Zu "K04412" wurden 42 Artikel gefunden!
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XMU-MP-1
Artikelnummer: Cay22083-1
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...
| Schlagworte: | 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-benzenesulfonamide |
| Anwendung: | STK3 / STK4 inhibitor |
| CAS | 2061980-01-4 |
| MW: | 416.5 D |
ab 38,00 €
Anti-MST2/STK3
Artikelnummer: A300-467A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-KRS1, Anti-STK3, EC=2.7.11.1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
586,00 €
Anti-MST1-2/STK3-4
Artikelnummer: A300-468A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-KRS1, Anti-STK3, EC=2.7.11.1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
STK3(MST2), active human recombinant protein, GST-tag
Artikelnummer: BPS-40013
Human STK3 (serine/threonine kinase 3), also known as MST-2 (Mammalian STE20-like protein kinase 2) or KRS1, GenBank Accession No. NM_006281, amino acids 2-492(end), with N-terminal GST-tag, MW=78.4 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | KRS1, STK3, EC=2.7.11.1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 78.4 kD |
536,00 €
Anti-MST2
Artikelnummer: NSJ-R33439-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Serine/threonine kinase 3, STK3 Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by...
| Schlagworte: | Anti-STK3, Anti-KRS1, EC=2.7.11.1, MST2 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
836,00 €
Anti-MST1,2/STK3,4 (IHC)
Artikelnummer: IHC-00432
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-KRS1, Anti-STK3, EC=2.7.11.1 |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-STK3 / MST2
Artikelnummer: ARG41791.100
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-STK3, Anti-KRS1, EC=2.7.11.1 |
| Anwendung: | IHC (paraffin), IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Anti-MST2 / STK3
Artikelnummer: NSJ-RQ5765
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the...
| Schlagworte: | Anti-STK3, Anti-KRS1, EC=2.7.11.1, MST2 Antibody / STK3 |
| Anwendung: | WB, IHC (paraffin), FC, IF, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey |
790,00 €
Anti-STK3
Artikelnummer: ATA-HPA007120.100
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-STK3, Anti-KRS1, EC=2.7.11.1 |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 330,00 €
Anti-MST2/STK3
Artikelnummer: A300-467A-T
MST2/STK3 is a member of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include...
| Schlagworte: | Anti-STK3, Anti-KRS1, EC=2.7.11.1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
165,00 €
Anti-Phospho-STK3/STK4 (T183)
Artikelnummer: CSB-PA050174.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-KRS1, Anti-phospho-STK3, EC=2.7.11.1, STK3, KRS1, MST2, Serine/threonine-protein kinase 3, Mammalian... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Anti-STK3 Recombinant Monoclonal, clone 3C3
Artikelnummer: CSB-RA980100A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: STK3. Antigen Species: Human
| Schlagworte: | Anti-KRS1, Anti-STK3, EC=2.7.11.1, Serine/threonine-protein kinase 3 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 2)... |
| Anwendung: | ELISA, WB, |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €