Zu "K04675" wurden 78 Artikel gefunden!
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ALK2 (ACVR1) (PF197_198L), GST-Tag Recombinant
Artikelnummer: BPS-101935
Recombinant human ALK2 (PF197_198L) (activin receptor-like kinase-2), encompassing amino acids 147-end with a PF197_198L mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (Q207D), GST-Tag Recombinant
Artikelnummer: BPS-101936
Recombinant human ALK2 (Q207D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (Q207E), GST-Tag Recombinant
Artikelnummer: BPS-101937
Recombinant human ALK2 (Q207E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a Q207E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
Human ACVR1 (Activin A Receptor Type I) ELISA Kit
Artikelnummer: ELK-ELK4461.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ACVR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ACVR1. Next,...
| Schlagworte: | SKR1, TSR-I, ACVR1, ALK-2, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
ALK2 (ACVR1) (G328E), GST-Tag Recombinant
Artikelnummer: BPS-101931
Recombinant human ALK2 (G328E) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328E mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (G328V), GST-Tag Recombinant
Artikelnummer: BPS-101932
Recombinant human ALK2 (G328V) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328V mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (G328W), GST-Tag Recombinant
Artikelnummer: BPS-101933
Recombinant human ALK2 (G328W) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G328W mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
ALK2 (ACVR1) (G356D), GST-Tag Recombinant
Artikelnummer: BPS-101934
Recombinant human ALK2 (G356D) (activin receptor-like kinase-2), encompassing amino acids 147-end with a G356D mutation. This construct contains an N-terminal GST-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SKR1, ALK-2, ACVR1, TSR-I, ACTR-I, ACVRLK2, Activin receptor type-1, Activin receptor type I, Activin receptor-like kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 67 kD |
914,00 €
DMH1
Artikelnummer: Cay16679-10
Bone morphogenetic proteins (BMP) are secreted signaling proteins, many of which are involved in various developmental processes, in addition to bone formation. DMH1 is an analog of the non-selective BMP receptor inhibitor dorsomorphin (Cay-11967) that potently inhibits the kinase activity of activin receptor-like...
| Schlagworte: | BMP Inhibitor II, DorsoMorphin Homolog 1, VU036482, 4-[6-[4-(1-methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Anwendung: | ALK2 inhibitor |
| CAS | 1206711-16-1 |
| MW: | 380.4 D |
ab 52,00 €
LDN-193189 (hydrochloride)
Artikelnummer: Cay19396-1
LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are known as activin receptor-like kinases (ALKs), with an IC50 value of 4.9 nM. In in vitro kinase assays, it shows specificity for ALK1, 2, 3, and 6 (IC50s = 0.8, 0.8, 5.3, and 16.7 nM, respectively) over...
| Schlagworte: | DM-3189, 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline, dihydrochloride |
| Anwendung: | ALK1 / ALK2 / ALK3 / ALK6 inhibitor |
| CAS | 1435934-00-1 |
| MW: | 479.4 D |
ab 32,00 €
LDN-193189
Artikelnummer: Cay11802-10
Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-beta superfamily. LDN-193189 inhibits SMAD1/5/8 phosphorylation by the bone morphogenetic protein (BMP) type I receptors, which are...
| Schlagworte: | 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Anwendung: | BMP type I receptor inhibitor |
| CAS | 1062368-24-4 |
| MW: | 406.5 D |
ab 44,00 €
K02288
Artikelnummer: Cay16678-10
Activation of bone morphogenetic protein (BMP) type I receptors, also known as activin receptor-like kinases (ALK1-7), leads to the assembly of SMAD complexes, which translocate to the nucleus to induce transcriptional activation important for normal development and tissue repair. K02288 is a 2-aminopyridine-based...
| Schlagworte: | 3-[6-amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]-phenol |
| Anwendung: | ALK1 / ALK2 inhibitor |
| CAS | 1431985-92-0 |
| MW: | 352.4 D |
ab 50,00 €