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Zu "K04385" wurden 38 Artikel gefunden!
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Artikelnummer: Cay13659-5
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to beta-catenin activation of gene transcription. IWR-1-endo is a potent inhibitor of the...
Schlagworte: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide |
Anwendung: | Wnt response inhibitor |
CAS | 1127442-82-3 |
MW: | 409.4 D |
ab 92,00 €
Artikelnummer: CSB-EP897472HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 745-843aa. Protein Length: Partial. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: EDHKEPKKLA GVHALQASEL VVTYFFCGEE IPYRRMLKAQ SLTLGHFKEQ LSKKGNYRYY FKKASDEFAC GAVFEEIWED ETVLPMYEGR ILGKVERID. Purity: Greater than 90% as determined by...
Schlagworte: | Axil, AXIN2, Axin-2, Conductin, Axin-like protein, Axis inhibition protein 2, Recombinant Human Axin-2 (AXIN2), partial |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 18.4 kD |
ab 247,00 €
Artikelnummer: CSB-PA577711.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: AXIN2. Antigen Species: Human
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2, Axil antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: CSB-PA917071.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: AXIN2. Antigen Species: Human
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2, Axil antibody,... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Artikelnummer: Cay13598-10
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to beta-catenin activation of gene transcription. IWR-1-exo is a diastereomer of...
Schlagworte: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinyl-benzamide |
Anwendung: | IWR-1-endo control |
CAS | 1127442-87-8 |
MW: | 409.4 D |
ab 92,00 €
Artikelnummer: NSJ-F49172-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The Axin-related protein, Axin2, presumably plays an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway, like its rodent homologs, mouse conductin/rat axil. In mouse, conductin organizes a multiprotein complex of APC (adenomatous...
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2, AXIN2 Antibody |
Anwendung: | WB, IHC, FC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 350,00 €
Artikelnummer: ARG56270.100
Protein function: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B. [The UniProt Consortium]
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2 |
Anwendung: | WB, ICC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
658,00 €
Artikelnummer: G-HUFI02130.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: G-MOFI00661.96
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
694,00 €
Artikelnummer: ARG58116.50
Protein function: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B. [The UniProt Consortium]
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2 |
Anwendung: | ICC, IF, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse, rat |
567,00 €
Artikelnummer: AG-CR1-3581-M005
Synthetic. Potent and reversible cell permeable Wnt pathway signaling inhibitor. Inhibits Wnt-induced accumulation of beta-catenin, leading to proteasomal degradation of this protein through a destruction complex which consists of Apc, Axin2, CK1 and GSK-3beta. Stabilizes the destruction complex, increasing the...
Schlagworte: | 4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
Anwendung: | Potent, reversible cell permeable Wnt pathway signaling inhibitor |
CAS | 1127442-82-3 |
MW: | 409,4 D |
88,00 €
Artikelnummer: ARG58774.100
Protein function: Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B. [The UniProt Consortium]
Schlagworte: | Anti-Axil, Anti-AXIN2, Anti-Axin-2, Anti-Conductin, Anti-Axin-like protein, Anti-Axis inhibition protein 2 |
Anwendung: | ICC, IF, IHC (paraffin), WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
658,00 €