Zu "K04419" wurden 40 Artikel gefunden!
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NEU
Anti-Recombinant MLK3, clone C372924
Artikelnummer: E-AN303304L.100
Protein function: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and...
| Schlagworte: | Anti-MAP3K11, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | WB, ICC/IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 171,00 €
MLK3, GST-tag
Artikelnummer: BPS-41104
Human MLK3, also known as Mixed Lineage Kinase 3, Mitogen-activated protein kinase kinase kinase 11, MAP3K11, PTK1, SPRK, and MGC17114, GenBank Accession No. NM_002419, a.a. 1-488, with N-terminal GST-tag, MW = 83 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Schlagworte: | EC=2.7.11.25, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3 domain-containing... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 83 kD |
901,00 €
Anti-MAP3K11
Artikelnummer: E-AB-16612.120
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and...
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
URMC-099
Artikelnummer: SYN-1211-M001
Solid. Soluble in DMSO or water. Inhibition of mixed lineage kinase 3 (MLK-3) is a potential strategy for the treatment of Parkinson's disease and HIV-1 associated neuro-cognitive disorders (HAND), requiring an inhibitor that can achieve significant brain concentration levels. URMC-099 is an orally bioavailable...
| Schlagworte: | 3-(1H-Indol-5-yl)-5-(4-(4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3- b]pyridine |
| Anwendung: | MLK-3 inhibitor |
| CAS | 1229582-33-5 |
| MW: | 421,5 D |
ab 154,00 €
Anti-MAP3K11
Artikelnummer: CSB-PA01469A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MAP3K11. Antigen Species: Human
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | ELISA, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-Phospho-MAP3K11 (S674)
Artikelnummer: CSB-PA000754.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | EC=2.7.11.25, Anti-phospho-Mixed lineage kinase 3, Anti-phospho-Mitogen-activated protein kinase kinase kinase 11,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-MAP3K11
Artikelnummer: CSB-PA092285.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAP3K11. Antigen Species: Human
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-MAP3K11
Artikelnummer: CSB-PA791051.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MAP3K11. Antigen Species: Human
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
MLK3 Inhibitor
Artikelnummer: Cay42887-1
An MLK3 inhibitor (IC50 = 50 = 15.5 µM). Formulation: A neat solid. InChI: InChI=1S/C20H16F6N4O2S/c1-33(31,32)15-4-2-3-12(9-15)10-27-17-16(20(24,25)26)11-28-18(30-17)29-14-7-5-13(6-8-14)19(21,22)23/h2-9,11H,10H2,1H3,(H2,27,28,29,30). InChIKey: WXTXWVIOZYHNDG-UHFFFAOYSA-N. SMILES:...
| Schlagworte: | Mixed-lineage Kinase 3 Inhibitor, Mixed-lineage Kinase 3 Inhibitor 1, Mixed-lineage Kinase 3-IN-1, MLK3 Inhibitor 1,... |
| Anwendung: | MLK3 (MAP3K11) inhibitor |
| MW: | 490.42 D |
ab 70,00 €
Anti-MAP3K11
Artikelnummer: ATA-HPA045774.100
Rabbit Polyclonal MAP3K11 Antibody against Human mitogen-activated protein kinase kinase kinase 11. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs:...
| Schlagworte: | EC=2.7.11.25, Anti-Mixed lineage kinase 3, Anti-Mitogen-activated protein kinase kinase kinase 11, Anti-Src-homology 3... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
NEU
Human, MLK3 cDNA ORF Clone, N-HA tag
Artikelnummer: SNB-HG11067-NY
Protein Function: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and...
| Schlagworte: | MAP3K11, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3 domain-containing... |
| Spezies-Reaktivität: | human |
326,00 €
NEU
Human, MLK3 cDNA ORF Clone, C-HA tag
Artikelnummer: SNB-HG11067-CY
Protein Function: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and...
| Schlagworte: | MAP3K11, Mixed lineage kinase 3, Mitogen-activated protein kinase kinase kinase 11, Src-homology 3 domain-containing... |
| Spezies-Reaktivität: | human |
326,00 €