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Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12
Anti-phospho-ATM Protein Kinase (Ser1981), clone 10H11.E12

Artikelnummer: 200-301-400

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia...
Anwendung: ELISA, FC, IHC, IFM, WB
Wirt: Mouse
Spezies-Reaktivität: human, mouse, rat
ab 180,00 €
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Anti-ATM
Anti-ATM

Artikelnummer: A300-299A-T

Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA...
Schlagworte: Anti-ATM, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
164,00 €
Bewerten
-10 %
Rabattaktion
Human ATM (Ataxia Telangiectasia Mutated) ELISA Kit
Human ATM (Ataxia Telangiectasia Mutated) ELISA Kit

Artikelnummer: ELK-ELK1896.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ATM. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ATM. Next,...
Schlagworte: ATM, A-T mutated, Serine-protein kinase ATM, Ataxia telangiectasia mutated
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
Bewerten
-10 %
Rabattaktion
Mouse ATM (Ataxia Telangiectasia Mutated) ELISA Kit
Mouse ATM (Ataxia Telangiectasia Mutated) ELISA Kit

Artikelnummer: ELK-ELK4506.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ATM. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ATM. Next,...
Schlagworte: Atm, A-T mutated homolog, Serine-protein kinase ATM, Ataxia telangiectasia mutated homolog
Anwendung: ELISA
Spezies-Reaktivität: mouse
365,00 € ab 328,50 €
Bewerten
-10 %
Rabattaktion
Anti-ATM
Anti-ATM

Artikelnummer: ELK-EA323.100

Ataxia telangiectasia mutated kinase (ATM) is a serine/threonine kinase that regulates cell cycle checkpoints and DNA repair. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair. Protein function: Serine/threonine protein kinase which activates checkpoint...
Schlagworte: Anti-ATM, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated, ATM Rabbit pAb
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
283,00 € 254,70 €
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A011
A011

Artikelnummer: Cay39183-1

A011 is an inhibitor of ataxia-telangiectasia mutated (ATM) kinase (IC50 = 1 nM). It is selective for ATM over a panel of 408 additional kinases at 10 µM. A011 inhibits the growth of SW620 and HCT116 colorectal cancer cells (IC50s = 0.14 and 0.91 µM, respectively) and enhances cell death induced by DNA topoisomerase...
Schlagworte: (R)-N,N-dimethyl-3-((5-(1-(1-phenylethyl)-1H-[1,2,3]triazolo[4,5-c]quinolin-8-yl)pyridin-2-yl)oxy)propan-1-amine
Anwendung: ATM kinase inhibitor
MW: 452.6 D
ab 77,00 €
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Anti-phospho-ATM Protein  Kinase (Ser1981), clone  7C10D8
Anti-phospho-ATM Protein Kinase (Ser1981), clone 7C10D8

Artikelnummer: 200-301-500

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-phospho-ATM, Anti-phospho-A-T mutated, EC=2.7.11.1, Anti-phospho-Serine-protein kinase ATM, Anti-phospho-Ataxia...
Anwendung: ELISA, FC, IHC, WB
Wirt: Mouse
Spezies-Reaktivität: human, mouse
756,00 €
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Anti-ATM Protein Kinase
Anti-ATM Protein Kinase

Artikelnummer: 600-401-398

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-ATM, Anti-A-T mutated, EC=2.7.11.1, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated
Anwendung: ELISA, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
684,00 €
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Anti-ATM
Anti-ATM

Artikelnummer: A300-136A

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated
Anwendung: WB, IP
Wirt: Goat
Spezies-Reaktivität: human
ab 164,00 €
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Ku-55933
Ku-55933

Artikelnummer: Cay16336-1

Ku-55933 is a potent ATP-competitive inhibitor of the ataxia-telangiectasia mutated (ATM) kinase (IC50 = 13 nM, Ki = 2.2 nM). Inhibition of ATM by Ku-55933 blocks radiation-induced phosphorylation of downstream cellular targets and sensitizes cells to the cytotoxic effects of both ionizing radiation and...
Schlagworte: ATM Kinase Inhibitor, 2-(4-morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one
Anwendung: Potent ATP-competitive ATM kinase inhibitor
CAS 587871-26-9
MW: 395.5 D
ab 38,00 €
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AZD 1390
AZD 1390

Artikelnummer: Cay36498-1

AZD 1390 is an inhibitor of Ataxia-telangiectasia mutated (ATM) kinase (IC50 = 0.78 nM). It is selective for ATM over Ataxia-telangiectasia and Rad3-related protein/kinase (ATR), PI3K, mammalian target of rapamycin (mTOR), and DNA protein kinase (DNA-PK, IC50s = >30, >12, >16, and >29.9 µM, respectively). AZD 1390...
Schlagworte: 7-fluoro-1,3-dihydro-3-methyl-1-(1-methylethyl)-8-[6-[3-(1-piperidinyl)propoxy]-3-pyridinyl]-2H-imidazo[4,5-c]quinolin-2-one
Anwendung: ATM kinase inhibitor
CAS 2089288-03-7
MW: 477.6 D
ab 68,00 €
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Anti-ATM
Anti-ATM

Artikelnummer: A300-299A

Protein function: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of...
Schlagworte: Anti-ATM, EC=2.7.11.1, Anti-A-T mutated, Anti-Serine-protein kinase ATM, Anti-Ataxia telangiectasia mutated
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
588,00 €
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