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Zu "K04440" wurden 210 Artikel gefunden!
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Artikelnummer: ELK-ELK5554.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MAPK9. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MAPK9. Next,...
Schlagworte: | JNK2, MAPK9, JNK-55, SAPK1a, MAPK 9, MAP kinase 9, c-Jun N-terminal kinase 2, Mitogen-activated protein kinase 9,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK0663.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human JNK. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human JNK. Next,...
Schlagworte: | MAPK8, MAPK 8, JNK-46, SAPK1c, MAP kinase 8, c-Jun N-terminal kinase 1, Stress-activated protein kinase 1c,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-EA342.100
There are three SAPK/JNK genes each of which undergoes alternative splicing, resulting in numerous isoforms. SAPK/JNK, when active as a dimer, can translocate to the nucleus and regulate transcription through its effects on c-Jun, ATF-2, and other transcription factors. Protein function: Serine/threonine-protein...
Schlagworte: | Anti-JNK2, Anti-MAPK9, Anti-SAPK1a, Anti-JNK-55, Anti-MAPK 9, Anti-MAP kinase 9, Anti-c-Jun N-terminal kinase 2,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
283,00 €
Artikelnummer: ELK-EA343.50
There are three SAPK/JNK genes each of which undergoes alternative splicing, resulting in numerous isoforms. SAPK/JNK, when active as a dimer, can translocate to the nucleus and regulate transcription through its effects on c-Jun, ATF-2, and other transcription factors. Protein function: Serine/threonine-protein...
Schlagworte: | Anti-JNK3, Anti-SAPK1b, Anti-MAPK10, Anti-MAPK 10, EC=2.7.11.24, Anti-MAP kinase 10, Anti-MAP kinase p49 3F12, Anti-c-Jun... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
169,00 €
Artikelnummer: Cay10010466-10
SP6000125 is a pan-inhibitor of JNK (IC50s = 0.04, 0.04, and 0.09 µM for JNK1, -2, and -3, respectively). It is greater than 300-fold selective for these enzymes over a panel of 17 additional kinases at 10 µM. SP6000125 reduces LPS-induced production of IL-1beta, IL-8, and TNF-alpha in isolated human peripheral...
Schlagworte: | 1PMV, NSC 75890, Pyrazolanthrone, anthra[1,9-cd]pyrazol-6(2H)-one |
Anwendung: | JNK inhibitor |
CAS | 129-56-6 |
MW: | 220.2 D |
ab 60,00 €
Artikelnummer: ARG43819.100
Protein function: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress- activated protein kinase/c-Jun N-terminal...
Schlagworte: | Anti-JNK1, Anti-MAPK8, Anti-MAPK 8, Anti-JNK-46, Anti-SAPK1c, Anti-MAPK 8, Anti-JNK-46, Anti-SAPK1c, Anti-MAP kinase 8,... |
Anwendung: | IP, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, hamster |
624,00 €
Artikelnummer: AG-CR1-3549-M001
SP600125 is an orally active, reversible and ATP-competitive broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 (IC50 = 40nM, 40nM and 90nM, respectively). In Jurkat T cells, SP600125 suppressed the phosphorylation of c-Jun with IC50 of 5-10 µM. It has 10-fold greater selectivity against MKK4, 25-fold greater...
Schlagworte: | Anthra[1-9-cd]pyrazol-6(2H)-one, 1,9-Pyrazoloanthrone, Pyrazolanthrone, NSC 75890 |
Anwendung: | Reversible, ATP-competitive JNK1/JNK2/JNK3 inhibitor |
CAS | 129-56-6 |
MW: | 220,2 D |
ab 22,00 €
Artikelnummer: NSJ-R20476-0.1ML
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. Protein function: Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical...
Schlagworte: | Anti-phospho-JNK1, Anti-phospho-MAPK8, Anti-phospho-JNK-46, Anti-phospho-MAPK 8, Anti-phospho-SAPK1c, Anti-phospho-MAP... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
737,00 €
Artikelnummer: Cay15946-5
JNK inhibitor VIII is an inhibitor of JNK1, JNK2, and JNK3 (Kis= 2, 4, and 52 nM, respectively). It is selective for JNK1, JNK2, and JNK3 over a panel of 74 kinases (Kis = >720 nM for all). It inhibits the phosphorylation of c-Jun in HepG2 cells (EC50 = 920 nM). JNK inhibitor VIII (10 µM) inhibits NGF-induced...
Schlagworte: | c-Jun N-terminal Kinase Inhibitor VIII, TCS JNK 6o, N-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy-benzeneacetamide |
Anwendung: | JNK1 / JNK2 / JNK3 inhibitor |
CAS | 894804-07-0 |
MW: | 356.4 D |
ab 135,00 €
Artikelnummer: Cay22466-1
CC-930 is an orally bioavailable and potent inhibitor of JNKs (IC50s = 61, 7, and 6 nM for JNK1, JNK2, and JNK3, respectively). It is selective for MAP kinases over a panel of 240 kinases, showing greater than 50% inhibition at only one non-MAP kinase target, EGFR (IC50 = 380 nM). Within the MAPK family, it is...
Schlagworte: | Tanzisertib, trans-4-[[9-[(3S)-tetrahydro-3-furanyl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl]amino]-cyclohexanol |
Anwendung: | JNK inhibitor |
CAS | 899805-25-5 |
MW: | 448.4 D |
ab 48,00 €
Artikelnummer: Cay18867-1
c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. CC-401 is a potent inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM). It has at least...
Schlagworte: | 3-[3-[2-(1-piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole |
Anwendung: | JNK inhibitor |
CAS | 395104-30-0 |
MW: | 388.5 D |
ab 142,00 €
Artikelnummer: Cay21482-1
Bentamapimod is an orally bioavailable inhibitor of Jun kinases (JNKs), with IC50 values for JNK1, JNK2, and JNK3 of 80, 90, and 230 nM, respectively. It is selective for JNKs over a panel of 25 related kinases. Bentamapimod induces regression of endometriotic lesions without suppressing estrogen action in animal...
Schlagworte: | AS-602801, alpha-[2-[[4-(4-morpholinylmethyl)phenyl]methoxy]-4-pyrimidinyl]-2-benzothiazoleacetonitrile |
Anwendung: | JNK1 / JNK2 / JNK3 inhibitor |
CAS | 848344-36-5 |
MW: | 457.5 D |
ab 54,00 €