Zu "K04430" wurden 79 Artikel gefunden!
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HRX215
Artikelnummer: Cay41238-1
HRX215 is an inhibitor of MAP kinase kinase 4 (MKK4, IC50 = 0. µM). It is selective for MKK4 over JNK1, B-RAF, and MKK7 (IC50s = 7. 11. and 14. µM, respectively). HRX215 (10 mg/kg) decreases hepatocyte apoptosis in a mouse model of liver damage induced by carbon tetrachloride (CCl4). It increases survival and...
| Schlagworte: | Darizmetinib, LN3348,... |
| Anwendung: | MKK4 (MAP2K4) inhibitor |
| CAS | 2369583-33-3 |
| MW: | 457.45 D |
ab 186,00 €
Anti-MKK4
Artikelnummer: A302-657A-T
Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...
| Schlagworte: | Anti-JNKK, Anti-SEK1, Anti-MEK 4, Anti-JNKK1, Anti-MAP2K4, Anti-SAPKK1, Anti-SAPKK-1, Anti-MAPKK 4, EC=2.7.12.2, Anti-SAPK... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-phospho-SEK1/MKK4 (Thr261)
Artikelnummer: ARG51672.100
Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...
| Schlagworte: | Anti-phospho-SEK1, Anti-phospho-JNKK, Anti-phospho-MEK 4, Anti-phospho-JNKK1, Anti-phospho-SAPKK1, Anti-phospho-MAP2K4,... |
| Anwendung: | ICC, IF, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-phospho-SEK1/MKK4 (Ser80)
Artikelnummer: ARG51673.100
Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...
| Schlagworte: | Anti-phospho-SEK1, Anti-phospho-JNKK, Anti-phospho-MEK 4, Anti-phospho-JNKK1, Anti-phospho-SAPKK1, Anti-phospho-MAP2K4,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 471,00 €
Anti-MKK4
Artikelnummer: A302-658A
Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...
| Schlagworte: | Anti-JNKK, Anti-SEK1, Anti-MEK 4, Anti-JNKK1, Anti-MAP2K4, Anti-SAPKK1, Anti-SAPKK-1, Anti-MAPKK 4, EC=2.7.12.2, Anti-SAPK... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-MKK4 MEK4
Artikelnummer: NSJ-R31399
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4), also called MEK4, SEK1, JNKK1 and MKK4, is an enzyme that in humans is encoded by the MAP2K4 gene. It is mapped to 17p12. This gene encodes a dual specificity protein kinase that belongs to the...
| Schlagworte: | Anti-SEK1, Anti-JNKK, Anti-JNKK1, Anti-MEK 4, Anti-SAPKK1, Anti-MAP2K4, Anti-SAPKK-1, Anti-MAPKK 4, EC=2.7.12.2, Anti-SAPK... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Vacquinol-1
Artikelnummer: Cay16321-1
Vacquinols are a new class of quinine-derivatives that stimulate death in glioblastoma cells by massive macropinocytotic vacuolization, ATP depletion, and cytoplasmic membrane rupture. A key effector of vacquinols is MAPK kinase 4 (MKK4). Vacquinol-1 is an activator of MKK4-dependent macropinocytotic cell death in...
| Schlagworte: | NSC 13316, 2-(4-chlorophenyl)-alpha-2-piperidinyl-4-quinolinemethanol |
| Anwendung: | MKK4 activator |
| CAS | 5428-80-8 |
| MW: | 352.9 D |
ab 77,00 €
Anti-Map2k4
Artikelnummer: G-PACO28138.50
Map2k4 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse, Rat, Human and for use in ELISA, WB applications. Map2k4 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Dual specificity protein kinase which acts as an essential component of the...
| Schlagworte: | Anti-SEK1, Anti-MEK 4, Anti-Jnkk1, Anti-Map2k4, Anti-JNKK 1, Anti-MAPKK 4, EC=2.7.12.2, Anti-JNK kinase 1, Anti-SAPK/ERK... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat, human |
313,00 €
Anti-MAP2K4
Artikelnummer: ATA-HPA060074.100
Protein function: Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K7/MKK7, is the one of the only known kinase to directly...
| Schlagworte: | Anti-JNKK, Anti-SEK1, Anti-JNKK1, Anti-MEK 4, Anti-MAP2K4, Anti-SAPKK1, Anti-SAPKK-1, Anti-MAPKK 4, EC=2.7.12.2, Anti-SAPK... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
MKK4, His-Tag Recombinant
Artikelnummer: BPS-101874
Recombinant human full-length MKK4 (dual-specificity mitogen-activated protein kinase kinase 4, also known as MAP2K4 or MAPKK4). This construct contains an N-terminal His-tag. The recombinant protein was affinity purified and is active.
| Schlagworte: | SEK1, JNKK, MEK 4, JNKK1, MAP2K4, SAPKK1, SAPKK-1, MAPKK 4, EC=2.7.12.2, SAPK kinase 1, SAPK/ERK kinase 1, MAPK/ERK kinase... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling, kinase assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 46 kD |
618,00 €
Anti-MEK4 (F194)
Artikelnummer: ELK-EA362.100
SAPK/Erk kinase (SEK1), also known as MEK4 or MKK4 or Jun kinase kinase (JNKK), activates the MAP kinase homologues SAPK and JNK in response to various cellular stresses and inflammatory cytokines . Activation of SEK1 occurs through MEKK phosphorylation of serine and threonine residues at positions 257 and 261,...
| Schlagworte: | Anti-JNKK, Anti-SEK1, Anti-MEK 4, Anti-JNKK1, Anti-SAPKK1, Anti-MAP2K4, Anti-SAPKK-1, Anti-MAPKK 4, EC=2.7.12.2, Anti-SAPK... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
290,00 €
Dual specificity mitogen-activated protein kinase kinase...
Artikelnummer: CSB-EP013413HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 2-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: AAPSPSGGGG SGGGSGSGTP GPVGSPAPGH PAVSSMQGKR KALKLNFANP PFKSTARFTL NPNPTGVQNP HIERLRTHSI ESSGKLKISP...
| Schlagworte: | JNKK, SEK1, MEK 4, JNKK1, MAP2K4, SAPKK1, SAPKK-1, MAPKK 4, EC=2.7.12.2, SAPK kinase 1, SAPK/ERK kinase 1, MAPK/ERK kinase... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 51.6 kD |
ab 292,00 €