Zu "K04728" wurden 117 Artikel gefunden!
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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Artikelnummer: 200-301-400
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
| Anwendung: | ELISA, FC, IHC, IFM, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 180,00 €
Anti-ATM / ATM serine / threonine kinase, clone ATM/9472
Artikelnummer: NEO-472-MSM2-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm, Cytoplasmic vesicle, Nucleus. Chromosome Location: 11q22.3. Protein Function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as...
| Schlagworte: | Anti-ATM, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated, 559 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €
Anti-ATM / ATM serine / threonine kinase, clone ATM/9472
Artikelnummer: NEO-472-MSM2-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm, Cytoplasmic vesicle, Nucleus. Chromosome Location: 11q22.3. Protein Function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as...
| Schlagworte: | Anti-ATM, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated, 559 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-Recombinant ATM, clone 3P12
Artikelnummer: E-AN300613L.100
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates, thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint...
| Schlagworte: | Anti-ATM, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated, Recombinant ATM Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-phospho-ATM Protein Kinase (Ser1981), clone 7C10D8
Artikelnummer: 200-301-500
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
| Anwendung: | ELISA, FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
812,00 €
Anti-ATM Protein Kinase
Artikelnummer: 600-401-398
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-ATM, Anti-A-T mutated, EC=2.7.11.1, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
733,00 €
Anti-ATM
Artikelnummer: A300-136A
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated |
| Anwendung: | WB, IP |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
ab 165,00 €
Ku-55933
Artikelnummer: Cay16336-1
Ku-55933 is a potent ATP-competitive inhibitor of the ataxia-telangiectasia mutated (ATM) kinase (IC50 = 13 nM, Ki = 2.2 nM). Inhibition of ATM by Ku-55933 blocks radiation-induced phosphorylation of downstream cellular targets and sensitizes cells to the cytotoxic effects of both ionizing radiation and...
| Schlagworte: | ATM Kinase Inhibitor, 2-(4-morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one |
| Anwendung: | Potent ATP-competitive ATM kinase inhibitor |
| CAS | 587871-26-9 |
| MW: | 395.5 D |
ab 44,00 €
Anti-ATM
Artikelnummer: A300-299A
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
586,00 €
Anti-phospho-ATM Protein Kinase (Ser1981)
Artikelnummer: 600-601-400S
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia... |
| Anwendung: | ELISA, WB |
| Wirt: | Sheep |
| Spezies-Reaktivität: | human |
ab 180,00 €
Ku-60019
Artikelnummer: Cay17502-1
Ataxia-telangiectasia mutated (ATM) is a serine/threonine kinase that activates checkpoint signaling following double strand DNA breaks and genotoxic stress. Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50 = 6.3 nM), blocking the phosphorylation of ATM substrate proteins. It is much less effective or...
| Schlagworte: | rel-2R,6S-dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-4-morpholineacetamide |
| Anwendung: | ATM kinase inhibitor |
| CAS | 925701-46-8 |
| MW: | 547.7 D |
ab 45,00 €
Anti-ATM
Artikelnummer: A300-135A
Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
| Schlagworte: | Anti-ATM, Anti-A-T mutated, EC=2.7.11.1, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated |
| Anwendung: | WB, IP |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
ab 165,00 €