Zu "K04610" wurden 9 Artikel gefunden!
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AZ 12216052
Artikelnummer: Cay29460-1
AZ 12216052 is a positive allosteric modulator of metabotropic glutamate receptor 8 (mGluR8). It potentiates glutamate-induced [35S]GTPgammaS binding in GHEK cells expressing human mGluR8b (EC50 = 1 µM). In a cell-based model of Parkinson's disease, AZ 12216052 inhibits MPP+-induced decreases in the viability of...
| Schlagworte: | 2-[[(4-bromophenyl)methyl]thio]-N-[4-(1-methylpropyl)phenyl]-acetamide |
| Anwendung: | mGluR8 positive allosteric modulator |
| CAS | 1290628-31-7 |
| MW: | 392.4 D |
ab 52,00 €
ML-396
Artikelnummer: Cay29167-5
ML-396 is a positive allosteric modulator of group III metabotropic glutamate receptors (mGluRs) with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively, in calcium mobilization assays. ML-396 potentiates LSP4-2022-induced reductions in paired-pulse field excitatory post synaptic...
| Schlagworte: | VU0422288, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Anwendung: | Group III metabotropic glutamate receptor positive allosteric modulator |
| CAS | 1630936-95-6 |
| MW: | 360.2 D |
ab 43,00 €
Anti-GRM8
Artikelnummer: E-AB-67515.120
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic...
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, GRM8 Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-GRM8
Artikelnummer: G-CAB2964.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €
Anti-mGluR-8
Artikelnummer: ELK-ES5680.100
glutamate metabotropic receptor 8(GRM8) Homo sapiens L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in...
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8, mGluR-8 rabbit pAb |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Anti-Metabotropic Glutamate Receptor 8, CT (mGluR8,...
Artikelnummer: M3884-83E.200
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic...
| Schlagworte: | Anti-Metabotropic glutamate receptor 8 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
728,00 €
mGluR8 BioAssay(TM) ELISA Kit
Artikelnummer: 472580.96
Sample Type:, Cell line of choice, Intended Use: The mGluR8 Colorimetric Cell-Based ELISA Kit allows for qualitative detection of mGluR8 in plated and fixed cells. Sensitivity: >5000cells/well, Assay Time: 4.5 hours, Reactivity: Human, Mouse, Rat, Detection Method: Colorimetric 450 nm, Format: Cell-Based ELISA,...
| Schlagworte: | GRM8, GPRC1H, mGluR8, Metabotropic glutamate receptor 8 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
878,00 €
Anti-GRM8
Artikelnummer: G-CAB2964.20
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
| Schlagworte: | Anti-GRM8, Anti-mGluR8, Anti-GPRC1H, Anti-Metabotropic glutamate receptor 8 |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
149,00 €
Anti-mGluR8
Artikelnummer: ABD-8C0212.50
Custom conjugation services for this antibody as available (eg. labeling of Anti-mGluR8 with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE, PE/Cy5,...
| Schlagworte: | Anti-GRM8, Anti-GPRC1H, Anti-mGluR8, Anti-Metabotropic glutamate receptor 8, mGluR8 Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
601,00 €