Zu "K04608" wurden 36 Artikel gefunden!
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Anti-GRM6
Artikelnummer: CSB-PA180398.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-GRM6, Anti-GPRC1F, Anti-mGluR6, Anti-Metabotropic glutamate receptor 6, CSNB1B antibody, DKFZp686H1993 antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
(S)-MCPG
Artikelnummer: Cay21450-25
(S)-MCPG is an antagonist of metabotropic glutamate receptors (mGluRs) and the active component of (±)-MCPG, which is selective for Group I and Group II mGluRs. (S)-MCPG inhibits motoneuron depolarization induced by 1-amino-1,3-dicarboxycyclopentane (ACPD) in neonatal rat spinal cord in vitro and ACPD-induced...
| Schlagworte: | (+)-MCPG, (+)-alpha-methyl-4-Carboxyphenylglycine, (S)-alpha-methyl-4-Carboxyphenylglycine,... |
| Anwendung: | Non-selective group I/group II metabotropic glutamate receptor antagonist |
| CAS | 150145-89-4 |
| MW: | 209.2 D |
ab 91,00 €
MMPIP (hydrochloride)
Artikelnummer: Cay18862-1
MMPIP is a reversible allosteric antagonist of the metabotropic glutamate receptor 7 (mGluR7) that blocks agonist-induced calcium mobilization (IC50 = 26 nM). It does not affect other mGlu receptors. The modulation of mGluR7 by MMPIP is context dependent, in that it is not observed in all known mGluR7 signaling...
| Schlagworte: | 6-(4-methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[4,5-c]pyridin-4(5H)-one, monohydrochloride |
| Anwendung: | mGluR7 antagonist |
| CAS | 1215566-78-1 |
| MW: | 369.8 D |
ab 94,00 €
DCPG
Artikelnummer: Cay22072-1
DCPG is a selective agonist of the class III metabotropic glutamate receptor 8 (mGluR8), with an EC50 value of 31 nM for inhibiting forskolin-stimulated cAMP formation in AV12-664 cells expressing human mGluR8. It is selective for mGluR8 over other mGluRs (EC50s = >3.5 µM for mGluR1-7). In vitro, DCPG (1 µM)...
| Schlagworte: | (S)-3,4-DCPG, 4-[(S)-aminocarboxymethyl]-1,2-benzenedicarboxylic acid |
| Anwendung: | mGluR8a agonist |
| CAS | 201730-11-2 |
| MW: | 239.2 D |
ab 44,00 €
ACPT-I
Artikelnummer: Cay78010-10
ACPT-I is an agonist of the group III metabotropic glutamate receptors (mGluRs) mGluR4a and mGluR8 (EC50s = 7.2 and 8.2 µM, respectively) that has no effect on mGluR1a or mGluR2. It has diverse biological activity, including neuroprotective, anticonvulsant, and anxiolytic-like effects. ACPT-I (1-200 µM) reduces cell...
| Schlagworte: | (4beta)--amino-1alpha,2alpha,4-cyclopentanetricarboxylic acid |
| Anwendung: | mGluR4a / mGluR8 agonist |
| CAS | 194918-76-8 |
| MW: | 217.2 D |
ab 61,00 €
O-Phospho-L-Serine
Artikelnummer: Cay16151-10
O-Phospho-L-Serine is an agonist of the group III metabotropic glutamate receptors mGluR4a and mGluR6 (EC50s = 2-5 µM). It mimics the phosphatidylserine head group and has been shown to inhibit the proliferation of microglia and to enhance neuronal differentiation of progenitor cells.Formal Name:...
| Schlagworte: | Dexfosfoserine, L-Serine-O-Phosphate, L-SOP, O-phosphono-L-serine |
| Anwendung: | mGluR4 / mGluR6 agonist |
| CAS | 407-41-0 |
| MW: | 185.1 D |
ab 35,00 €
XAP044
Artikelnummer: Cay19095-1
XAP044 is an antagonist of the metabotropic glutamate (mGlu) receptor 7 (mGluR7), inhibiting lateral amygdala long term potentiation in brain slices from wild-type mice with an IC50 value of 88 nM. This effect is absent in mGluR7-deficient mice. XAP044 demonstrates good brain penetrance, producing wide spectrum...
| Schlagworte: | 7-hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one |
| Anwendung: | mGluR7 antagonist |
| CAS | 196928-50-4 |
| MW: | 380.1 D |
ab 44,00 €
(±)-trans-ACPD
Artikelnummer: Cay28849-5
(±)-trans-ACPD is an agonist of metabotropic glutamate receptors (mGluRs, EC50s = 15, 2, 40, 23, and 82 µM for mGluR1, -2, -3, -5, and -6, respectively, in CHO cells expressing recombinant receptors). It also activates mGluR4 in baby hamster kidney cells with an EC50 value of approximately 800 µM. (±)-trans-ACPD...
| Schlagworte: | (1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid |
| Anwendung: | mGluR agonist |
| CAS | 67684-64-4 |
| MW: | 173.2 D |
ab 52,00 €
CPPG
Artikelnummer: Cay34362-5
CPPG is an antagonist of group II and group III metabotropic glutamate receptors (mGluRs). It reverses inhibition of forskolin-induced cAMP accumulation induced by the mGluR group II selective agonist L-CCG-1 or the mGluR group III-selective agonist L-AP4 (Cay-14538) in rat cerebrocortical slices (IC50s = 46.2 and...
| Schlagworte: | alpha-Cyclopropyl-4-phosphonophenylglycine, alpha-amino-alpha-cyclopropyl-4-phosphono-benzeneacetic acid |
| Anwendung: | Group II and group III mGluR antagonist |
| CAS | 183364-82-1 |
| MW: | 271.2 D |
ab 52,00 €
Anti-GRM6
Artikelnummer: ATA-HPA014511.100
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling...
| Schlagworte: | Anti-GRM6, Anti-mGluR6, Anti-GPRC1F, Anti-Metabotropic glutamate receptor 6 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
NEU
Nanodisc Human GRM6 Protein
Artikelnummer: G-HDFP317.10
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling...
| Schlagworte: | GRM6, mGluR6, GPRC1F, Metabotropic glutamate receptor 6 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.486,00 €
NEU
Nanodisc Human GRM6-Strep Protein
Artikelnummer: G-HDFP1050.10
Protein function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Signaling...
| Schlagworte: | GRM6, mGluR6, GPRC1F, Metabotropic glutamate receptor 6 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.336,00 €