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Zu "K04632" wurden 42 Artikel gefunden!
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Artikelnummer: Cay34531-1
BIM-46187 is an inhibitor of heterotrimeric G-protein signaling. It inhibits signaling through Galphai, Galphas, and Galphaq in MZ7 cells but selectively inhibits Galphaq in HEK293 and CHO cells, indicating cell-dependent inhibition. BIM-46187 (0.1-1 mg/kg) increases the paw withdrawal threshold to a mechanical...
| Schlagworte: | (2R,2'R)-3,3'-dithiobis[2-amino-1-[(8S)-8-(cyclohexylmethyl)-5,6-dihydro-2-phenylimidazo[1,2-a]pyrazin-7(8H)-yl]-1-propano... |
| Anwendung: | Heterotrimeric G-protein signaling inhibitor |
| CAS | 2489449-03-6 |
| MW: | 940.9586 D |
ab 76,00 €
Artikelnummer: NB-26906
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. G alpha srepresents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases.
| Schlagworte: | Anti-GNAS, Anti-GNAS1, Anti-Adenylate cyclase-stimulating G alpha protein, Anti-Guanine nucleotide-binding protein G(s)... |
| Anwendung: | IP, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
746,00 €
Artikelnummer: ARG65237.100
Protein function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact...
| Schlagworte: | Anti-GNAS, Anti-XLalphas, Anti-Extra large alphas protein, Anti-Adenylate cyclase-stimulating G alpha protein,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Artikelnummer: G-HUFI02529.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: NSJ-R35181-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Guanine nucleotide binding protein alpha stimulating activity polypeptide 1
| Schlagworte: | , GNAS Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Artikelnummer: NB-21007
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. Galphasrepresents one sub-family of G proteins that could mediate the stimulation of adenylyl cyclases.
| Schlagworte: | Anti-GNAS, Anti-GNAS1, Anti-Adenylate cyclase-stimulating G alpha protein, Anti-Guanine nucleotide-binding protein G(s)... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | vertebrates |
355,00 €
Artikelnummer: E-AB-14088.120
This locus has a highly complex imprinted expression pattern. It gives rise to maternally, paternally, and biallelically expressed transcripts that are derived from four alternative promoters and 5' exons. Some transcripts contain a differentially methylated region (DMR) at their 5' exons, and this DMR is commonly...
| Schlagworte: | Anti-GNAS, Anti-GNAS1, Anti-Adenylate cyclase-stimulating G alpha protein, Anti-Guanine nucleotide-binding protein G(s)... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: ATA-HPA018122.100
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 65% and to rat: 67%
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 264,00 €
Artikelnummer: CSB-EP352389HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-394aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MGCLGNSKTE DQRNEEKAQR EANKKIEKQL QKDKQVYRAT HRLLLLGAGE SGKSTIVKQM RILHVNGFNG EGGEEDPQAA RSNSDGEKAT KVQDIKNNLK EAIETIVAAM SNLVPPVELA NPENQFRVDY...
| Schlagworte: | GNAS, GNAS1, Adenylate cyclase-stimulating G alpha protein, Guanine nucleotide-binding protein G(s) subunit alpha isoforms... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 61.7 kD |
ab 292,00 €
Artikelnummer: CSB-PA147947.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GNAS. Antigen Species: Human
| Schlagworte: | Anti-GNAS, Anti-GNAS1, Anti-Adenylate cyclase-stimulating G alpha protein, Anti-Guanine nucleotide-binding protein G(s)... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: CSB-PA247539.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GNAS. Antigen Species: Human
| Schlagworte: | Anti-GNAS, Anti-GNAS1, Anti-Adenylate cyclase-stimulating G alpha protein, Anti-Guanine nucleotide-binding protein G(s)... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: TGM-T16519L-100mg
Description: BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor. Target: Others. Smiles: O=C([C@@H](N)CSSC[C@H](N)C(N(CCN1C2=NC(C3=CC=CC=C3)=C1)[C@H]2CC4CCCCC4)=O)N5[C@H](C6=NC(C7=CC=CC=C7)=CN6CC5)CC8CCCCC8.Cl.Cl.Cl.Cl. References: Favre-Guilmard C, et al. The novel inhibitor of the...
| Schlagworte: | PH-064 4HCl |
| Anwendung: | Heterotrimeric G-protein signaling inhibitor |
| CAS | 2489449-03-6 |
| MW: | 940.95 D |
ab 138,00 €