Zu "K04734" wurden 130 Artikel gefunden!
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Anti-Recombinant Phospho-IkappaB-alpha (Ser36), clone 9B2
Artikelnummer: E-AN301280L.100
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear...
| Schlagworte: | Anti-NFKBIA, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant IkB alpha, clone A419
Artikelnummer: E-AN301711L.100
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses.
| Schlagworte: | Anti-NFKBIA, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-Recombinant Phospho-IkappaB-alpha (Ser32), clone 9D8
Artikelnummer: E-AN301182L.100
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear...
| Schlagworte: | Anti-NFKBIA, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha, Anti-Major histocompatibility complex enhancer-binding... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
IkappaBalpha (20-39) (human) (trifluoroacetate salt)
Artikelnummer: Cay44044-1
IkappaBalpha (20-39) is a peptide fragment of the N-terminal signal-receiving domain of IkappaBalpha (Cay-43691), which is an inhibitor of NF-kappaB and a member of the IkappaB family of proteins. It contains several post-translational modification sites that regulate IkappaBalpha activity, including the...
| Schlagworte: | NFKBIA, NF-kappaB Inhibitor alpha |
| Anwendung: | I-kappa-B-alpha peptide fragment |
| MW: | 2371.66 D |
ab 112,00 €
IkappaBalpha (human, recombinant)
Artikelnummer: Cay43691-50
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the...
| Schlagworte: | IKBA, NFKBIA, IkB-alpha, IkappaBalpha, I-kappa-B-alpha, NF-kappa-B inhibitor alpha, Major histocompatibility complex... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
560,00 €
BAY 11-7082
Artikelnummer: Cay10010266-5
The transcription factor NF-kappaB plays a key role in regulating over 150 target genes including the expression of inflammatory cytokines, chemokines, immunoreceptors, and cell adhesion molecules. In the cytoplasm, inactive NF-kappaB complexes are bound to an inhibitor IkappaB. However in response to certain...
| Schlagworte: | 3-[(4-methylphenyl)sulfonyl]-(2E)-propenenitrile |
| Anwendung: | NF-kappaB activation inhibitor |
| CAS | 19542-67-7 |
| MW: | 207.3 D |
ab 73,00 €
BAY 11-7085
Artikelnummer: Cay14795-5
In the classical pathway of NF-kappaB activation, phosphorylation of the inhibitor of NF-kappaB (IkappaBalpha) releases the inhibitor from NF-kappaB, allowing IkappaBalpha degradation and NF-kappaB activation and nuclear import. BAY 11-7085 is an irreversible inhibitor of IkappaBalpha phosphorylation, preventing...
| Schlagworte: | 3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2E-propenenitrile |
| Anwendung: | Irreversible IkappaBalpha phosphorylation inhibitor |
| CAS | 196309-76-9 |
| MW: | 249.3 D |
ab 85,00 €
BAY 11-7082
Artikelnummer: AG-CR1-0013-M010
IkappaBalpha kinase inhibitor, NF-kappaB inhibitor, Potential anti-inflammatory agent, Apoptosis inducer, Inhibits the release of proinflammatory cytokines, Inflammasome inhibitor Inhibits platelet aggregation.
| Schlagworte: | (E)-3-(4-Methylphenylsulfonyl)-2-propenenenitrile |
| Anwendung: | NFkappaB inhibitor |
| CAS | 19542-67-7 |
| MW: | 207,3 D |
ab 66,00 €
Anti-IkappaBalpha, CT (IkBa)
Artikelnummer: 100-4167C
Protein function: Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the...
| Schlagworte: | Anti-IKBA, Anti-NFKBIA, Anti-IkB-alpha, Anti-IkappaBalpha, Anti-I-kappa-B-alpha, Anti-NF-kappa-B inhibitor alpha,... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
Tetra-O-methylscutellarein
Artikelnummer: CDX-M0514-M005
Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta (IKKalpha/beta) and Inhibitory-kappa-B-alpha (IkappaBalpha), inhibiting p65 translocation and thereby...
| Schlagworte: | Scutellarein tetramethyl ether, 5-Methoxysalvigenin, 4',5,6,7-Tetramethoxyflavone, NSC53908 |
| Anwendung: | Antiinflammatory agent |
| CAS | 1168-42-9 |
| MW: | 342.3 D |
ab 183,00 €
Ro 106-9920
Artikelnummer: Cay15373-1
Transcriptional activation by NF-kappaB is limited by IkappaBalpha binding, which masks the NF-kappaB nuclear localization signal that initiates nuclear translocation. Cytokines trigger a signaling cascade of kinases that target IkappaBalpha for degradation, enabling NF-kappaB to promote gene expression. Because...
| Schlagworte: | 6-(phenylsulfinyl)-tetrazolo[1,5-b]pyridazine |
| Anwendung: | IkappaBalpha ubiquitination inhibitor |
| CAS | 62645-28-7 |
| MW: | 245.3 D |
ab 73,00 €
BAY 11-7082
Artikelnummer: LKT-B030966.5
inhibits inflammatory signaling
| Schlagworte: | 3-[(4-methylphenyl)sulfonyl]-(2E)-propenenitrile |
| Anwendung: | NF-kappaB activation inhibitor |
| CAS | 19542-67-7 |
| MW: | 207.25 D |
ab 83,00 €