Zu "K04581" wurden 186 Artikel gefunden!
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GLP1R Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01385-10ug
Description: G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human,...
| Schlagworte: | GLP-1 receptor , GLP1R , GLP-1-R , GLP-1R , Glucagon-like peptide 1 receptor |
| MW: | 18.3 kD |
ab 48,00 €
GLP1R Protein, Rat, Recombinant (His)
Artikelnummer: TGM-TMPH-03302-10ug
Description: GLP1R Protein, Rat, Recombinant (His) is expressed in Yeast.
| Schlagworte: | GLP-1R , Glpr , GLP-1 receptor , GLP-1-R , Glucagon-like peptide 1 receptor , Glp1r |
| MW: | 15.1 kD |
ab 134,00 €
GLP1R Protein-VLP, Human, Recombinant (Flag & Strep)
Artikelnummer: TGM-TMPY-07121-100ug
Description: GLP1R Protein-VLP, Human, Recombinant (Flag & Strep) is expressed in HEK293 Cells. The accession number is P43220.
| Schlagworte: | GLP-1 , GLP-1-R , GLP-1R |
| MW: | 56.04 kD |
ab 326,00 €
GLP1R Protein-Nanodisc, Human, Recombinant (Flag & His)
Artikelnummer: TGM-TMPY-07122-100ug
Description: GLP1R Protein-Nanodisc, Human, Recombinant (Flag & His) is expressed in HEK293 Cells. The accession number is P43220.
| Schlagworte: | GLP-1-R , GLP-1 , GLP-1R |
| MW: | 58 kD |
ab 923,00 €
Semaglutide (trifluoroacetate salt)
Artikelnummer: Cay44294-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6. pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 95%. Formulation (Request formulation change): A solid. Solubility: DMSO:...
| Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
| Anwendung: | GLP-1R agonist |
| MW: | 4113.64 D |
ab 110,00 €
Rat GLP-1R/CRE Luciferase Reporter HEK293 Cell Line
Artikelnummer: BPS-83880
Rat GLP-1R/CRE Luciferase Reporter HEK293 Cell Line is an engineered HEK293 cell line expressing firefly luciferase under the control of cAMP response element (CRE), and rat GLP-1R (Rattus norvegicus Glucagon-like peptide 1 receptor, NM_012728.2). Activation of rat GLP-1R in these cells can be monitored by measuring...
| Schlagworte: | Glp1r, Glucagon-like peptide 1 receptor |
| Anwendung: | Agonist screening |
| Spezies-Reaktivität: | rat |
14.180,00 €
Bofanglutide (trifluoroacetate salt)
Artikelnummer: Cay44596-1
A GLP-1 derivative, binds to GLP-1R in HEK293 cells expressing the human receptor (IC50 = 3.67 nM), enhances glucose-stimulated insulin secretion in isolated mouse pancreatic beta-cells at 30 and 90 nM, decreases non-fasting blood glucose levels in db/db mice (ED50 = 3.024 nmol/kg), reduces food and water intake and...
| Schlagworte: | GZR18, 7-37-glucagon-like peptide 1... |
| Anwendung: | GLP-1 derivative |
| MW: | 4141.7 D |
ab 174,00 €
Exendin-4 (29-32) (trifluoroacetate salt)
Artikelnummer: Cay45083-10
A peptide fragment of exendin-4. SMILES: NCC(NCC(N1[C@H](C(N[C@H](C(O)=O)CO)=O)CCC1)=O)=O.O=C(O)C(F)(F)F. InChi Code: InChI=1S/C12H20N4O6.C2HF3O2/c13-4-9(18)14-5-10(19)16-3-1-2-8(16)11(20)15-7(6-17)12(21)22,3-2(4,5)1(6)7/h7-8,17H,1-6,13H2,(H,14,18)(H,15,20)(H,21,22),(H,6,7)/t7-,8-,/m0./s1. InChi Key:...
| Schlagworte: | Gly-Gly-Pro-Ser-OH, glycylglycyl-L-prolyl-L-serine, trifluoroacetate salt |
| Anwendung: | Exendin-4 peptide fragment |
| MW: | 316.31 D |
ab 35,00 €
Exendin-4 (29-39) (trifluoroacetate salt)
Artikelnummer: Cay45084-1
A peptide fragment of exendin-4. SMILES: [H]NCC(NCC(N1CCC[C@H]1C(N[C@@H](CO)C(N[C@@H](CO)C(NCC(N[C@H](C(N2CCC[C@H]2C(N3CCC[C@H]3C(N4CCC[C@H]4C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F. InChi Code:...
| Schlagworte: | glycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serine, trifluoroacetate salt |
| Anwendung: | Exendin-4 peptide fragment |
| MW: | 909.95 D |
ab 55,00 €
Naperiglipron
Artikelnummer: Cay45151-1
A GLP-1R agonist, induces cAMP production in HEK293 cells expressing human GLP-1R (EC50 = 1.14 nM), reduces blood glucose levels in human GLP1R knock-in mice (ED50 = 0.07 mg/kg). SMILES: O=C(C1=CC=C(N=C2CC3=C(F)C=C(C4=CC=CC(OCC5=C(F)C=C(C#N)C=C5)=N4)C(C)=C3)C(N2C[C@H]6OCC6)=C1)O. InChi Code:...
| Schlagworte: | LY3549492,... |
| Anwendung: | GLP-1R agonist |
| CAS | 2572566-11-9 |
| MW: | 580.59 D |
ab 69,00 €
GLP-2R/CRE Luciferase Reporter HEK293 Cell Line
Artikelnummer: BPS-83623
The GLP-2R/CRE Luciferase Reporter HEK293 Cell Line is a HEK293 cell line engineered to express Glucagon-like peptide 2 receptor (GLP-2R) (NM_004246.3). The construct was delivered by lentiviral transduction of CRE/CREB Luciferase Reporter HEK293 Cell Line (#60515), which express a firefly luciferase reporter driven...
| Schlagworte: | GLP1R, Glucagon-like peptide 1 receptor |
| Anwendung: | GLP-2R agonist screening |
| Wirt: | Human cells |
| Spezies-Reaktivität: | human |
14.180,00 €
Semaglutide
Artikelnummer: AG-CP3-0040-M025
Synthetic. Soluble in aqueous solution (5% AcOH) (1mg/ml). Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to...
| Schlagworte: | Semaglutide (free acid), NN 9535, NNC 0113-0217, Ozempic,... |
| Anwendung: | Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist |
| CAS | 910463-68-2 |
| MW: | 4113.6 D |
ab 33,00 €