Zu "K04730" wurden 68 Artikel gefunden!
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Anti-Recombinant IRAK1, clone A567
Artikelnummer: E-AN301855L.100
IRAK1 is the first member of the death domain containing protein kinase family that play a key role in initiating innate immune response against foreign pathogens. They are involved in Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling pathways. Upon ligand binding to TLR/IL-1R, IRAK1 is recruited...
| Schlagworte: | Anti-IRAK1, Anti-Interleukin-1 receptor-associated kinase 1, Recombinant IRAK1 Monoclonal Antibody |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-IRAK1
Artikelnummer: ATA-HPA049920.100
Rabbit Polyclonal IRAK1 Antibody against Human interleukin 1 receptor associated kinase 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000031392: 87%,...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
JH-X-119-01
Artikelnummer: Cay43041-5
JH-X-119-01 is a covalent inhibitor of IL-1 receptor-associated kinase 1 (IRAK1, IC50 = 9 nM). It is selective for IRAK1 over IRAK4 (IC50 = >10,000 nM). JH-X-119-01 is cytotoxic against a panel of mutant MyD88-expressing Waldenstrom's macroglobulinemia (WM), ABC subtype diffuse large B cell lymphoma (DLBCL), and...
| Schlagworte: | N-[4-[[3-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]phenyl]-6-(1H-pyrazol-3-yl)-2-pyridinecarboxamide |
| Anwendung: | Covalent IRAK1 inhibitor |
| CAS | 2227368-54-7 |
| MW: | 452.47 D |
ab 134,00 €
Anti-IRAK-1
Artikelnummer: Cay13843-1
Nuclear factor-kappaB (NF-kappaB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappaB mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF-alpha, and LPS. A...
| Schlagworte: | Interleukin-1 Receptor-Associated Kinase 1 |
| Anwendung: | IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
463,00 €
Anti-IRAK1
Artikelnummer: A303-743A-T
Protein function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor- signaling complex upon TLR activation. Association with MYD88...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
IRAK-1/4 Inhibitor
Artikelnummer: Cay17540-1
Interleukin-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of Toll/IL-1 receptor (TIR) family members. Dysregulation of TIR signaling, typified by increased NF-kappaB activity, results in the development of some cancers and other diseases, making the development of IRAK...
| Schlagworte: | N-[1-[2-(4-morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitro-benzamide |
| Anwendung: | IRAK1 inhibitor, IRAK4 inhibitor |
| CAS | 509093-47-4 |
| MW: | 395.4 D |
ab 49,00 €
Anti-IRAK
Artikelnummer: ARG57418.50
Protein function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor- signaling complex upon TLR activation. Association with MYD88...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
559,00 €
Anti-IRAK1
Artikelnummer: A303-744A
Protein function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor- signaling complex upon TLR activation. Association with MYD88...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
IRAK1, His-tag
Artikelnummer: BPS-40202
Human interleukin-1 receptor-associated kinase 1 (IRAK1), GenBank Accession No. NM_001569, a.a 186-530, with N-terminal His-tag, MW = 40 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | IRAK, IRAK-1, EC=2.7.11.1, Interleukin-1 receptor-associated kinase 1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 40 kD |
551,00 €
Human IRAK1 / Interleukin-1 receptor-associated kinase 1...
Artikelnummer: G-HUFI01479.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
![Anti-IRAK, clone [8F1A7]](https://www.biomol.com/media/image/71/e3/21/200-301-BZ2_200x200.jpg "Anti-IRAK, clone [8F1A7]")
Anti-IRAK, clone [8F1A7]
Artikelnummer: 200-301-BZ2
Anti-IRAK Monoclonal Antibody was Protein A purified from monospecific antiserum by immunoaffinity purification. Cross reactivity with IRAK [8F1A7] from other sources has not been determined. Protein function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
992,00 €
Anti-IRAK (IL-1 Receptor-associated Kinase)
Artikelnummer: 200-401-951
Protein function: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor- signaling complex upon TLR activation. Association with MYD88...
| Schlagworte: | Anti-IRAK, Anti-IRAK1, Anti-IRAK-1, EC=2.7.11.1, Anti-Interleukin-1 receptor-associated kinase 1 |
| Anwendung: | ELISA, IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
848,00 €