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Zu "K04453" wurden 51 Artikel gefunden!
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Artikelnummer: E-AN300263P.100
The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and...
| Schlagworte: | bHLHd4, BHLHD4, Protein max, Myc-associated factor X, Class D basic helix-loop-helix protein 4, Recombinant MAX/MYC... |
| Anwendung: | WB, FCM, ICC/IF, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
462,00 €
Artikelnummer: A302-866A-T
Protein function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a...
| Schlagworte: | Anti-MAX, Anti-BHLHD4, Anti-bHLHd4, Anti-Protein max, Anti-Myc-associated factor X, Anti-Class D basic helix-loop-helix... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: Cay39622-5
MYCi975 is an inhibitor of the protein-protein interaction between Myc and Myc-associated factor X (MAX). It binds to Myc (Kd = 2.75 µM) and increases GSK3beta-mediated Myc phosphorylation in a cell-free assay. MYCi975 (5 and 10 µM) decreases the viability of MyC-CaP and LNCaP prostate cancer cells. It induces...
| Schlagworte: | NUCC-0200975,... |
| Anwendung: | Myc-MAX protein-protein interaction inhibitor |
| CAS | 2289691-01-4 |
| MW: | 561.3 D |
ab 260,00 €
Artikelnummer: ARG55340.100
Protein function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a...
| Schlagworte: | Anti-MAX, Anti-BHLHD4, Anti-bHLHd4, Anti-Protein max, Anti-Myc-associated factor X, Anti-Class D basic helix-loop-helix... |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Artikelnummer: ARG63125.100
Protein function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a...
| Schlagworte: | Anti-MAX, Anti-bHLHd4, Anti-BHLHD4, Anti-Protein max, Anti-Myc-associated factor X, Anti-Class D basic helix-loop-helix... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
871,00 €
Artikelnummer: G-HUFI00662.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: NSJ-R33757-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: MYC associated factor X Protein function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The...
| Schlagworte: | Anti-MAX, Anti-bHLHd4, Anti-BHLHD4, Anti-Protein max, Anti-Myc-associated factor X, Anti-Class D basic helix-loop-helix... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
836,00 €
Artikelnummer: Cay15929-25
The Myc proto-oncogenes interact with Max to form a dimer that regulates gene transcription. The protein c-Myc, in particular, promotes gene expression relevant to cell growth and thus drives cancer. 10058-F4 is a cell-permeable thiazolidinone that inhibits the dimerization of c-Myc and Max at 64 µM, preventing...
| Schlagworte: | 5-[(4-ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Anwendung: | c-Myc / Max dimerization inhibitor |
| CAS | 403811-55-2 |
| MW: | 249.4 D |
ab 93,00 €
Artikelnummer: ATA-HPA003474.100
Protein function: Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a...
| Schlagworte: | Anti-BHLHD4, Anti-bHLHd4, Anti-Protein max, Anti-Myc-associated factor X, Anti-Class D basic helix-loop-helix protein 4 |
| Anwendung: | IHC, ChIP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: Cay37486-1
10074-A4 is an inhibitor of the protein-protein interaction between c-Myc and the c-Myc associated protein Max. It inhibits c-Myc and Max heterodimerization when used at a concentration of 5 µM and reduces the proliferation of Rat1 and TGR-1 rat fibroblasts but not TGR-1 Myc knockout fibroblasts at 32 µM. 10074-A4...
| Schlagworte: | 3-[3-(3,6-dichloro-9H-carbazol-9-yl)-2-hydroxypropyl]-2,4-thiazolidinedione |
| Anwendung: | c-Myc / Max protein-protein interaction inhibitor |
| CAS | 312631-87-1 |
| MW: | 409.3 D |
ab 54,00 €
Artikelnummer: Cay37767-1
Mycro 3 is an inhibitor of the protein-protein interaction between c-Myc and c-Myc associated protein (Max, IC50 = 40 µM). It is also an inhibitor of Max dimerization (IC50 = 88 µM). Mycro 3 selectively reduces the viability of c-Myc-expressing TGR-1 fibroblasts over c-Myc-null HO15.19 fibroblasts (IC50s = 0.25 and...
| Schlagworte: | 5-[[[7-(chlorodifluoromethyl)-5-(2-furanyl)pyrazolo[1,5-a]pyrimidin-2-yl]carbonyl]amino]-1-phenyl-1H-pyrazole-4-carboxylic... |
| Anwendung: | C-Myc-Max protein-protein interaction inhibitor |
| CAS | 944547-46-0 |
| MW: | 526.9 D |
ab 122,00 €
Artikelnummer: ELK-ELK3733.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAX. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAX. Next,...
| Schlagworte: | BHLHD4, bHLHd4, Protein max, Myc-associated factor X, Class D basic helix-loop-helix protein 4 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €