Zu "K04678" wurden 62 Artikel gefunden!
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Smurf1-IN-A01
Artikelnummer: TGM-T16904-100mg
Description: Smurf1-IN-A01 (A01) is a ubiquitin ligase Smad ubiquitination regulatory factor-1 inhibitor (Kd: 3.664 nM) that enhances BMP-2 responsiveness by preventing Smurf1-mediated Smad1/5 degradation. Target: Others. Smiles: Cc1ccnn1-c1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)c(c1)C(F)(F)F. References: Cao Y,...
| Schlagworte: | A01 |
| Anwendung: | Smurf1 inhibitor |
| CAS | 1007647-73-5 |
| MW: | 512.93 D |
ab 33,00 €
Smurf1 inhibitor 1
Artikelnummer: TGM-T70872-100mg
Description: Smurf1 inhibitor 1 is a inhibitor that promotes bone formation. Target: Others. Smiles: C(/C=C/C1=CC=CC=C1)(=O)C2=CC=C(OCC(O)=O)C=C2
| Anwendung: | Smurf1 inhibitor |
| CAS | 136068-42-3 |
| MW: | 282.29 D |
ab 1.520,00 €
SMURF2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01269-100ug
Description: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMAD7-mediated transforming growth factor beta/TGF-beta receptor ubiquitin-dependent...
| Schlagworte: | SMURF2, HECT-type E3 ubiquitin transferase SMURF2, SMAD-specific E3 ubiquitin-protein ligase 2, E3 ubiquitin-protein... |
| MW: | 90.3 kD |
ab 198,00 €
Anti-SMURF1 Monoclonal, clone 1A9H4
Artikelnummer: CSB-MA875720A0m.100
Host Species: Mouse. Isotype: IgG2a. Buffer: PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: SMURF1. Antigen Species: Human
| Schlagworte: | Anti-SMURF1, Anti-hSMURF1, Anti-KIAA1625, Anti-E3 ubiquitin-protein ligase SMURF1, Anti-SMAD ubiquitination regulatory... |
| Anwendung: | ELISA, WB, IHC, IF, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-SMURF1
Artikelnummer: CSB-PA026284.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SMURF1. Antigen Species: Human
| Schlagworte: | Anti-SMURF1, Anti-hSMURF1, Anti-KIAA1625, Anti-E3 ubiquitin-protein ligase SMURF1, Anti-SMAD ubiquitination regulatory... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-SMURF2
Artikelnummer: CSB-PA967268.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SMURF2. Antigen Species: Human
| Schlagworte: | Anti-SMURF2, Anti-hSMURF2, Anti-E3 ubiquitin-protein ligase SMURF2, Anti-SMAD ubiquitination regulatory factor 2,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...
Artikelnummer: CSB-YP872532HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG QIVVSLQSRD...
| Schlagworte: | SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 88.2 kD |
ab 242,00 €
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...
Artikelnummer: CSB-EP872532HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG QIVVSLQSRD...
| Schlagworte: | SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 113.2 kD |
ab 219,00 €
E3 ubiquitin-protein ligase SMURF2 (SMURF2), human,...
Artikelnummer: CSB-EP872532HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-748aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MSNPGGRRNG PVKLRLTVLC AKNLVKKDFF RLPDPFAKVV VDGSGQCHST DTVKNTLDPK WNQHYDLYIG KSDSVTISVW NHKKIHKKQG AGFLGCVRLL SNAINRLKDT GYQRLDLCKL GPNDNDTVRG...
| Schlagworte: | SMURF2, hSMURF2, E3 ubiquitin-protein ligase SMURF2, SMAD ubiquitination regulatory factor 2, HECT-type E3 ubiquitin... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 90.3 kD |
ab 219,00 €
E3 ubiquitin-protein ligase SMURF1 (SMURF1), partial,...
Artikelnummer: CSB-EP875720HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 198-374aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-GST-tagged. Target Protein Sequence: VESPSQDQRL QAQRLRNPDV RGSLQTPQNR PHGHQSPELP EGYEQRTTVQ GQVYFLHTQT GVSTWHDPRI PSPSGTIPGG DAAFLYEFLL QGHTSEPRDL NSVNCDELGP LPPGWEVRST VSGRIYFVDH...
| Schlagworte: | SMURF1, hSMURF1, KIAA1625, E3 ubiquitin-protein ligase SMURF1, SMAD ubiquitination regulatory factor 1, HECT-type E3... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 51.5 kD |
ab 247,00 €
E3 ubiquitin-protein ligase SMURF1 (SMURF1), partial,...
Artikelnummer: CSB-EP875720HU1a0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 198-374aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: VESPSQDQRL QAQRLRNPDV RGSLQTPQNR PHGHQSPELP EGYEQRTTVQ GQVYFLHTQT GVSTWHDPRI PSPSGTIPGG DAAFLYEFLL QGHTSEPRDL NSVNCDELGP LPPGWEVRST VSGRIYFVDH NNRTTQFTDP...
| Schlagworte: | SMURF1, hSMURF1, KIAA1625, E3 ubiquitin-protein ligase SMURF1, SMAD ubiquitination regulatory factor 1, HECT-type E3... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 24.1 kD |
ab 247,00 €
Heclin
Artikelnummer: Cay26139-1
Heclin is an inhibitor of HECT E3 ubiquitin ligases (IC50s = 6.8, 6.3, and 6.9 µM for Smurf2, Nedd4, and WWP1 HECT ligase domains, respectively). It inhibits autoubiquitination of Smurf2 in HEK293 cells expressing the human enzyme (IC50 = 9 µM) and reduces ubiquitination of Dishevelled 2 in HEK293 cells expressing...
| Schlagworte: | N-(4-acetylphenyl)-3-(5-ethyl-2-furanyl)-2-propenamide |
| Anwendung: | HECT-type E3 ubiquitin ligase inhibitor |
| CAS | 890605-54-6 |
| MW: | 283.3 D |
ab 44,00 €