Zu "K04804" wurden 23 Artikel gefunden!
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Rivanicline (hydrochloride)
Artikelnummer: Cay42184-1
An a4ß2 subunit-containing nAChR agonist, selectively induces rubidium ion efflux in M10 cells expressing a4ß2 subunit-containing nAChRs (EC50 = 0.73 µM for the chicken channels) over M10 cells expressing a3ß4- or a1ß1?d subunit-containing receptors (EC50s = >1,000 nM for both for the chicken channels) and a panel...
| Schlagworte: | RJR-2403, trans-Metanicotine, (E)-N-methyl-4-(pyridin-3-yl)but-3-en-1- amine, hydrochloride |
| Anwendung: | alpha4beta2 subunit-containing nAChR agonist |
| MW: | 162.23 D |
ab 53,00 €
(±)-Nicotine-d3
Artikelnummer: Cay18256-25
(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine (Cay-16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for...
| Schlagworte: | (±)-Nicotine-methyl-d3, DL-Nicotine-d3, 3-[1-(methyl-d3)-2-pyrrolidinyl]-pyridine |
| Anwendung: | nAChR agonist, internal control |
| CAS | 69980-24-1 |
| MW: | 165.3 D |
ab 56,00 €
Chlorisondamine (iodide)
Artikelnummer: Cay20119-1
Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....
| Schlagworte: | 4,5,6,7-tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-1H-isoindolium, diiodide |
| Anwendung: | Nicotinic acetylcholine receptor antagonist |
| CAS | 96750-66-2 |
| MW: | 611.9 D |
ab 56,00 €
Cisatracurium (besylate)
Artikelnummer: Cay22959-100
Cisatracurium is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs) and non-depolarizing muscle relaxant. It inhibits stimulation of human adult muscle nAChRs by acetylcholine (Cay-23829) with an IC50 value of 10 nM. It also inhibits mouse nAChRs with IC50 values of 54 and 115 nM for adult and...
| Schlagworte: | (1R,1'R,2R,2'R)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydr... |
| Anwendung: | nAChR competitive antagonist |
| CAS | 96946-42-8 |
| MW: | 1243.5 D |
ab 139,00 €
Hexamethonium (bromide)
Artikelnummer: Cay25505-100
Hexamethonium is a peripherally-acting nondepolarizing neuromuscular blocking agent that acts as an antagonist of nicotinic acetylcholine receptors (nAChRs). It decreases acetylcholine release induced by carbamoylcholine (Cay-14486) in isolated cat superior cervical ganglion when used at concentrations of 27.4 and...
| Schlagworte: | N1,N1,N1,N6,N6,N6-hexamethyl-1,6-hexanediaminium, dibromide |
| Anwendung: | Peripherally-acting muscle relaxant, nicotinic acetylcholine receptor antagonist |
| CAS | 55-97-0 |
| MW: | 362.2 D |
ab 38,00 €
Anti-CHRNA2
Artikelnummer: CSB-PA168970.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human
| Schlagworte: | Anti-CHRNA2, Anti-Neuronal acetylcholine receptor subunit alpha-2, ACHA2_HUMAN antibody, AChR antibody, Cholinergic... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-CHRNA2
Artikelnummer: CSB-PA279534.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CHRNA2. Antigen Species: Human
| Schlagworte: | Anti-CHRNA2, Anti-Neuronal acetylcholine receptor subunit alpha-2, ACHA2_HUMAN antibody, AChR antibody, Cholinergic... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-CHRNA2
Artikelnummer: ATA-HPA048348.100
Polyclonal Antibody against Human CHRNA2, Gene description: cholinergic receptor nicotinic alpha 2 subunit, Validated applications: ICC, Uniprot ID: Q15822, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C. Protein function: After binding acetylcholine, the AChR responds by an...
| Schlagworte: | Anti-CHRNA2, Anti-Neuronal acetylcholine receptor subunit alpha-2 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
NEU
Rat CHRNA2 (Neuronal Acetylcholine Receptor Subunit...
Artikelnummer: G-AEKE03105.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CHRNA2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CHRNA2. Next,...
| Schlagworte: | Chrna2, Neuronal acetylcholine receptor subunit alpha-2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
694,00 €
Rat CHRNA2(Neuronal Acetylcholine Receptor Subunit...
Artikelnummer: ELK-ELK0108.48
Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous...
| Schlagworte: | Chrna2, Neuronal acetylcholine receptor subunit alpha-2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
Nanodisc Human ACHA2-Strep Protein
Artikelnummer: G-HDFP1408.10
Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [The UniProt Consortium]
| Schlagworte: | CHRNA2, Neuronal acetylcholine receptor subunit alpha-2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.605,00 €
Nanodisc Human ACHA2 Protein
Artikelnummer: G-HDFP693.10
Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [The UniProt Consortium]
| Schlagworte: | CHRNA2, Neuronal acetylcholine receptor subunit alpha-2 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.693,00 €