Zu "K04580" wurden 64 Artikel gefunden!
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Rat GIPR/CRE Luciferase Reporter HEK293 Cell Line
Artikelnummer: BPS-83881
Rat GIPR/CRE Luciferase Reporter HEK293 Cell Line is an engineered HEK293 cell line expressing firefly luciferase under the control of cAMP response element (CRE), and rat GIPR (Rattus norvegicus Gastric Inhibitory Polypeptide receptor, NM_012714.2). Activation of GIPR in these cells can be monitored by measuring...
| Schlagworte: | Gipr, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Anwendung: | Agonist screening/characterization |
| Spezies-Reaktivität: | rat |
15.501,00 €
GIPR hFc Chimera, Human
Artikelnummer: GSC-Z05354-100
The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
| Schlagworte: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Ursprungsart: | human |
| MW: | 38.91 kD |
ab 457,00 €
![GIPR[Biotin], His & Avi, Human](https://www.biomol.com/media/image/70/77/61/GSC-Z04472-100_200x200.png "GIPR[Biotin], His & Avi, Human")
GIPR[Biotin], His & Avi, Human
Artikelnummer: GSC-Z04472-100
The gastric inhibitory polypeptide receptor (GIPR), a G protein-coupled receptor (GPCR) that regulates glucose metabolism and insulin secretion, is a target for the development of therapeutic agents to address type 2 diabetes and obesity.
| Schlagworte: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
| Ursprungsart: | human |
| MW: | 15.88 kD |
ab 887,00 €
CHO-K1/GIP/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00486
Recombinant CHO-K1 cells stably overexpress human gastric inhibitory polypeptide receptor (GIP) on the surface and contain high levels of G protein Galphas to couple with the receptor in downstream signaling pathways.
| Schlagworte: | GIPR, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor |
11.424,00 €
Tirzepatide (sodium salt)
Artikelnummer: Cay39748-5
Tirzepatide is an agonist of glucagon-like peptide 1 receptor (GLP-1R) and gastric inhibitory polypeptide (GIP) receptor. It induces cAMP production in HEK293 cells expressing human GLP-1R or human GIP receptor (EC50s = 6.54 and 1.01 nM, respectively). Tirzepatide (100 nM) induces receptor internalization in HEK293...
| Schlagworte: | LY3298176,... |
| Anwendung: | Dual GLP-1R / GIPR agonist |
| MW: | 4813.5 D |
ab 42,00 €
Retatrutide (sodium salt)
Artikelnummer: Cay39747-1
Retatrutide is a triple agonist of the glucagon receptor (GCGR), glucagon-like peptide 1 receptor (GLP-1R), and gastric inhibitory polypeptide receptor (GIP receptor), also known as the glucose-dependent insulinotropic polypeptide receptor. It induces cAMP accumulation in HEK293 cells expressing the human GCGR,...
| Schlagworte: | LY3437943,... |
| Anwendung: | GCGR / GLP-1R / GIPR triple agonist |
| MW: | 4731.3 D |
ab 85,00 €
Retatrutide
Artikelnummer: TGM-T76279-25mg
Description: Retatrutide (LY3437943) is a triple agonist of the glucagon receptor, glucose-dependent insulinotropic polypeptide receptor, and glucagon-like peptide-1 receptor (GLP-1R), and inhibits GCGR, GIPR, and GLP-1R.Retatrutide can be used to study obesity. Target: Glucagon Receptor. References: Tamer Coskun,...
| Schlagworte: | LY3437943 |
| Anwendung: | Targets glucagon receptor (GCGR) |
| CAS | 2381089-83-2 |
| MW: | 4731.33 D |
ab 233,00 €
GIP Receptor (human) Reporter Assay Kit
Artikelnummer: Cay502875-1
Cayman's reverse transfection reporter assays have overcome many of the disadvantages of other transfection approaches. In this method, a proprietary transfection complex containing DNA and an optimized mixture of lipids and proteins has been evenly applied and processed on the culture surface of multi-well plates....
| Schlagworte: | GIPR, Glucose-dependent Insulinotropic Polypeptide Receptor |
| Anwendung: | Reverse transfection reporter assay |
| Spezies-Reaktivität: | human |
690,00 €
GIPR/CRE Luciferase Reporter HEK293 Cell Line
Artikelnummer: BPS-78589
Recombinant HEK293 cells expressing the firefly luciferase gene under the control of cAMP response element (CRE), and with forced expression of human GIPR (Gastric Inhibitory Polypeptide receptor, NM_000164.4). Activation of GIPR in these cells can be monitored by measuring luciferase activity. The functionality of...
| Schlagworte: | GIPR, GIP-R, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor, |
| Anwendung: | Cellular context agonist screening/characterization |
| Spezies-Reaktivität: | human |
15.501,00 €
Anti-GIPR
Artikelnummer: ARG66400.100
Protein function: This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. [The UniProt Consortium]
| Schlagworte: | Anti-GIPR, Anti-GIP-R, Anti-Gastric inhibitory polypeptide receptor, Anti-Glucose-dependent insulinotropic polypeptide... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Gastric inhibitory polypeptide receptor (GIPR), partial,...
Artikelnummer: CSB-BP009438HU1.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 22-138aa. Protein Length: Partial. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: RAETGSKGQT AGELYQRWER YRRECQETLA AAEPPSGLAC NGSFDMYVCW DYAAPNATAR ASCPWYLPWH HHVAAGFVLR QCGSDGQWGL WRDHTQCENP EKNEAFLDQR...
| Schlagworte: | GIPR, GIP-R, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 17.3 kD |
ab 489,00 €
Gastric inhibitory polypeptide receptor (GIPR), human,...
Artikelnummer: CSB-CF009438HU.100
Organism: Homo sapiens (Human). Source: in vitro E.coli expression system. Expression Region: 22-466aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: RAETGSKGQT AGELYQRWER YRRECQETLA AAEPPSGLAC NGSFDMYVCW DYAAPNATAR ASCPWYLPWH HHVAAGFVLR QCGSDGQWGL...
| Schlagworte: | GIPR, GIP-R, Gastric inhibitory polypeptide receptor, Glucose-dependent insulinotropic polypeptide receptor, Recombinant... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli in vitro |
| Ursprungsart: | human |
| MW: | 52.4 kD |
ab 943,00 €