Zu "K04393" wurden 51 Artikel gefunden!
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Anti-Active Cdc42, monoclonal
Artikelnummer: NB-26905
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the...
| Schlagworte: | Anti-CDC42, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog |
| Anwendung: | IP, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
717,00 €
Human CDC42 (Cell Division Cycle Protein 42) ELISA Kit
Artikelnummer: ELK-ELK4504.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CDC42. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CDC42. Next,...
| Schlagworte: | G25K GTP-binding protein, Cell division control protein 42 homolog |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-CDC42
Artikelnummer: ARG43921.50
Protein function: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle...
| Schlagworte: | Anti-G25K GTP-binding protein, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog {ECO:0000305},... |
| Anwendung: | ELISA, FC, ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
520,00 €
ML-141
Artikelnummer: Cay18496-1
Cdc42 is a member of the Rho GTPase subfamily that has roles in cytoskeleton organization, cell cycle progression, signal transduction, and vesicle trafficking. It cycles between a GTP-bound active state and a GDP-bound inactive state. ML-141 is a noncompetitive, allosteric inhibitor of Cdc42 (EC50 = 2.1 µM) with no...
| Schlagworte: | CID2950007, 4-[4,5-dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]-benzenesulfonamide |
| Anwendung: | Allosteric Cdc42 inhibitor |
| CAS | 71203-35-5 |
| MW: | 407.5 D |
ab 43,00 €
CASIN
Artikelnummer: Cay17694-50
The Rho family of GTPases regulates diverse signal transduction pathways. One member, the cell division control protein 42 homolog (Cdc42), is involved in filopodia function, cell polarity, cell cycling, and other processes. CASIN is an indole-based small molecule that inhibits activation of the Cdc42 GTPase (IC50 =...
| Schlagworte: | Pirl1-related Compound 2, 2-[(2,3,4,9-tetrahydro-6-phenyl-1H-carbazol-1-yl)amino]-ethanol |
| Anwendung: | Cdc42 GTPase activation inhibitor |
| CAS | 425399-05-9 |
| MW: | 306.4 D |
ab 43,00 €
ZCL 278
Artikelnummer: Cay14849-5
ZCL 278 is a cell-permeable inhibitor of Cdc42, a Rho family GTPase. It binds into the surface groove on Cdc42 (Kd = 6.4-11.4 µM), blocking interaction with intersectin (ITSN), a guanine nucleotide exchange factor (GEF). It inhibits Cdc42-mediated microspike formation and neuronal branching in 3T3 fibroblast and...
| Schlagworte: | 2-(4-bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]-acetamide |
| Anwendung: | Cdc42 inhibitor |
| CAS | 587841-73-4 |
| MW: | 584.9 D |
ab 64,00 €
CID-44216842
Artikelnummer: Cay37775-1
CID-44216842 is a cell division cycle 42 (Cdc42) inhibitor. It inhibits GTP binding to wild-type Cdc42 and the constitutively active mutant Cdc42Q61L (EC50s = 0.3 and 0.5 µM, respectively).Formal Name: 4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide. CAS Number: 1222513-26-9....
| Schlagworte: | 4-[5-(4-bromophenyl)-4,5-dihydro-3-(3-methoxyphenyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Anwendung: | Cdc42 inhibitor |
| CAS | 1222513-26-9 |
| MW: | 486.4 D |
ab 54,00 €
MLS-573151
Artikelnummer: Cay15269-1
The Rho family of GTPases regulates diverse signal transduction pathways. One member, the cell division control protein 42 homolog (Cdc42), is involved in filopodia function, cell polarity, cell cycling, and other processes. MLS-573151 is a specific, cell permeable inhibitor of Cdc42 (IC50 = 2 µM). It has no effect...
| Schlagworte: | 4-(4,5-dihydro-3,5-diphenyl-1H-pyrazol-1-yl)-benzenesulfonamide |
| Anwendung: | Cdc42 inhibitor |
| CAS | 10179-57-4 |
| MW: | 377.5 D |
ab 60,00 €
MBQ-167
Artikelnummer: Cay35437-5
MBQ-167 is a dual inhibitor of Rac and cell division cycle 42 (Cdc42, IC50s = 103 and 78 nM, respectively). It reduces Rac and Cdc42 GTP binding and GTPase activity and limits migration and mammosphere formation in MDA-MB-231 breast cancer cells when used at a concentration of 250 nM. MBQ-167 (250 nM), alone and in...
| Schlagworte: | 9-ethyl-3-(5-phenyl-1H-1,2,3-triazol-1-yl)-9H-carbazole |
| Anwendung: | Rac / Cdc42 dual inhibitor |
| CAS | 2097938-73-1 |
| MW: | 338.4 D |
ab 40,00 €
Human CDC42 ELISA Kit
Artikelnummer: G-HUFI00623.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-CDC42
Artikelnummer: 200-901-AJ3
Anti-CDC42 Antibody is an IgY fraction antibody purified from monospecific chicken egg yolks by a multi-step process which includes selective precipitation and salt fractionation followed by extensive dialysis against the buffer stated above. Cross reactivity with CDC42 from other sources has not been determined....
| Schlagworte: | Anti-CDC42, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog |
| Anwendung: | ELISA, WB |
| Wirt: | Chicken |
| Spezies-Reaktivität: | human, mouse, rat |
684,00 €
Anti-CDC42
Artikelnummer: NSJ-R30435
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cell division control protein 42 homolog also known as CDC42 is a protein involved in regulation of the cell cycle. In humans, CDC42 is encoded by the CDC42 gene. CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control...
| Schlagworte: | Anti-CDC42, Anti-G25K GTP-binding protein, Anti-Cell division control protein 42 homolog, CDC42 Antibody |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, mouse, rat |
755,00 €