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Zu "K04409" wurden 104 Artikel gefunden!
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Artikelnummer: TGM-TMPH-02091-100ug
Description: PAK1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
Schlagworte: | p21-activated kinase 1, Serine/threonine-protein kinase PAK 1, PAK1, p65-PAK, Alpha-PAK |
MW: | 76.6 kD |
ab 198,00 €
Artikelnummer: TGM-T6546-100mg
Description: IPA-3 is a selective, non-ATP competitive Pak1 inhibitor with an IC50 of 2.5 µM, and it does not inhibit group II PAKs (PAKs 4-6). Target: PAK. Smiles: Oc1ccc2ccccc2c1SSc1c(O)ccc2ccccc12. References: Deacon SW, et al. Chem Biol, 2008, 15(4), 322-331.
Schlagworte: | IPA 3, IPA3 |
Anwendung: | PAK1 inhibitor |
CAS | 42521-82-4 |
MW: | 350.45 D |
ab 40,00 €
Artikelnummer: TGM-T6840-2mg
Description: FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively. Target: PAK. Smiles: C(C)N1C=2C(C=C(C1=O)C3=C(Cl)C=C(Cl)C=C3)=CN=C(NC4=CC(F)=C(C=C4)N5CCNCC5)N2. References: Hayashi-Takagi A, et al. Proc Natl Acad Sci U S A....
Anwendung: | PAK1 / PAK2 / PAK3 inhibitor |
CAS | 1232030-35-1 |
MW: | 513.39 D |
ab 37,00 €
Artikelnummer: A301-259A
Protein function: Protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. Can directly...
Schlagworte: | Anti-PAK1, Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, EC=2.7.11.1, Anti-p21-activated kinase 1,... |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Artikelnummer: TGM-T16367-100mg
Description: NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM). Target: PAK. Smiles: CC(C)NC(=O)N1CC[C@@H](C1)NC1=Nc2cc(F)ccc2N(CC(F)F)c2ccc(Cl)cc12. References: Karpov AS, et al. Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor. ACS Med Chem...
Anwendung: | Allosteric PAK1 inhibitor |
CAS | 1783816-74-9 |
MW: | 479.93 D |
ab 45,00 €
Artikelnummer: TGM-T35928-1mg
Description: NVS-PAK1-1 is a potent allosteric inhibitor of PAK1 with an IC 50 of 5 nM for dephosphorylated PAK1 and 6 nM for phosphorylated PAK1 as assessed. Inhibition is ATP-competitive, most likely due to indirect competition due to incompatibility of ATP binding with the DFG-out binding conformation of the...
Schlagworte: | NVS-PAK1-C |
Anwendung: | Negative control |
CAS | 2250019-95-3 |
MW: | 465.9 D |
77,00 €
Artikelnummer: TGM-T6839-100mg
Description: FRAX-1036 is a effective and selective PAK1 inhibitor. Target: PAK. Smiles: CCn1c2nc(NCCC3CCN(C)CC3)ncc2cc(-c2ccc(cc2Cl)-c2cncc(C)n2)c1=O. References: Ong CC, et al. Breast Cancer Res. 2015, 17:59.
Anwendung: | Potent, selective PAK1 inhibitor |
CAS | 1432908-05-8 |
MW: | 518.05 D |
ab 46,00 €
Artikelnummer: CSB-PA003703.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1, ADRB2... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA020203.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-phospho-PAK-1, Anti-phospho-p65-PAK, Anti-phospho-Alpha-PAK, Anti-phospho-p21-activated kinase 1,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Artikelnummer: CSB-PA020205.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-phospho-PAK-1, Anti-phospho-p65-PAK, Anti-phospho-Alpha-PAK, Anti-phospho-p21-activated kinase 1,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Artikelnummer: CSB-PA020209.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1, ADRB2... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Artikelnummer: CSB-PA020215.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-PAK-1, Anti-p65-PAK, Anti-Alpha-PAK, Anti-p21-activated kinase 1, Anti-Serine/threonine-protein kinase PAK 1, PAK1,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
126,00 €