Zu "K04803" wurden 66 Artikel gefunden!
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Vecuronium Bromide
Artikelnummer: LKT-V1810.10
A nonpolarizing neuromuscular relaxant.
| Schlagworte: | NC-45, Org-NC-45 |
| Anwendung: | Muscle-type nicotinic cholinergic receptor antagonist |
| CAS | 50700-72-6 |
| MW: | 637,74 D |
ab 128,00 €
(±)-Nicotine-d3
Artikelnummer: Cay18256-10
(±)-Nicotine-d3 is intended for use as an internal standard for the quantification of (±)-nicotine (Cay-16535) by GC- or LC-MS. (±)-Nicotine is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (nAChRs, Kis = 481 and 11.1 nM for...
| Schlagworte: | (±)-Nicotine-methyl-d3, DL-Nicotine-d3, 3-[1-(methyl-d3)-2-pyrrolidinyl]-pyridine |
| Anwendung: | nAChR agonist, internal control |
| CAS | 69980-24-1 |
| MW: | 165.3 D |
ab 56,00 €
Rocuronium (bromide)
Artikelnummer: Cay23698-10
Rocuronium is a non-depolarizing muscle relaxant. It selectively induces neuromuscular blockade in cats (ED50s = 153, 185, 1,329, and 4,119 µg/kg for tibialis, soleus, and vagus muscles, and nictitating membranes, respectively) with a more rapid onset time than vecuronium (Cay-15603). Formulations containing...
| Schlagworte: | (+)-Rocuronium,... |
| Anwendung: | Muscarinic acetylcholine receptor antagonist |
| CAS | 119302-91-9 |
| MW: | 609.7 D |
ab 49,00 €
Pancuronium (bromide hydrate)
Artikelnummer: Cay23778-10
Pancuronium is an aminosteroid antagonist of muscle-type nicotinic acetylcholine receptors (nAChRs) with an IC50 value of 14.8 nM using patch clamp electrophysiology in BOSC23 cells expressing mouse nAChRs. It acts as a non-depolarizing neuromuscular blocking agent. Pancuronium enhances anesthesia induced by...
| Schlagworte: | NSC 293162, 1,1'-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)androstane-2,16-diyl]bis[1-methyl-piperidinium],... |
| Anwendung: | Nicotinic cholinergic receptor antagonist |
| MW: | 732.7 D |
ab 49,00 €
Atracurium (besylate)
Artikelnummer: Cay17796-10
Atracurium (besylate) is a benzylisoquinoline that acts as a neuromuscular blocking agent with slow onset and intermediate duration. It causes non-depolarizing block of the neuromuscular junction.Formal Name:...
| Schlagworte: | BW 33A, Tracrium, Wellcome 33A74,... |
| Anwendung: | Neuromuscular blocking agent, muscle-type nicotinic cholinergic receptor antagonist |
| CAS | 64228-81-5 |
| MW: | 1243.5 D |
ab 49,00 €
TMB 8 (hydrochloride)
Artikelnummer: Cay23928-5
TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and alpha3beta4 subunit-containing ganglionic nAChRs expressed in TE671/RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain...
| Schlagworte: | 3,4,5-trimethoxy-benzoic acid, 8-(diethylamino)octyl ester, monohydrochloride |
| Anwendung: | Nicotinic acetylcholine receptor non-competitive antagonist |
| CAS | 53464-72-5 |
| MW: | 432 D |
ab 42,00 €
Anti-AChR (nicotinic)
Artikelnummer: NSJ-R30303
0.5mg/ml if reconstituted with 0.2ml sterile DI water. AChR alpha, also called CHRNA, is mapped on 2q24-q32. This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha...
| Schlagworte: | Anti-ACHRA, Anti-CHRNA1, Anti-Acetylcholine receptor subunit alpha, AChR Antibody (nicotinic) |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Chlorisondamine (iodide)
Artikelnummer: Cay20119-10
Chlorisondamine is an antagonist of nicotinic acetylcholine receptors (nAChRs, IC50 = 1.8 µM in rat striatal synaptosomes) and a ganglion blocker. It decreases dopamine release induced by nicotine (Cay-16535, Cay-20887) in a dose-dependent manner in rat striatal synaptosomes at concentrations ranging from 0-100 µM....
| Schlagworte: | 4,5,6,7-tetrachloro-2,3-dihydro-2-methyl-2-[2-(trimethylammonio)ethyl]-1H-isoindolium, diiodide |
| Anwendung: | Nicotinic acetylcholine receptor antagonist |
| CAS | 96750-66-2 |
| MW: | 611.9 D |
ab 56,00 €
Mivacurium (chloride)
Artikelnummer: Cay23610-10
Mivacurium is an antagonist of nicotinic acetylcholine receptors (nAChRs) and muscarinic M2 and M3 receptors (ED50s = 0.08, 0.3, and 0.1 mg/kg for ex vivo human skeletal muscle nAChRs, guinea pig cardiac M2 receptors, and guinea pig bronchial M3 receptors, respectively). It inhibits acetylcholine-induced activation...
| Schlagworte: | (1R,1'R)-2,2'-[[(4E)-1,8-dioxo-4-octene-1,8-diyl]bis(oxy-3,1-propanediyl)]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-... |
| Anwendung: | Neuromuscular blocking agent |
| CAS | 106861-44-3 |
| MW: | 1100.2 D |
ab 49,00 €
Rocuronium Bromide
Artikelnummer: LKT-R5611.25
An aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anesthesia to facilitate endotraceal intubation.
| Schlagworte: | Neuromuscular blocking agent |
| Anwendung: | Muscle-type nicotinic cholinergic receptor antagonist |
| CAS | 119302-91-9 |
| MW: | 609,68 D |
ab 100,00 €
Anti-CHRNA1 / Nicotinic Acetylcholine R alpha 1
Artikelnummer: ARG58430.50
Protein function: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. [The UniProt Consortium]
| Schlagworte: | Anti-acetyl-ACHRA, Anti-acetyl-CHRNA1, Anti-acetyl-Acetylcholine receptor subunit alpha |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
551,00 €
Succinylcholine (chloride hydrate)
Artikelnummer: Cay32829-10
Succinylcholine is an agonist of muscle-type nicotinic acetylcholine receptors (nAChRs). It activates the muscle-type alpha1beta1deltaepsilon subunit-containing nAChR (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor) then induces desensitization of the receptor. It is selective for the muscle-type...
| Schlagworte: | Suxamethonium, 2,2'-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-ethanaminium, dichloride, dihydrate |
| Anwendung: | Muscle relaxant, nAChR agonist |
| CAS | 6101-15-1 |
| MW: | 397.3 D |
ab 49,00 €