Zu "K04610" wurden 15 Artikel gefunden!
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AZ12216052
Artikelnummer: TGM-T26701-1mg
Description: AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders. Target: GPR. Smiles: CCC(C)c1ccc(NC(=O)CSCc2ccc(Br)cc2)cc1. References: Reed BT, et al. Differential modulation of retinal ganglion cell light responses by orthosteric...
| Schlagworte: | AZ 12216052, AZ-12216052 |
| Anwendung: | mGluR8 positive allosteric modulator |
| CAS | 1290628-31-7 |
| MW: | 392.35 D |
ab 52,00 €
Anti-GRM8
Artikelnummer: CSB-PA996488.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM8. Antigen Species: Human
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, FLJ41058 antibody, GLUR8 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRM8
Artikelnummer: CSB-PA232728.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, FLJ41058 antibody, GLUR8 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Anti-GRM8
Artikelnummer: CSB-PA983109.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRM8. Antigen Species: Human
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, FLJ41058 antibody, GLUR8 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
AZ 12216052
Artikelnummer: Cay29460-1
AZ 12216052 is a positive allosteric modulator of metabotropic glutamate receptor 8 (mGluR8). It potentiates glutamate-induced [35S]GTPgammaS binding in GHEK cells expressing human mGluR8b (EC50 = 1 µM). In a cell-based model of Parkinson's disease, AZ 12216052 inhibits MPP+-induced decreases in the viability of...
| Schlagworte: | 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-acetamide |
| Anwendung: | mGluR8 positive allosteric modulator |
| CAS | 1290628-31-7 |
| MW: | 392.4 D |
ab 53,00 €
ML-396
Artikelnummer: Cay29167-5
ML-396 is a positive allosteric modulator of group III metabotropic glutamate receptors (mGluRs) with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively, in calcium mobilization assays. ML-396 potentiates LSP4-2022-induced reductions in paired-pulse field excitatory post synaptic...
| Schlagworte: | VU0422288, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Anwendung: | Group III metabotropic glutamate receptor positive allosteric modulator |
| CAS | 1630936-95-6 |
| MW: | 360.2 D |
ab 44,00 €
Nanodisc Human GRM8 Protein
Artikelnummer: G-HDFP318.10
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
| Schlagworte: | GRM8, GPRC1H, mGluR8, Metabotropic glutamate receptor 8 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.486,00 €
Nanodisc Human GRM8-Strep Protein
Artikelnummer: G-HDFP1051.10
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
| Schlagworte: | GRM8, GPRC1H, mGluR8, Metabotropic glutamate receptor 8 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.336,00 €
GRM8 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100327.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | GRM8, GPRC1H, mGluR8, Metabotropic glutamate receptor 8, GLUR8, GPRC1H, MGLUR8, mGlu8, Human GRM8 full length... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 101.7 kD |
ab 1.291,00 €
Anti-GRM8
Artikelnummer: CSB-PA009035.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, FLJ41058 antibody, GLUR8 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Metabotropic Glutamate Receptor 8, CT (mGluR8,...
Artikelnummer: M3884-83E.200
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic...
| Schlagworte: | Anti-Metabotropic glutamate receptor 8 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
767,00 €
mGluR8 BioAssay(TM) ELISA Kit
Artikelnummer: 472580.96
Sample Type:, Cell line of choice, Intended Use: The mGluR8 Colorimetric Cell-Based ELISA Kit allows for qualitative detection of mGluR8 in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450 nm, Format: Cell-Based ELISA,...
| Schlagworte: | GRM8, GPRC1H, mGluR8, Metabotropic glutamate receptor 8 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
898,00 €