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Zu "K04465" wurden 46 Artikel gefunden!
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Artikelnummer: Cay37540-10
DIM-C-pPhCO2Me is a nerve growth factor IB (NR4A1) antagonist. It decreases expression of the mRNA encoding integrin beta1 (ITGB1) in MIA PaCa-2 and PANC-1 pancreatic and RKO and SW480 colon cancer cells when used at concentrations of 15 and 20 µM. DIM-C-pPhCO2Me (15 and 20 µM) decreases the migration and adhesion...
Schlagworte: | 4-(di-1H-indol-3-ylmethyl)-benzoic acid, methyl ester |
Anwendung: | NR4A1 antagonist |
CAS | 151358-48-4 |
MW: | 380.4 D |
ab 77,00 €
Artikelnummer: ELK-ELK6295.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat NGFIB. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat NGFIB. Next,...
Schlagworte: | Hmr, NUR77, Nr4a1, NGFI-B, Orphan nuclear receptor HMR, Nerve growth factor-induced protein I-B, Nuclear receptor... |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: Cay17501-1
Cytosporone B is a naturally occurring agonist for the nuclear receptor Nur77 (IC50 = 0.278 nM). Activation of Nur77 with cytosporone B induces the expression of Nur77-dependent genes, including the gene for Nur77 itself. Signaling through Nur77 induces apoptosis in cancer cells and retards xenograft tumor growth....
Schlagworte: | Csn-B, Dothiorelone G, 3,5-dihydroxy-2-(1-oxooctyl)-benzeneacetic acid, ethyl ester |
Anwendung: | Nur77 agonist |
CAS | 321661-62-5 |
MW: | 322.4 D |
ab 43,00 €
Artikelnummer: NSJ-R34125-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nuclear receptor subfamily 4, group A, member 1, NR4A1 Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during...
Schlagworte: | Anti-NR4A1, Anti-Nur77, Anti-GFRP1, Anti-ST-59, Anti-Testicular receptor 3, Anti-Orphan nuclear receptor HMR, Anti-Early... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay27980-5
C-DIM5 is a para-phenyl-substituted diindolylmethane (C-DIM) and an agonist of the orphan receptor nuclear receptor-related protein 77 (Nur77). It selectively activates Nur77 over peroxisome proliferator receptor gamma (PPARgamma) in reporter assays when used at a concentration of 20 µM. C-DIM5 (10, 15, and 20 µM)...
Schlagworte: | DIM-C-pPhOCH3, 3,3'-[(4-methoxyphenyl)methylene]bis-1H-indole |
Anwendung: | Nur77 (NR4A1) agonist |
CAS | 33985-68-1 |
MW: | 352.4 D |
ab 43,00 €
Artikelnummer: Cay30694-5
C-DIM8 is a para-phenyl-substituted diindolylmethane (C-DIM) and an antagonist of the orphan receptor nuclear receptor-related protein 77 (Nur77). It inhibits reporter gene expression induced by the Nur77 agonist C-DIM5 (Cay-27980) in PANC-28 cells when used at a concentration of 20 µM. C-DIM8 (10, 15, and 20 µM)...
Schlagworte: | 1,1-bis-(3'-indolyl)-1-(p-hydroxyphenyl)methane, DIM-C-pPhOH, 4-(di-1H-indol-3-ylmethyl)-phenol |
Anwendung: | Nur77 antagonist |
CAS | 151358-47-3 |
MW: | 338.4 D |
ab 48,00 €
Artikelnummer: ARG64105.100
Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...
Schlagworte: | Anti-Nur77, Anti-GFRP1, Anti-ST-59, Anti-NR4A1, Anti-Testicular receptor 3, Anti-Orphan nuclear receptor TR3, Anti-Early... |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: NSJ-R30761
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nuclear receptor subfamily 4 group A member 1, also called NAK1, GFRP1, TR3, NUR77 or NGFIB, is a protein that in humans is encoded by the NR4A1 gene, and is a member of the Nur nuclear receptor family of intracellular transcription factors. NR4A1 is involved in...
Schlagworte: | Anti-NR4A1, Anti-Nur77, Anti-GFRP1, Anti-ST-59, Anti-Testicular receptor 3, Anti-Orphan nuclear receptor HMR, Anti-Early... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-R32021
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nuclear receptor subfamily 4, group A, member 1, also called NAK1, GFRP1, TR3, NUR77 or NGFIB, is a protein that in humans is encoded by the NR4A1 gene, and a member of the Nur nuclear receptor family of intracellular transcription factors. NR4A1 is involved in...
Schlagworte: | Anti-GFRP1, Anti-NR4A1, Anti-Nur77, Anti-ST-59, Anti-Testicular receptor 3, Anti-Early response protein NAK1, Anti-Orphan... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-F49565-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the...
Schlagworte: | Anti-NR4A1, Anti-Nur77, Anti-GFRP1, Anti-ST-59, Anti-Testicular receptor 3, Anti-Orphan nuclear receptor HMR, Anti-Early... |
Anwendung: | WB, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 326,00 €
Artikelnummer: ARG40501.100
Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...
Schlagworte: | Anti-GFRP1, Anti-NR4A1, Anti-Nur77, Anti-ST-59, Anti-Testicular receptor 3, Anti-Early response protein NAK1, Anti-Orphan... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Artikelnummer: ARG66688.100
Protein function: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'- AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the...
Schlagworte: | Anti-phospho-NR4A1, Anti-phospho-Nur77, Anti-phospho-GFRP1, Anti-phospho-ST-59, Anti-phospho-Testicular receptor 3,... |
Anwendung: | IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
584,00 €