- Suchergebnis für K04581
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Zu "K04581" wurden 52 Artikel gefunden!
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NEU
Artikelnummer: Cay39740-1
V-0219 is a positive allosteric modulator (PAM) of the glucagon-like peptide 1 receptor (GLP-1R). It is selective for GLP-1R over a panel of 54 other receptors, ion channels, and transporters at 10 µM. V-0219 (0.001-1 nM) potentiates GLP-1-induced cAMP accumulation in HEK293 cells expressing human GLP-1R. It also...
Schlagworte: | 4-[[1-[[3-[4-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]methyl]-3-piperidinyl]methyl]-morpholine, monohydrochloride |
Anwendung: | GLP-1R positive allosteric modulator |
CAS | 2922283-73-4 |
MW: | 446.9 D |
ab 34,00 €
Artikelnummer: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Schlagworte: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Anwendung: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
ab 117,00 €
Artikelnummer: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Anwendung: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
ab 34,00 €
Artikelnummer: Cay36912-1
Exendin-4 (3-39) amide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and an active metabolite of exendin-4 (48-86) amide (Cay-11096). It is formed from exendin-4 (48-86) amide in rat liver homogenates. Exendin-4 (3-39) amide induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 9...
Schlagworte: | Exendin (3-39),... |
Anwendung: | GLP-1R agonist, active exendin-4 (48-86) amide metabolite |
MW: | 3992.4 D |
ab 47,00 €
Artikelnummer: Cay39739-10
Lixisenatide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and a derivative of exendin-4 (48-86) amide (Cay-11096). It binds to CHO-K1 cells expressing human GLP-1R (IC50 = 1.4 nM). Lixisenatide (100 pM) inhibits Il-1beta- and IFN-gamma-induced apoptosis in INS-1 rat pancreatic beta-cells. It lowers...
Schlagworte: | AVE-0010, ZP10A |
Anwendung: | GLP-1R agonist, hypoglycemic agent |
CAS | 1997361-87-1 |
MW: | 4858.5 D |
ab 101,00 €
Artikelnummer: Cay39741-1
Orforglipron is a nonpeptide agonist of the glucagon-like peptide 1 receptor (GLP-1R). It induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = 3.05 nM) and is selective for GLP-1R over the glucagon receptor (GCGR), gastric inhibitory polypeptide (GIP) receptor, and GLP-2R at 100 nM. Orforglipron...
Schlagworte: | LY3502970, OWL833,... |
Anwendung: | Nonpeptide GLP-1R agonist, hypoglycemic agent |
CAS | 2212020-52-3 |
MW: | 883 D |
ab 80,00 €
Artikelnummer: Cay40466-1
Glucagon-like peptide 1 receptor (GLP-1R) is a transmembrane G protein-coupled receptor (GPCR) and a member of the secretin family of receptors. It is composed of extracellular and transmembrane domains responsible for ligand binding and an intracellular domain responsible for signaling. It is primarily expressed in...
Schlagworte: | GLP1R, GLP-1R, GLP-1R, GLP-1-R, GLP-1-R, GLP-1 receptor, GLP-1 receptor, Glucagon-like peptide 1 receptor, Glucagon-like... |
Exprimiert in: | Human cells |
Ursprungsart: | human |
ab 401,00 €
Artikelnummer: ELK-ELK6119.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse GLP1R. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse GLP1R. Next,...
Schlagworte: | Glp1r, GLP-1R, GLP-1-R, GLP-1 receptor, Glucagon-like peptide 1 receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: ELK-ELK7585.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat GLP1R. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat GLP1R. Next,...
Schlagworte: | Glpr, Glp1r, GLP-1R, GLP-1-R, GLP-1 receptor, Glucagon-like peptide 1 receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK4792.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GLP1R. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GLP1R. Next,...
Schlagworte: | GLP1R, GLP-1R, GLP-1-R, GLP-1 receptor, Glucagon-like peptide 1 receptor |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-EA293.50
The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Protein function: G-protein coupled receptor for glucagon-like peptide 1 (GLP- 1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers...
Schlagworte: | Anti-GLP1R, Anti-GLP-1R, Anti-GLP-1-R, Anti-GLP-1 receptor, Anti-Glucagon-like peptide 1 receptor, GLP1R Rabbit pAb |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
169,00 €
Artikelnummer: AG-CP3-0040-M025
Synthetic. Soluble in aqueous solution (5% AcOH) (1mg/ml). Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner. Longer-acting alternative to liraglutide. Chemically similar to...
Schlagworte: | Semaglutide (free acid), NN 9535, NNC 0113-0217, Ozempic,... |
Anwendung: | Antidiabetic, Glucagon-like peptide 1 (GLP-1) receptor agonist |
MW: | 4113.6 D |
ab 66,00 €