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Zu "K04451" wurden 574 Artikel gefunden!
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-10 %
Rabattaktion
Artikelnummer: ELK-ELK1507.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TP53. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TP53. Next,...
Schlagworte: | P53, TP53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, Cellular tumor antigen p53 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK1508.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TP53. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TP53. Next,...
Schlagworte: | P53, Tp53, Tumor suppressor p53, Cellular tumor antigen p53 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK1509.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat TP53. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TP53. Next,...
Schlagworte: | P53, Tp53, Tumor suppressor p53, Cellular tumor antigen p53 |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-EA173.50
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. Protein function: Acts as a tumor...
Schlagworte: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
169,00 €
152,10 €
Artikelnummer: Cay13326-5
Pifithrin-alpha is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. It prevents p53-mediated apoptosis induced by cytotoxic compounds in C8 cells at 10 µM and in human umbilical vein endothelial cells at 30 µM. Pifithrin-alpha can also protect cells from DNA damage-induced...
Schlagworte: | PFT-alpha, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-ethanone, monohydrobromide |
Anwendung: | p53 inactivator |
CAS | 63208-82-2 |
MW: | 367.3 D |
ab 86,00 €
Artikelnummer: Cay37306-100
PK11000 is a stabilizer of mutant p53. It covalently binds to Cys182 and Cys277, increases the thermal stability, and inhibits the aggregation of the p53Y220C DNA-binding domain when used at a concentration of 1 mM. PK11000 selectively decreases the viability of mutant p53-expressing SW480 (p53R273H,P309S), NUGC-3...
Schlagworte: | 5-chloro-2-(methylsulfonyl)-4-pyrimidinecarboxylic acid |
Anwendung: | Mutant p53 stabilizer |
CAS | 38275-34-2 |
MW: | 236.6 D |
ab 104,00 €
Artikelnummer: Cay19110-1
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-kappaB with an EC50 of 0.47 µM. It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the effects on p53 and NF-kappaB and promoting cancer cell death. CBL0137 has broad...
Schlagworte: | CBLC137, Curaxin 137, 1,1'-[9-[2-[(1-methylethyl)amino]ethyl]-9H-carbazole-3,6-diyl]bis-ethanone |
Anwendung: | Curaxin, P53 activator, NF-kappaB inhibitor |
CAS | 1197996-80-7 |
MW: | 336.4 D |
ab 64,00 €
Artikelnummer: NSJ-R20404-0.1ML
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human p53 / Tumor protein 53 / TP53. Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type (PubMed:11025664,...
Schlagworte: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
737,00 €
Artikelnummer: NSJ-RQ7263
0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest,...
Schlagworte: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: A300-247A
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this...
Schlagworte: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
Anwendung: | WB, IP, IHC, ChIP-Seq, FC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: Cay9000487-5
Mutations in the p53 tumor suppressor are found in many different neoplastic cells. PRIMA-1 (Cay-63520) is a unique anti-oncogenic substance that re-activates the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes. PRIMA-1MET is a methylated derivative of PRIMA-1 that...
Schlagworte: | APR 246, 2-(hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one |
Anwendung: | Mutant p53 apoptotic function re-activator |
CAS | 5291-32-7 |
MW: | 199.3 D |
ab 92,00 €
Artikelnummer: A300-249A
Protein function: Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this...
Schlagworte: | Anti-P53, Anti-TP53, Anti-Antigen NY-CO-13, Anti-Phosphoprotein p53, Anti-Tumor suppressor p53, Anti-Cellular tumor... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €