Zu "K04443" wurden 61 Artikel gefunden!
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Chemi-Verse(TM) MAPKAPK2 Kinase Assay Kit
Artikelnummer: BPS-82129
The Chemi-Verse(TM) MAPKAPK2 Kinase Assay Kit is designed to measure MAPKAPK2 kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant MAPKAPK2 kinase, kinase substrate, ATP, and kinase...
| Schlagworte: | MK2, MK-2, MAPKAPK2, MAPKAP-K2, MAPKAPK-2, EC=2.7.11.1, MAPKAP kinase 2, MAPK-activated protein kinase 2, MAP... |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
810,00 €
PF-3644022
Artikelnummer: Cay19185-1
PF-3644022 is an inhibitor of MAPK-activated protein kinase 2 (MK2, IC50 = 5.2 nM). It is selective for MK2 over MK3, MAPK-interacting protein kinase 1 (MNK-1), MNK-2, p90 ribosomal S6 kinase 1 (MSK1), MSK2, and p90 ribosomal S6 kinases 1-4 (RSK1-4, IC50s = 53, 3,000, 148, >1,000, >1,000, and >1,000 nM,...
| Schlagworte: | (10R)-9,10,11,12-tetrahydro-10-methyl-3-(6-methyl-3-pyridinyl)-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one |
| Anwendung: | MAPK-activated protein kinase 2 (MK2, MAPKAPK2) inhibitor |
| CAS | 1276121-88-0 |
| MW: | 374.5 D |
ab 48,00 €
MK2 Inhibitor III
Artikelnummer: Cay15943-5
MAP kinase-activated protein kinase 2 (MAPKAP2, MK2) is a stress-activated serine/threonine protein kinase that is phosphorylated by p38 MAP kinase and is involved in diverse cellular functions with a central role in inflammation. MK2 inhibitor III is a potent, cell-permeable inhibitor of MK2 (IC50 = 8.5 nM). It...
| Schlagworte: | 1,5,6,7-tetrahydro-2-[2-(3-quinolinyl)-4-pyridinyl]-4H-pyrrolo[3,2-c]pyridin-4-one, monohydrate |
| Anwendung: | Potent, cell-permeable MAPKAPK2 inhibitor |
| CAS | 1186648-22-5 |
| MW: | 358.4 D |
ab 98,00 €
MK2 Inhibitor IV
Artikelnummer: Cay14399-10
Activation of the p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2) pathway has been implicated in promoting pro-inflammatory cytokine production and related inflammatory diseases. MK2 inhibitor IV is a highly selective, non-ATP competitive MK2 inhibitor with an IC50 value of 0.11 µM....
| Schlagworte: | MK 25, 5-(4-chlorophenyl)-N-[4-(1-piperazinyl)phenyl]-N-(2-pyridinylmethyl)-2-furancarboxamide, monohydrochloride |
| Anwendung: | MK2 inhibitor |
| CAS | 1314118-94-9 |
| MW: | 509.4 D |
ab 109,00 €
Anti-phospho-MAPKAPK-2 (Thr334)
Artikelnummer: ARG51783.100
Protein function: Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by...
| Schlagworte: | Anti-phospho-MK2, Anti-phospho-MK-2, Anti-phospho-MAPKAPK2, Anti-phospho-MAPKAP-K2, Anti-phospho-MAPKAPK-2, EC=2.7.11.1,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
MAPKAPK2, Inactive, GST-tag
Artikelnummer: BPS-40088
Human MAPKAPK2 (MK2) (GenBank Accession No. NM_032960), full length with N-terminal GST-tag, MW= 72 kDa, expressed in a baculovirus expression system.
| Schlagworte: | MK2, MK-2, MAPKAPK2, MAPKAP-K2, MAPKAPK-2, EC=2.7.11.1, MAPKAP kinase 2, MAPK-activated protein kinase 2, MAP... |
| Anwendung: | WB standard, ELISA, SDS-PAGE, binding assays, antigen |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 72 kD |
525,00 €
MAPKAPK2, His-tag
Artikelnummer: BPS-40116
Recombinant human MAPKAPK2 (MAPK-activated protein kinase 2), also known as MK2, GenBank Accession #NM_032960, a.a. 46-end, with an N-terminal His-tag, MW = 41 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Schlagworte: | MK2, MK-2, MAPKAPK2, MAPKAP-K2, MAPKAPK-2, EC=2.7.11.1, MAPKAP kinase 2, MAPK-activated protein kinase 2, MAP... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 41 kD |
862,00 €
Anti-MAPKAP Kinase 2 (Mitogen-activated Protein Kinase...
Artikelnummer: 600-401-281
Protein function: Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | ELISA, IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rabbit, chicken, Xenopus, zebrafish |
684,00 €
Anti-MAPKAPK2
Artikelnummer: NSJ-R35113-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Mitogen-activated protein kinase-activated protein kinase 2 Protein function: Stress-activated serine/threonine-protein kinase involved in cytokines production, endocytosis, reorganization of...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | WB (transfected), ELISA (peptide), IP |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Anti-MAPKAPK2
Artikelnummer: NSJ-R36061-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Mitogen-activated protein kinase-activated protein kinase 2, MK2 Protein function: Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAP-K2, Anti-MAPKAPK-2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | WB, IP, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
755,00 €
Anti-MAPKAPK2
Artikelnummer: ARG66305.50
Protein function: Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by...
| Schlagworte: | Anti-MK2, Anti-MK-2, Anti-MAPKAPK2, Anti-MAPKAPK-2, Anti-MAPKAP-K2, EC=2.7.11.1, Anti-MAPKAP kinase 2, Anti-MAPK-activated... |
| Anwendung: | IP, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | mouse |
520,00 €
Anti-phospho-MAPKAPK-2 (Thr334)
Artikelnummer: ABE-35-1278-50
MAPKAPK-2 encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression...
| Schlagworte: | Anti-phospho-MK2, Anti-phospho-MK-2, Anti-phospho-MAPKAPK2, Anti-phospho-MAPKAPK-2, Anti-phospho-MAPKAP-K2, EC=2.7.11.1,... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
574,00 €