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SB202190
SB202190

Artikelnummer: AG-CR1-0028-M001

Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.
Schlagworte: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
Anwendung: P38 MAP kinase inhibitor
CAS 152121-30-7
MW: 331,3 D
ab 33,00 €
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SB 203580
SB 203580

Artikelnummer: Cay13067-5

Mitogen-activated protein kinases (MAPK) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Schlagworte: PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine
Anwendung: P38 MAPK inhibitor
CAS 152121-47-6
MW: 377.4 D
ab 69,00 €
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SB203580
SB203580

Artikelnummer: SYN-1074-M005

Soluble in DMSO or ethanol. SB203580 is a specific, ATP competitive, cell-permeable inhibitor of p38 MAPK with IC(50) of 0.3-0.5µM. It is 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC(50) of 3-5µM. Target: p38 , Kinase Group: CMGC , Substrate: Serine-Threonine
Schlagworte: RWJ 64809, PB 203580
Anwendung: P38 inhibitor
CAS 152121-47-6
MW: 377,4 D
ab 66,00 €
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NEU
Anti-phospho-p38alpha MAPK (Thr180/Tyr182)
Anti-phospho-p38alpha MAPK (Thr180/Tyr182)

Artikelnummer: Cay32197-100

p38 MAPK is a serine/threonine protein kinase and member of the MAPK family with roles in the regulation of immune responses and embryonic development, as well as cell differentiation, metabolism, and survival. It exists as 4 isoforms, p38alpha, -beta, -gamma, and -delta, encoded by MAPK14, MAPK11, MAPK12, and...
Schlagworte: Anti-phospho-CSBP, Anti-phospho-MAPK14, Anti-phospho-SAPK2a, Anti-phospho-MAPK 14, Anti-phospho-MAP kinase 14,...
Anwendung: IHC, WB
Reaktivität: Human
407,00 €
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SD-06
SD-06

Artikelnummer: Cay30686-10

SD-06 is an ATP-competitive inhibitor of p38alpha MAPK (IC50 = 0.016 µM). It is selective for p38alpha over p38beta, p38gamma, and p38delta MAPKs (IC50s = 0.677, >100, and >100 µM, respectively), as well as a panel of 54 additional kinases (IC50s = >3 µM for all). SD-06 inhibits LPS-induced TNF-alpha, IL-6, and...
Schlagworte: SD-006, 1-[4-[5-(4-chlorophenyl)-4-(4-pyrimidinyl)-1H-pyrazol-3-yl]-1-piperidinyl]-2-hydroxy-ethanone
Anwendung: P38alpha MAPK inhibitor
CAS 271576-80-8
MW: 397.9 D
ab 112,00 €
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Anti-Mxi 2 (N-term), clone 2F2
Anti-Mxi 2 (N-term), clone 2F2

Artikelnummer: 0046-100

Mxi2 is a splice variant of SAPK2alpha (p38). Recognizes the N-terminus of human, mouse, rat and dog p38 splice variant Mxi2.
Schlagworte: Anti-CSBP, Anti-CSBP, Anti-MAPK14, Anti-SAPK2A, Anti-MAPK 14, EC=2.7.11.24, Anti-MAP kinase 14, Anti-MAP kinase MXI2,...
Anwendung: WB, ELISA, IP
Reaktivität: Human, Mouse, Rat, Dog
293,00 €
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SB-203580
SB-203580

Artikelnummer: LKT-S0500.5

SB-203580 is an inhibitor of p38 MAPK that exhibits immunostimulatory, anticancer, and anti-fibrotic activities. In peripheral blood mononuclear cells, SB-203580 increases secretion of IFN- . In lung epithelial cells, SB-203580 inhibits TGB- 1-induced epithelial-to-mesenchymal transition (EMT). Additionally,...
Schlagworte: SB203580
Anwendung: P38 MAP kinase inhibitor
CAS 152121-47-6
MW: 377.43 D
ab 82,00 €
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SB202190
SB202190

Artikelnummer: SYN-1073-M005

Soluble in DMSO or ethanol. SB202190 is potent and selective inhibitor of the p38alpha and beta, with IC(50) values of 50 and 100nM respectively. It is a powerful regulator of LPS-induced mRNAs in monocytes. Target: p38 , Kinase Group: CMGC , Substrate: Serine-Threonine
Schlagworte: SB-202190
Anwendung: P38 alpha / beta inhibitor
CAS 152121-30-7
MW: 331,4 D
ab 66,00 €
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Anti-phospho-p38 MAPK (Thr180 / Tyr182)
Anti-phospho-p38 MAPK (Thr180 / Tyr182)

Artikelnummer: ARG52382.50

Schlagworte: Anti-phospho-Mitogen-activated protein kinase
Anwendung: IHC, WB
Reaktivität: Human, Mouse
467,00 €
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Human MAPK14 (Mitogen Activated Protein Kinase 14) CLIA Kit
Human MAPK14 (Mitogen Activated Protein Kinase 14) CLIA Kit

Artikelnummer: G-HUES00365.96

ELISA Type: CLIA. Sensitivity: 18.75 pg/mL. Range: 31.25--2000 pg/mL. Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by...
Schlagworte: CSBP, MAPK14, SAPK2a, MAPK 14, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, CSAID-binding protein,...
Anwendung: CLIA
Reaktivität: Human
629,00 €
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Human MAPK14 (Mitogen Activated Protein Kinase 14) ELISA Kit
Human MAPK14 (Mitogen Activated Protein Kinase 14) ELISA Kit

Artikelnummer: G-HUES01710.96

ELISA Type: Sandwich. Sensitivity: 0.938ng/mL. Range: 1.563--100ng/mL. Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by...
Schlagworte: CSBP, MAPK14, SAPK2a, MAPK 14, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, CSAID-binding protein,...
Anwendung: Sandwich ELISA
Reaktivität: Human
566,00 €
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SB 203580 (hydrochloride)
SB 203580 (hydrochloride)

Artikelnummer: Cay13344-5

Mitogen-activated protein kinases (MAPKs) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...
Schlagworte: PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine, monohydrochloride
Anwendung: P38 MAPK inhibitor
CAS 869185-85-3
MW: 413.9 D
ab 113,00 €
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