Zu "K04426" wurden 79 Artikel gefunden!
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Anti-MAP3K5
Artikelnummer: ABS-KC-1426.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signaling for determination of cell fate such as differentiation and survival....
| Schlagworte: | Anti-Mitogen-activated protein kinase kinase kinase 5, Anti-Apoptosis signal-regulating kinase 1, Anti-ASK-1,... |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
GS-444217
Artikelnummer: TGM-T5190-100mg
Description: GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM). Target: ASK, Apoptosis, MAPK. Smiles: O=C(Nc1cccc(c1)-c1nncn1C1CC1)c1cc(ccn1)-n1cnc(c1)C1CC1. References: Liles JT, et al. ASK1 contributes to fibrosis and dysfunction in models of kidney...
| Schlagworte: | GS444217, GS 444217 |
| Anwendung: | AKS1 (MEKK5) inhibitor |
| CAS | 1262041-49-5 |
| MW: | 411.46 D |
ab 42,00 €
ASK1-IN-1
Artikelnummer: TGM-T9697-100mg
Description: ASK1-IN-1 is an inhibitor of apoptosis signal-regulating kinase 1 which is a key mediator in the apoptotic and inflammatory cellular stress response with an IC50 of 21 nM in biochemica assays. Target: ASK. Smiles: COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C)-c1cnccn1. References: Xin Z, et al. Discovery of...
| Anwendung: | ASK1 inhibitor |
| CAS | 2411382-24-4 |
| MW: | 405.41 D |
ab 91,00 €
TC ASK 10
Artikelnummer: TGM-T13099-100mg
Description: TC ASK 10 is a potent, selective and orally active inhibitor of apoptosis signal-regulating kinase 1 (ASK1,IC50 = 14 nM). The IC50 value for ASK2 is 0.51 µM. Target: ASK, MAPK. Smiles: Cl.Cl.CC(C)(C)c1ccc(cc1)C(=O)Nc1cn2cc(ccc2n1)-n1ccnc1. References: Terao Y, et al. Design and biological evaluation of...
| Anwendung: | ASK1 (MEKK5, MAP3K5) inhibitor |
| CAS | 1005775-56-3 |
| MW: | 432.35 D |
ab 30,00 €
NQDI-1
Artikelnummer: TGM-T3101-100mg
Description: NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 µM/500 nM). Target: Apoptosis, MAPK, ASK. Smiles: CCOC(=O)c1c2-c3ccccc3C(=O)c3cccc([nH]c1=O)c23. References: Hao H, et al. Mol Med Rep. 2016, 13(6):4585-4592.
| Schlagworte: | NQDI1, NQDI 1 |
| Anwendung: | Specific ASK1 inhibitor |
| CAS | 175026-96-7 |
| MW: | 319.31 D |
ab 42,00 €
Selonsertib
Artikelnummer: TGM-T3350-100mg
Description: Selonsertib (GS-4997) is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Target: ASK, Apoptosis, MAPK. Smiles: CC(C)n1cnnc1-c1cccc(NC(=O)c2cc(c(C)cc2F)-n2cnc(c2)C2CC2)n1. References: Lin JH,...
| Schlagworte: | GS-4997 |
| Anwendung: | Targets mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] (MAP3K5, ASK1) |
| CAS | 1448428-04-3 |
| MW: | 445.49 D |
ab 34,00 €
Anti-Phospho-MAP3K5 (Ser966)
Artikelnummer: CSB-PA009239.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-phospho-ASK1, Anti-phospho-ASK-1, Anti-phospho-MEKK 5, Anti-phospho-MAP3K5, Anti-phospho-MEK kinase 5,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, monkey |
340,00 €
Anti-Phospho-MAP3K5 (S83)
Artikelnummer: CSB-PA010179.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-ASK1, Anti-phospho-ASK-1, Anti-phospho-MEKK 5, Anti-phospho-MAP3K5, Anti-phospho-MEK kinase 5,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-MAP3K5
Artikelnummer: CSB-PA010180.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ASK1, Anti-ASK-1, Anti-MEKK 5, Anti-MAP3K5, Anti-MEK kinase 5, Anti-MAPK/ERK kinase kinase 5, Anti-Apoptosis... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-Phospho-MAP3K5 (S966)
Artikelnummer: CSB-PA000476.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-ASK1, Anti-phospho-ASK-1, Anti-phospho-MEKK 5, Anti-phospho-MAP3K5, Anti-phospho-MEK kinase 5,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-MAP3K5
Artikelnummer: CSB-PA000942.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ASK1, Anti-ASK-1, Anti-MEKK 5, Anti-MAP3K5, Anti-MEK kinase 5, Anti-MAPK/ERK kinase kinase 5, Anti-Apoptosis... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-MAP3K5 (Ab-966)
Artikelnummer: CSB-PA085364.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-ASK1, Anti-ASK-1, Anti-MEKK 5, Anti-MAP3K5, Anti-MEK kinase 5, Anti-MAPK/ERK kinase kinase 5, Anti-Apoptosis... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
283,00 €