Zu "K04456" wurden 605 Artikel gefunden!
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Human AKT (Total) ELISA Kit
Artikelnummer: ELK-ELK0371.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AKT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AKT. Next,...
| Schlagworte: | PKB, AKT1, PKB alpha, RAC-PK-alpha, Protein kinase B, Proto-oncogene c-Akt, Protein kinase B alpha, RAC-alpha... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 352,00 €
Human PKBg (Protein Kinase B Gamma) ELISA Kit
Artikelnummer: ELK-ELK1550.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PKBg. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PKBg. Next,...
| Schlagworte: | PKBG, AKT3, STK-2, PKB gamma, EC=2.7.11.1, RAC-PK-gamma, Protein kinase Akt-3, Protein kinase B gamma, RAC-gamma... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-Akt3
Artikelnummer: ELK-EA052.100
RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Protein function: AKT3 is one of 3 closely related serine/threonine-protein...
| Schlagworte: | Anti-AKT3, Anti-PKBG, Anti-STK-2, Anti-PKB gamma, EC=2.7.11.1, Anti-RAC-PK-gamma, Anti-Protein kinase Akt-3, Anti-Protein... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
Anti-Akt2
Artikelnummer: ELK-EA235.50
RAC-beta serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT2 gene. This gene is a putative oncogene encoding a protein belonging to the AKT subfamily of serine/threonine kinases that contain SH2-like (Src homology 2-like) domains. The encoded protein is a general protein kinase capable...
| Schlagworte: | Anti-AKT2, Anti-PKB beta, Anti-RAC-PK-beta, EC=2.7.11.1, Anti-Protein kinase Akt-2, Anti-Protein kinase B beta,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
MK-2206 (hydrochloride)
Artikelnummer: Cay11593-1
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKBalpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK-2206 is an orally active, allosteric Akt inhibitor that is equally potent toward purified human recombinant Akt1 and Akt2...
| Schlagworte: | 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, dihydrochloride |
| Anwendung: | Allosteric Akt inhibitor |
| CAS | 1032350-13-2 |
| MW: | 480.4 D |
ab 58,00 €
COVID-19 Forschung
MK2206 (dihydrochloride)
Artikelnummer: LKT-M4000.1
MK2206 is a Akt inhibitor, is also an orally bioavailable allosteric inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor MK2206 binds to and inhibits the activity of Akt in a non-ATP competitive manner, which may result in the inhibition of...
| Schlagworte: | MK-2206 . 2HCl, 8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-8,9-dihydro-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one... |
| Anwendung: | AKT inhibitor |
| CAS | 1032350-13-2 |
| MW: | 445.94 D |
ab 79,00 €
(-)-Deguelin
Artikelnummer: Cay10010706-5
(-)-Deguelin is a rotenoid that has been found in T. vogelii and has diverse biological activities. It inhibits mitochondrial complex I, also known as NADH dehydrogenase, activity in bovine heart electron transport particles and phorbol 12-myristate 13-acetate-induced ornithine decarboxylase (ODC) activity in MCF-7...
| Schlagworte: | (-)-cis-Deguelin, 13,13aS-dihydro-9,10-dimethoxy-3,3-dimethyl-3H-[1]benzopyrano[3,4-b]pyrano[2,3-h][1]benzopyran-7(7aS)-one |
| Anwendung: | Chemopreventive effector |
| CAS | 522-17-8 |
| MW: | 394.4 D |
ab 70,00 €
Akt Inhibitor X
Artikelnummer: Cay14863-1
Akt functions as a key component in multiple signaling pathways to promote cell survival by mediating resistance to apoptosis. Akt inhibitor X is a cell permeable phenoxazine derivative that suppresses insulin-like growth factor 1 (IGF-1)-stimulated phosphorylation of Akt with an IC50 value of 1-2 µM. This compound...
| Schlagworte: | 10-DEBC, 2-chloro-N,N-diethyl-10H-phenoxazine-10-butanamine, monohydrochloride |
| Anwendung: | Akt phosphorylation inhibitor |
| CAS | 925681-41-0 |
| MW: | 381.3 D |
ab 69,00 €
AKT1 mutant (T308A S473A) Human Recombinant Protein
Artikelnummer: 009-001-P22
Recombinant protein mutant corresponds to amino acids 1 to 480 of mature human AKT1, Akt isoform 1. There are two point mutation of key activating residues, T308A and S473A. The recombinant protein contains a polyhistidine affinity tag at the amino terminus. Purity is greater than 90% as determined by reducing and...
| Schlagworte: | PKB, AKT1, PKB alpha, EC=2.7.11.1, RAC-PK-alpha, Protein kinase B, Proto-oncogene c-Akt, Protein kinase B alpha, RAC-alpha... |
| Anwendung: | WB |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
454,00 €
Akt Inhibitor VIII
Artikelnummer: Cay14870-1
Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 µM). It is a poor or ineffective inhibitor of a wide range of other serine-threonine kinases. Akt inhibitor VIII is cell permeable, blocking insulin...
| Schlagworte: | 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-2H-benzimidazol-2-one |
| Anwendung: | AKT1 / AKT2 inhibitor |
| CAS | 612847-09-3 |
| MW: | 551.7 D |
ab 39,00 €
Anti-phospho-AKT (Ser473), clone 17F6.B11
Artikelnummer: 200-301-268S
Protein function: AKT1 is one of 3 closely related serine/threonine- protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range...
| Schlagworte: | Anti-phospho-PKB, Anti-phospho-AKT1, Anti-phospho-PKB alpha, EC=2.7.11.1, Anti-phospho-RAC-PK-alpha, Anti-phospho-Protein... |
| Anwendung: | ELISA, FC, IHC, IFM, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 180,00 €
GSK690693
Artikelnummer: Cay16891-1
GSK690693 is an ATP-competitive, pan-Akt kinase inhibitor with IC50 values of 2, 13, and 9 nM for Akt1, 2, and 3, respectively. It also inhibits other members of the AGC kinase family, including AMPK, DAPK3, PAKs, PKA, PKC, PKG, and PrkX (IC50 values range from 2-81 nM). By preventing the phosphorylation of...
| Schlagworte: | 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-... |
| Anwendung: | Akt kinase inhibitor |
| CAS | 937174-76-0 |
| MW: | 425.5 D |
ab 66,00 €