Zu "K04609" wurden 21 Artikel gefunden!
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VU6005649
Artikelnummer: Cay43138-10
VU6005649 is a positive allosteric modulator (PAM) of metabotropic glutamate receptor 7 (mGluR7) and mGluR8. It enhances calcium mobilization induced by L-AP4 (Cay-14538) in HEK cells expressing mGluR7 or mGluR8 (EC50s = 0. and 2. µM, respectively). It is selective for mGluR7 and mGluR8 over mGluR1-6, as well as a...
| Schlagworte: | 3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidine |
| Anwendung: | Positive allosteric mGluR7 / mGluR8 modulator |
| CAS | 2137047-43-7 |
| MW: | 357.28 D |
ab 95,00 €
GRM7 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100119.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | GRM7, GPRC1G, mGluR7, Metabotropic glutamate receptor 7, GLUR7, GPRC1G, MGLU7, MGLUR7, NEDSHBA, PPP1R87, Human GRM7... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 102.3 kD |
ab 1.291,00 €
Anti-GRM7
Artikelnummer: CSB-PA003237.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7, FLJ40498 antibody, GLUR7 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-GRM7
Artikelnummer: CSB-PA962170.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7, FLJ40498 antibody, GLUR7 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Anti-GRM7, Internal
Artikelnummer: ARG64884.100
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
| Schlagworte: | Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
822,00 €
Anti-phospho-mGluR7 (Ser862)
Artikelnummer: 600-401-D78
Anti mGluR7 pS862 antibodiy is directed against mGluR7 phosphorylated at Ser862. GluR7 antibdody is affinity purified from monospecific antiserum by immunoaffinity purification. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide used as antigen but not by the corresponding...
| Schlagworte: | Anti-phospho-Grm7, Anti-phospho-Gprc1g, Anti-phospho-mGluR7, Anti-phospho-Metabotropic glutamate receptor 7 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat, mouse |
863,00 €
Anti-GRM7
Artikelnummer: NSJ-R34771-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Glutamate receptor, metabotropic 7 Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding...
| Schlagworte: | Anti-GRM7, Anti-mGluR7, Anti-GPRC1G, Anti-Metabotropic glutamate receptor 7, GRM7 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
790,00 €
AMN082
Artikelnummer: Cay28779-10
AMN082 is an orally bioavailable allosteric agonist of metabotropic glutamate receptor 7 (mGluR7). It inhibits cAMP accumulation induced by forskolin in CHO cells expressing human mGluR7b (EC50 = 64 nM). AMN082 (10 µM) is selective for mGluR7a and mGluR7b over mGluR1b, mGluR4, and mGluR8a with 140, 90, 15, 18, and...
| Schlagworte: | N,N'-bis(diphenylmethyl)-1,2-ethanediamine, dihydrochloride |
| Anwendung: | Allosteric mGluR7 antagonist |
| CAS | 97075-46-2 |
| MW: | 465.5 D |
ab 99,00 €
ML-396
Artikelnummer: Cay29167-25
ML-396 is a positive allosteric modulator of group III metabotropic glutamate receptors (mGluRs) with EC50 values of 108, 146, and 128 nM for mGluR4, mGluR7, and mGluR8, respectively, in calcium mobilization assays. ML-396 potentiates LSP4-2022-induced reductions in paired-pulse field excitatory post synaptic...
| Schlagworte: | VU0422288, N-[3-chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide |
| Anwendung: | Group III metabotropic glutamate receptor positive allosteric modulator |
| CAS | 1630936-95-6 |
| MW: | 360.2 D |
ab 44,00 €
Nanodisc Human GRM7-Strep Protein
Artikelnummer: G-HDFP855.10
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. [The...
| Schlagworte: | GRM7, GPRC1G, mGluR7, Metabotropic glutamate receptor 7 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.336,00 €
Anti-GRM7
Artikelnummer: CSB-PA618911ESR1HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen Affinity Purified. Target Name: GRM7. Antigen Species: Human
| Schlagworte: | Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7, FLJ40498 antibody, GLUR7 antibody, Glutamate... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-GRM7
Artikelnummer: CSB-PA009034.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GRM7, Anti-GPRC1G, Anti-mGluR7, Anti-Metabotropic glutamate receptor 7, FLJ40498 antibody, GLUR7 antibody, Glutamate... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €