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NG 25 (hydrochloride hydrate)
NG 25 (hydrochloride hydrate)

Artikelnummer: Cay27579-1

NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively). It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38alpha (IC50s = 56.4, 82.3, and 102 nM,...
Schlagworte: N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-benzamide,...
Anwendung: TAK1 (MAP3K7) inhibitor, MAP4K2 (GCK) inhibitor
MW: 647 D
ab 73,00 €
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GCK (MAP4K2), GST-tag
GCK (MAP4K2), GST-tag

Artikelnummer: BPS-40107

Human GCK, also known as MAP4K2, GenBank Accession No. NM_004579, full length, with N-terminal GST tag, MW ~125 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Schlagworte: GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,...
Anwendung: Enzyme kinetics, inhibitor screening, selectivity profiling
Exprimiert in: insect cells
Ursprungsart: human
MW: 125 kD
862,00 €
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Anti-MAP4K2
Anti-MAP4K2

Artikelnummer: E-AB-10897.120

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
Schlagworte: Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,...
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 71,00 €
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GNF-7
GNF-7

Artikelnummer: Cay19918-1

GNF-7 is a multi-kinase inhibitor (IC50s = 25, 8, 61, 122, 136, and 133 nM for ACK1, GCK, Bcr-AblT315I, Bcr-AblE255V, Bcr-AblG250E, and c-Abl, respectively). It also inhibits several additional kinases in a panel by greater than 50% when used at a concentration of 10 µM. GNF-7 inhibits the growth of Ba/F3 cells...
Schlagworte: N-[3-[1,4-dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trif...
Anwendung: Ack1 / GCK inhibitor
CAS 839706-07-9
MW: 547.5 D
ab 43,00 €
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Anti-MAP4K2
Anti-MAP4K2

Artikelnummer: E-AB-14677.120

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
Schlagworte: Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,...
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 71,00 €
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Anti-MAP4K2
Anti-MAP4K2

Artikelnummer: G-CAB17524.100

Protein function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser...
Schlagworte: Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 352,00 €
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Anti-MAP4K2
Anti-MAP4K2

Artikelnummer: ATA-HPA007330.100

Protein function: Serine/threonine-protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Acts as a MAPK kinase kinase kinase (MAP4K) and is an upstream activator of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway and to a lesser...
Schlagworte: Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,...
Anwendung: ICC, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
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MAP4K2 protein (His tag), recombinant human
MAP4K2 protein (His tag), recombinant human

Artikelnummer: E-PDEH100398.100

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Human MAP4K2 protein (Q12851-2) (Ile 501-Tyr 812) was expressed with a N-His&C-His. Sequence: Ile 501-Tyr 812. Fusion tag: N-His & C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 35 kDa. Protein...
Schlagworte: GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,...
Exprimiert in: E.coli
Ursprungsart: human
MW: 34.21 kD
ab 81,00 €
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Anti-MAP4K2
Anti-MAP4K2

Artikelnummer: E-AB-91806.120

The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha,...
Schlagworte: GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 198,00 €
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-10 %
Rabattaktion
Anti-M4K2
Anti-M4K2

Artikelnummer: ELK-ES10541.100

mitogen-activated protein kinase kinase kinase kinase 2(MAP4K2) Homo sapiens The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may...
Schlagworte: Anti-GCK, Anti-MAP4K2, Anti-MEKKK 2, Anti-GC kinase, EC=2.7.11.1, Anti-MEK kinase kinase 2, Anti-Germinal center kinase,...
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, rat, mouse,
169,00 € ab 152,10 €
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MAP4K2, Human mitogen-activated protein kinase kinase kinase kinase 2, Real Time PCR Primer Set
MAP4K2, Human mitogen-activated protein kinase kinase...

Artikelnummer: VHPS-5537

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: GCK, MAP4K2, MEKKK 2, GC kinase, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein,...
Anwendung: RNA quantification
43,00 €
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Map4K2, Mouse mitogen-activated protein kinase kinase kinase kinase 2, Real Time PCR Primer Set
Map4K2, Mouse mitogen-activated protein kinase kinase...

Artikelnummer: VMPS-3694

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Schlagworte: GCK, Map4k2, Rab8ip, MEKKK 2, EC=2.7.11.1, MEK kinase kinase 2, Germinal center kinase, Rab8-interacting protein, MAPK/ERK...
Anwendung: RNA quantification
43,00 €
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