Zu "K04482" wurden 104 Artikel gefunden!
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Emzadirib
Artikelnummer: Cay44841-1
Emzadirib is an inhibitor of RAD51 with anticancer activity in vitro and in animal models. Formal Name: N-[3-[[(1,1-dimethylethyl)amino]sulfonyl]-4-[2-[trans-4-[[(1-methylethoxy)carbonyl]amino]cyclohexyl]-5-thiazolyl]phenyl]-, carbamic acid, 1-methylethyl ester. CAS Number: 2301085-04-9. Synonyms: CYT0851. Molecular...
| Schlagworte: | CYT0851,... |
| Anwendung: | RAD51 inhibitor |
| CAS | 2301085-04-9 |
| MW: | 580.76 D |
ab 102,00 €
Anti-Recombinant Rad51, clone 7A3
Artikelnummer: E-AN300932L.100
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and...
| Schlagworte: | Anti-RAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1, Recombinant Rad51 Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
RAD51 Inhibitor B02
Artikelnummer: Cay22133-5
RAD51 inhibitor B02 is an inhibitor of RAD51 recombinase (IC50 = 27.4 µM in a FRET-based DNA strand exchange assay), which is often overexpressed in cancer cells. It is selective for RAD51 over the E. coli homologue RecA at concentrations up to 250 µM and over RAD54 at concentrations up to 200 µM. RAD51 inhibitor...
| Schlagworte: | 3-(phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone |
| CAS | 1290541-46-6 |
| MW: | 339.4 D |
ab 56,00 €
RAD51-IN-17
Artikelnummer: Cay42253-10
A RAD51 inhibitor, inhibits DNA damage-induced RAD51 foci formation in MDA-MB-231 TNBC cells at 10 µM, enhances irradiation-induced reductions in the proliferation of MDA-MB-231 cells at 10 µM. Formulation: A solid. InChI:...
| Schlagworte: | AFN39186, RAD51 Inhibitor 17, 3-[(4-chlorophenyl)methyl]-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone |
| Anwendung: | RAD51 inhibitor |
| CAS | 2101739-18-6 |
| MW: | 373.8 D |
ab 41,00 €
RS-1
Artikelnummer: Cay21037-5
RS-1 is an activator of DNA repair protein RAD51 (Kd = 48-107 for human RAD51 with different cofactors present). It stimulates homologous strand assimilation activity at least 5- to 11-old, enhancing homologous recombination activity of hRAD51. RS-1 is a potent enhancer of CRISPR-mediated genome editing, increasing...
| Schlagworte: | 4-bromo-N-(4-bromophenyl)-3-[[(phenylmethyl)amino]sulfonyl]-benzamide |
| Anwendung: | RAD51 activator |
| CAS | 312756-74-4 |
| MW: | 524.2 D |
ab 49,00 €
Anti-RAD51, clone 1281CT886.273.179.159
Artikelnummer: ARG55751.100
Protein function: Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part...
| Schlagworte: | Anti-RAD51, Anti-RAD51A, Anti-hRAD51, Anti-HsRAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
600,00 €
Anti-RAD51, clone 4H10-G5-H4
Artikelnummer: ARG56558.100
Protein function: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to...
| Schlagworte: | Anti-RAD51, Anti-RAD51A, Anti-hRAD51, Anti-HsRAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1 |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey, hamster |
658,00 €
Anti-Rad51
Artikelnummer: NSJ-R31736
0.5mg/ml if reconstituted with 0.2ml sterile DI water.
| Schlagworte: | Anti-RAD51, Anti-hRAD51, Anti-RAD51A, Anti-HsRAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1, Rad51... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
RI-1
Artikelnummer: Cay24182-1
RI-1 is an irreversible inhibitor of RAD51 (IC50s = 5-30 µM), a protein that is central to homologous recombination during DNA repair and is overexpressed in a wide range of human cancer cell types. RI-1 selectively inhibits homologous recombination without inhibiting single strand annealing. It binds directly to...
| Schlagworte: | 3-chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
| Anwendung: | RAD51 inhibitor |
| CAS | 415713-60-9 |
| MW: | 361.6 D |
ab 49,00 €
RI-2
Artikelnummer: Cay18397-1
RI-2 is a reversible inhibitor of RAD51 (IC50 = 44.2 µM), a protein that is central to the homologous recombination process initiated upon DNA double-strand breaks and is often overexpressed in a wide range of human cancer cell types. At 150 µM, it has been shown to inhibit DNA repair and to sensitize cancer cells...
| Schlagworte: | 1-(3,4-dichlorophenyl)-3-(4-methoxyphenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione |
| Anwendung: | RAD51 inhibitor |
| CAS | 1417162-36-7 |
| MW: | 433.3 D |
ab 73,00 €
Anti-RAD51, clone RAD51/2765
Artikelnummer: NSJ-V7328SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2. Elevated expression of RAD51...
| Schlagworte: | Anti-RAD51, Anti-hRAD51, Anti-RAD51A, Anti-HsRAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1, RAD51... |
| Anwendung: | IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
Anti-RAD51, clone RAD51/2753
Artikelnummer: NSJ-V7327-100UG
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. RAD51 is one of the key factors of DNA repair by homologous recombination and has been shown to have anti-apoptotic activity in tumor cells. RAD51 protein interacts with a variety of tumor suppressor proteins including p53, BRCA1 and BRCA2....
| Schlagworte: | Anti-RAD51, Anti-hRAD51, Anti-RAD51A, Anti-HsRAD51, Anti-RAD51 homolog A, Anti-DNA repair protein RAD51 homolog 1, RAD51... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €