (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, monohydrochloride |
Anwendung: | 5-HT3 receptor antagonist |
CAS | 105826-92-4 |
MW: | 320.8 D |
ab 43,00 €
Artikelnummer: Cay30183-10
Vortioxetine is a multimodal serotonergic agent that acts as a serotonin (5-HT, Cay-14332) reuptake inhibitor (Ki = 1.6 nM) and binds to the 5-HT1A, 5-HT1B, 5-HT3A, and 5-HT7 receptors (Kis = 15, 33, 3.7, and 19 nM, respectively). It also binds to the beta1-adrenergic receptor (Ki = 46 nM). It acts as an antagonist...
Schlagworte: | 1-[2-[(2,4-dimethylphenyl)thio]phenyl]-piperazine |
Anwendung: | Serotonin receptor antagonist |
CAS | 508233-74-7 |
MW: | 298.4 D |
ab 50,00 €
Artikelnummer: ARG64018.100
Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a...
Schlagworte: | Anti-HTR3A, Anti-5HT3R, Anti-5-HT3A, Anti-5-HT3R, Anti-5-HT-3, Anti-5-HT3-A, Anti-Serotonin receptor 3A,... |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human, rat |
784,00 €
Artikelnummer: ARG64960.100
Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but...
Schlagworte: | Anti-HTR3B, Anti-5-HT3B, Anti-5-HT3-B, Anti-Serotonin receptor 3B, Anti-5-hydroxytryptamine receptor 3B |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: 200-401-I12
Anti-Serotonin Receptor 3A Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-Serotonin Receptor 3A from human, mouse, and rat based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-Serotonin Receptor 3A from other sources has...
Schlagworte: | Anti-Htr3a, Anti-5HT3 receptor |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
756,00 €
Artikelnummer: NSJ-R34121-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 5-HT3A, 5-HT3R, HTR3A Protein function: This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone,...
Schlagworte: | Anti-5HT3R, Anti-HTR3A, Anti-5-HT3R, Anti-5-HT3A, Anti-5-HT-3, Anti-5-HT3-A, Anti-Serotonin receptor 3A,... |
Anwendung: | WB, ICC, IF, ELISA (peptide), IHC (paraffin) |
Wirt: | Goat |
Spezies-Reaktivität: | human, rat |
755,00 €