Zu "K04809" wurden 57 Artikel gefunden!
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Anti-CHRNA7
Artikelnummer: ATA-HPA054017.100
Rabbit Polyclonal CHRNA7 Antibody against Human cholinergic receptor nicotinic alpha 7 subunit. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000030525:...
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
(±)-Anatoxin A (fumarate)
Artikelnummer: Cay14609-1
(±)-Anatoxin A is a bicyclic amine isolated from the blue-green alga A. aquae that displays high affinity for nicotinic acetylcholine receptors (Kd = 0.1-0.2 µM). It binds alpha4beta2- and alpha7-type nicotinic receptors with Ki values of 1.3 nM and 1.8 µM, respectively, and stimulates [3H]-dopamine release from...
| Schlagworte: | 1-(9-azabicyclo[4.2.1]non-2-en-2-yl)-ethanone, 2-butenedioate |
| Anwendung: | Neuronal nicotinic acetylcholine receptor agonist |
| CAS | 1219922-30-1 |
| MW: | 281.3 D |
363,00 €
A-582941
Artikelnummer: Cay42375-10
An agonist of a7 nAChRs, induces inward currents in Xenopus oocytes expressing the rat or human receptor (EC50s = 2.45 and 4.26 µM, respectively), which can be reversed by methyllycaconitine, selectively binds to a7 nAChRs (Kis = 10.8 and 16.7 nM for the rat and human receptors, respectively) over a panel of >75...
| Schlagworte: | octahydro-2-methyl-5-(6-phenyl-3-pyridazinyl)-pyrrolo[3,4-c]pyrrole, dihydrochloride |
| Anwendung: | A7 nAChRs agonist |
| CAS | 848591-90-2 |
| MW: | 353.29 D |
ab 118,00 €
PHA-543613
Artikelnummer: Cay42222-10
An agonist of alpha7 nAChRs, selective for alpha7 nAChRs over alpha4beta2-, alpha4beta4-, alpha3beta2-, or alpha3beta4 subunit-containing nAChRs and 5-HT3 (EC50s = 0.03, >100, >50, >100, >100, and 11 µM, respectively, in calcium mobilization assays), prevents decreases in the number of retinal ganglion cells in a...
| Schlagworte: | PHA-543,613, N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-furo[2,3-c]pyridine-5-carboxamide |
| Anwendung: | alpha7 nAChR agonist |
| CAS | 478149-53-0 |
| MW: | 271.31 D |
ab 186,00 €
DMAB-anabaseine (hydrochloride)
Artikelnummer: Cay42562-1
DMAB-anabaseine is a partial agonist of alpha7 nicotinic acetylcholine receptors (nAChRs). It induces currents in a whole-cell patch-clamp assay using Xenopus oocytes expressing human alpha7 nAChRs (EC50 = 21 µM). Intracerebroventricular administration of DMAB-anabaseine (80 µg/animal) inhibits nicotine-induced...
| Schlagworte: | 4-[(5,6-dihydro[2,3'-bipyridin]-3(4H)-ylidene)methyl]-N,N-dimethyl-benzenamine, dihydrochloride |
| Anwendung: | Nicotinic acetylcholine receptor alpha-7 partial agonist |
| CAS | 154149-38-9 |
| MW: | 364.31 D |
ab 147,00 €
GTS-21 (hydrochloride)
Artikelnummer: Cay21570-50
GTS-21 is an agonist of alpha7-containing nicotinic acetylcholine receptors (nAChRs) that, at a concentration of 100 µM, activates human alpha7-containing nAChRs expressed in Xenopus oocytes to 60% of the levels generated by endogenous ligand acetylcholine. It is selective for alpha7-containing nAChRs, having no...
| Schlagworte: | DMXB-A, (3E)-3-[(2,4-dimethoxyphenyl)methylene]-3,4,5,6-tetrahydro-2,3'-bipyridine, dihydrochloride |
| Anwendung: | Partial alpha7 nicotinic acetylcholine receptor agonist |
| CAS | 156223-05-1 |
| MW: | 381.3 D |
ab 96,00 €
Methyllycaconitine (citrate)
Artikelnummer: Cay21398-25
Methyllycaconitine (MLA) is an antagonist of alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs, Ki = 1.4 nM). It is less effective at other nAChRs. MLA is used to selectively evaluate the role of alpha7-containing nAChRs in signaling pathways.Formal Name:...
| Schlagworte: | MLA,... |
| Anwendung: | nAChR (CHRNA7) antagonist |
| CAS | 351344-10-0 |
| MW: | 874.9 D |
ab 52,00 €
(±)-Nornicotine
Artikelnummer: Cay20505-250
(±)-Nornicotine is an active metabolite of nicotine (Cay-16535) and a nicotinic acetylcholine receptor (nAChR) agonist. It induces currents in Xenopus oocytes expressing human alpha7 nAChRs or alpha6 subunit-containing nAChRs (EC50s = 17 and 3.7 µM, respectively). (±)-Nornicotine promotes cell migration and...
| Schlagworte: | (R,S)-Nornicotine, DL-Nornicotine, 3-(2-pyrrolidinyl)-pyridine |
| Anwendung: | nAChR agonist |
| CAS | 5746-86-1 |
| MW: | 148.2 D |
ab 56,00 €
NS 1738
Artikelnummer: Cay21018-5
NS 1738 is a positive allosteric modulator of the alpha7-containing neuronal nicotinic acetylcholine receptors (nAChRs). When applied in the presence of ACh, NS 1738 increases the peak amplitude of the current flowing through alpha7-containing nAChRs (EC50 = 3.4 µM). NS 1738 displays no substantial activity for...
| Schlagworte: | NSC 213859, N-(5-chloro-2-hydroxyphenyl)-N'-[2-chloro-5-(trifluoromethyl)phenyl]-urea |
| Anwendung: | Positive allosteric nAChR (CHRNA7) modulator |
| CAS | 501684-93-1 |
| MW: | 365.1 D |
ab 49,00 €
CCMI
Artikelnummer: Cay37571-25
CCMI is a positive allosteric modulator (PAM) of alpha7 nicotinic acetylcholine receptors (nAChRs). It enhances ACh-, nicotine-, or choline-induced currents in Xenopus oocytes expressing recombinant human alpha7 nAChRs (EC50s = 0.7, 0.6, and 0.5 µM, respectively). In vivo, CCMI (0.3 and 1 mg/kg, i.v.) improves...
| Schlagworte: | AVL-3288, XY-4083, N-(4-chlorophenyl)-alpha-[[(4-chlorophenyl)amino]methylene]-3-methyl-5-isoxazoleacetamide |
| Anwendung: | Alpha7 nAChR positive allosteric modulator |
| CAS | 917837-54-8 |
| MW: | 388.3 D |
ab 40,00 €
Anti-CHRNA7
Artikelnummer: NSJ-R34630-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cholinergic receptor, nicotinic, alpha 7 Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of...
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7, CHRNA7 Antibody |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Anti-CHRFAM7A
Artikelnummer: E-AB-12583.120
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a...
| Schlagworte: | Anti-CHRNA7, Anti-NACHRA7, Anti-Neuronal acetylcholine receptor subunit alpha-7, CHRFAM7A Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €