Zu "K04419" wurden 19 Artikel gefunden!
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MLK3, GST-tag
Artikelnummer: BPS-41104
Human MLK3, also known as Mixed Lineage Kinase 3, Mitogen-activated protein kinase kinase kinase 11, MAP3K11, PTK1, SPRK, and MGC17114, GenBank Accession No. NM_002419, a.a. 1-488, with N-terminal GST-tag, MW = 83 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Schlagworte: | EC=2.7.11.25, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3 domain-containing... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 83 kD |
862,00 €
Anti-MAP3K11
Artikelnummer: E-AB-16612.120
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
URMC-099
Artikelnummer: SYN-1211-M001
Solid. Soluble in DMSO or water. Inhibition of mixed lineage kinase 3 (MLK-3) is a potential strategy for the treatment of Parkinson's disease and HIV-1 associated neuro-cognitive disorders (HAND), requiring an inhibitor that can achieve significant brain concentration levels. URMC-099 is an orally bioavailable...
| Schlagworte: | 3-(1H-Indol-5-yl)-5-(4-(4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3- b]pyridine |
| Anwendung: | MLK-3 inhibitor |
| CAS | 1229582-33-5 |
| MW: | 421,5 D |
ab 132,00 €
Anti-MAP3K11
Artikelnummer: E-AB-91482.120
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3 domain-containing... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 198,00 €
Anti-phospho-MLK3 (Ser674)
Artikelnummer: ELK-ES1535.100
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Anti-phospho-Mixed lineage kinase 3, Anti-phospho-Mitogen-activated protein kinase kinase kinase 11,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Anti-phospho-MLK3 (Thr277+Ser281)
Artikelnummer: ELK-ES20162.100
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Anti-phospho-Mixed lineage kinase 3, Anti-phospho-Mitogen-activated protein kinase kinase kinase 11,... |
| Anwendung: | WB, ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Anti-MLK3
Artikelnummer: ELK-ES6252.100
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
URMC-099
Artikelnummer: Cay19147-5
URMC-099 is an orally bioavailable, brain-penetrant inhibitor of mixed-lineage kinases (MLKs) with IC50 values of 19, 42, 14, and 150 nM for MLK1, MLK2, MLK3, and the related MLK family member DLK, respectively. It also inhibits LRRK2 activity with an IC50 value of 11 nM. In vitro, URMC-099 has been shown to reduce...
| Schlagworte: | 3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine |
| Anwendung: | MLK inhibitor |
| CAS | 1229582-33-5 |
| MW: | 421.5 D |
ab 81,00 €
Anti-MLK3 (Ab-674)
Artikelnummer: ABD-8B8375.50
Custom conjugation services for this antibody as available (eg. labeling of Anti-MLK3 (Ab-674) with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE,...
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
601,00 €
MAP3K11, Human mitogen-activated protein kinase kinase...
Artikelnummer: VHPS-5527
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | MLK3, MAP3K11, EC=2.7.11.25, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3... |
| Anwendung: | RNA quantification |
43,00 €
Map3K11, Mouse mitogen-activated protein kinase kinase...
Artikelnummer: VMPS-3685
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Mlk3, Map3k11, EC=2.7.11.25, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11 |
| Anwendung: | RNA quantification |
43,00 €
Anti-MAP3K11 (MAP3K11, MLK3, PTK1, SPRK,...
Artikelnummer: 031103.100
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | Anti-MLK3, Anti-MAP3K11, EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase... |
| Anwendung: | ELISA, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
728,00 €