Zu "K04411" wurden 47 Artikel gefunden!
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Anti-Recombinant Krs-2, clone 9D2
Artikelnummer: E-AN301176L.100
STK3(serine/threonine kinase 3) Homo sapiens This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is...
| Schlagworte: | Anti-STK4, Anti-STE20-like kinase MST1, Anti-Serine/threonine-protein kinase 4, Anti-Serine/threonine-protein kinase... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-MST1 / Mammalian STE20-like protein kinase 1 / STK4
Artikelnummer: NSJ-FY12975
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. MST1 antibody detects Mammalian STE20-like protein kinase 1, a serine/threonine kinase that functions as a central regulator of apoptosis, stress signaling, and organ size control. The UniProt recommended name is Serine/threonine-protein...
| Schlagworte: | Anti-STK4, Anti-STE20-like kinase MST1, Anti-Serine/threonine-protein kinase 4, Anti-Mammalian STE20-like protein kinase... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-phospho-MST1/MST2 (Thr183/Thr180), clone 32S47
Artikelnummer: NSJ-FY12170
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-MST1/MST2 (Thr183/Thr180) antibody detects the phosphorylated forms of MST1 (Thr183) and MST2 (Thr180), two core kinases in the Hippo signaling pathway. MST1 and MST2 are serine/threonine...
| Schlagworte: | Anti-phospho-STK4, Anti-phospho-STE20-like kinase MST1, Anti-phospho-Serine/threonine-protein kinase 4,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
IHMT-MST1-58
Artikelnummer: Cay43664-1
IHMT-MST1-58 is an inhibitor of mammalian Ste20-like protein kinase 1 (MST1, IC50 = 23 nM). It is selective for MST1 over MST2 and NIMA-related kinase 3 (NEK3, IC50s = 652 and >10,000 nM, respectively). IHMT-MST1-58 (50 mg/kg per day) reduces fasting blood glucose levels in mice in models of type 1- or type 2...
| Schlagworte: | 4-[[5,6,7,8-tetrahydro-5,8-dimethyl-7-(2-methylphenyl)-6-oxo-2-pteridinyl]amino]-benzenesulfonamide |
| Anwendung: | MST1 inhibitor |
| CAS | 2414484-25-4 |
| MW: | 438.51 D |
ab 85,00 €
Anti-MST1/STK4
Artikelnummer: A300-465A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-STK4, Anti-KRS2, EC=2.7.11.1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
586,00 €
Anti-MST1-2/STK3-4
Artikelnummer: A300-466A
Protein function: Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by...
| Schlagworte: | Anti-STK4, Anti-KRS2, EC=2.7.11.1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
XMU-MP-1
Artikelnummer: Cay22083-25
XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2 (IC50s = 71.1 and 38.1 nM, respectively). It is selective for MST1 and 2 over a panel of 468 kinases at a concentration of 1 µM. XMU-MP-1 inhibits phosphorylation of MOB1, LATS1 and 2, and YAP in HepG2 cells as well as MST1 and 2...
| Schlagworte: | 4-[(6,10-dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]-benzenesulfonamide |
| Anwendung: | STK3 / STK4 inhibitor |
| CAS | 2061980-01-4 |
| MW: | 416.5 D |
ab 40,00 €
XMU-MP-1
Artikelnummer: TGM-T4212-2mg
Description: XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2. Target: Hippo pathway. Smiles: CN1c2ccsc2C(=O)N(C)c2cnc(Nc3ccc(cc3)S(N)(=O)=O)nc12. References: Fan F, et al. Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration. Sci Transl Med....
| Anwendung: | STK3 / STK4 inhibitor |
| CAS | 2061980-01-4 |
| MW: | 416.48 D |
ab 46,00 €
STK4(MST1), active human recombinant protein, GST-tag
Artikelnummer: BPS-40017
Human STK4 (serine/threonine kinase 4), also known as MST-1 (Mammalian STE20-like protein kinase 1) or KRS2, GenBank Accession No. NM_006282, amino acids 2-488(end), with N-terminal GST-tag, MW=81.5 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | STK4, KRS2, EC=2.7.11.1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Baculovirus |
| Ursprungsart: | human |
| MW: | 81.5 kD |
536,00 €
Anti-STK3/STK4
Artikelnummer: E-AB-13112.120
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...
| Schlagworte: | Anti-KRS2, Anti-STK4, EC=2.7.11.1, STK3/STK4 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-MST1 (Mammalian STE20-like protein kinase 1)
Artikelnummer: NSJ-F50888-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A...
| Schlagworte: | Anti-STK4, Anti-KRS2, EC=2.7.11.1, MST1 Antibody (Mammalian STE20-like protein kinase 1) |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-STK3/STK4
Artikelnummer: E-AB-16302.120
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK...
| Schlagworte: | Anti-KRS2, Anti-STK4, EC=2.7.11.1, STK3/STK4 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €