Zu "K04443" wurden 67 Artikel gefunden!
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Zunsemetinib
Artikelnummer: Cay41863-1
Zunsemetinib is a p38alpha MAPK inhibitor biased toward MAPK-activated protein kinase 2 (MK2). It selectively inhibits p38alpha MAPK-dependent activation of MK2 over p38alpha MAPK-dependent activation of MK5, also known as p38-regulated/activated protein kinase (PRAK), and p38alpha MAPK-dependent activation of...
| Schlagworte: | ATI-450, CDD-450,... |
| Anwendung: | MK2-biased p38alpha MAPK inhibitor |
| CAS | 1640282-42-3 |
| MW: | 513.9 D |
ab 200,00 €
MK2-IN-3 hydrate
Artikelnummer: TGM-T12058-100mg
Description: MK2-IN-3 hydrate (MK-2 Inhibitor III) is an orally active, selective, and ATP-competitive inhibitor of MAPKAP-K2 (MK-2) (IC50 of 0.85 nM). Target: MAPK, ERK, MNK. Smiles: O=C1C2=C(NC(C3=CC(C4=CC5=CC=CC=C5N=C4)=NC=C3)=C2)CCN1.[H]O[H]. References: Anderson DR, et al. Pyrrolopyridine inhibitors of...
| Schlagworte: | MK-2 Inhibitor III |
| Anwendung: | Potent, cell-permeable MAPKAPK2 inhibitor |
| CAS | 1186648-22-5 |
| MW: | 358.39 D |
ab 31,00 €
PF-3644022
Artikelnummer: TGM-T16501-100mg
Description: PF-3644022 is an effective, selective, and ATP-competitive MAPKAPK2 (MK2) inhibitor (IC50: 5.2 nM and a Ki of 3 nM). PF-3644022 potently inhibits TNFalpha production and has an anti-inflammatory effect. PF-3644022 also inhibits MK3 and p38 regulated/activated kinase (PRAK) (IC50s: 53 nM and 5.0 nM,...
| Anwendung: | MAPK-activated protein kinase 2 (MK2, MAPKAPK2) inhibitor |
| CAS | 1276121-88-0 |
| MW: | 374.46 D |
ab 31,00 €
Zunsemetinib
Artikelnummer: TGM-T39126-100mg
Description: Zunsemetinib (ATI-450) is an orally active and selective inhibitor of the p38alpha mitogen-activated protein kinase-activated protein kinase 2 (MK2) pathway.Zunsemetinib is used to study spondyloarthritis and rheumatoid arthritis. Target: MAPK. Smiles:...
| Schlagworte: | CDD-450, ATI-450 |
| Anwendung: | Targets mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] (MAPKAPK2) |
| CAS | 1640282-42-3 |
| MW: | 513.92 D |
ab 281,00 €
CC-99677
Artikelnummer: TGM-T39321-100mg
Description: CC-99677 (Gamcemetinib) is a selectively targeted covalent MAPKAPK2 (MK2) inhibitor for autoimmune diseases that translates biochemical potency into cellular potency as demonstrated by potent inhibition of heat shock protein 27 (HSP1) phosphorylation in LPS-activated monocyte THP-27 cells via a...
| Schlagworte: | Gamcemetinib, CC 99677, CC99677 |
| Anwendung: | Targets mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] (MAPKAPK2) |
| CAS | 1887069-10-4 |
| MW: | 469.94 D |
ab 122,00 €
Anti-MAPKAPK2
Artikelnummer: CSB-PA070278.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Phospho-MAPKAPK2 (Ser272)
Artikelnummer: CSB-PA996185.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-MK2, Anti-phospho-MK-2, Anti-phospho-MAPKAPK2, Anti-phospho-MAPKAP-K2, Anti-phospho-MAPKAPK-2, EC=2.7.11.1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Anti-MAPKAPK2
Artikelnummer: CSB-PA511767.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAPKAPK2. Antigen Species: Human
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-MAPKAPK2 (Ab-334)
Artikelnummer: CSB-PA550963.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Anti-MAPKAPK2
Artikelnummer: CSB-PA557048.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAPKAPK2. Antigen Species: Human
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-Phospho-MAPKAPK2 (Thr334)
Artikelnummer: CSB-PA572249.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-MK2, Anti-phospho-MK-2, Anti-phospho-MAPKAPK2, Anti-phospho-MAPKAP-K2, Anti-phospho-MAPKAPK-2, EC=2.7.11.1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €
Anti-Phospho-MAPKAPK2 (Thr334)
Artikelnummer: CSB-PA583541.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-MK2, Anti-phospho-MK-2, Anti-phospho-MAPKAPK2, Anti-phospho-MAPKAP-K2, Anti-phospho-MAPKAPK-2, EC=2.7.11.1,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €