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Human RPS6Ka1 (Ribosomal Protein S6 Kinase Alpha 1) ELISA Kit
Human RPS6Ka1 (Ribosomal Protein S6 Kinase Alpha 1) ELISA...

Artikelnummer: ELK-ELK7155.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RPS6Ka1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RPS6Ka1....
Schlagworte: RSK-1, p90S6K, RPS6KA1, p90RSK1, p90-RSK 1, MAPKAPK1A, MAPKAPK-1a, S6K-alpha-1, EC=2.7.11.1, MAPKAP kinase 1a, Ribosomal...
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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BI-D1870
BI-D1870

Artikelnummer: Cay15264-1

The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-D1870 is a cell permeable, ATP-competitive inhibitor of the four vertebrate isoforms of RSK, RSK1-4 (IC50s = 31, 24, 18, and 15 nM, respectively). At 100...
Schlagworte: 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-6(5H)-pteridinone
Anwendung: RSK1/2/3/4 inhibitor
CAS 501437-28-1
MW: 391.4 D
ab 76,00 €
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SL 0101-1
SL 0101-1

Artikelnummer: Cay11704-1

The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. SL 0101-1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 value of 89 nM (Ki = 1 µM) without interfering with upstream...
Schlagworte: 3-[(3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Anwendung: RSK2 inhibitor
CAS 77307-50-7
MW: 516.5 D
ab 77,00 €
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LJH685
LJH685

Artikelnummer: Cay19913-10

LJH685 is an inhibitor of p90 ribosomal S6 kinases (RSKs, also known as MAP kinase-activated protein kinases, or MAPKAPKs) that inhibits RSK1, 2, and 3 in vitro with IC50 values of 6, 5, and 4 nM, respectively. It is selective for RSKs over a panel of 96 other kinases. LJH685 blocks RSK activity in cells, preventing...
Schlagworte: 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-phenol
Anwendung: RSK inhibitor
CAS 1627710-50-2
MW: 381.4 D
ab 43,00 €
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BIX 02565
BIX 02565

Artikelnummer: Cay19183-1

The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. Phosphorylation of the sodium-hydrogen exchanger (NHE) in cardiac tissue by RSK has been shown to activate NHE during cellular stresses, such as myocardial...
Schlagworte: (5R)-N-[1-[3-(dimethylamino)propyl]-1H-benzimidazol-2-yl]-2,3,4,5-tetrahydro-5-methyl-1-oxo-1H-[1,4]diazepino[1,2-a]indole...
Anwendung: RSK2 inhibitor
CAS 1311367-27-7
MW: 458.6 D
ab 48,00 €
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LJI308
LJI308

Artikelnummer: Cay19924-1

LJI308 is a selective and potent inhibitor of the p90 ribosomal S6 kinase (RSK) family with IC50 values ranging from 4 to 13 nM for RSK isoforms 1-3. In a panel of 442 kinases, LJI308 is selective for RSK1, RSK3, and RSK4. It also inhibits S6K1, MEK4, and HIP in the low micromolar range but had no effect on other...
Schlagworte: 2,6-difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]-phenol
Anwendung: RSK inhibitor
CAS 1627709-94-7
MW: 368.4 D
ab 60,00 €
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BRD7389
BRD7389

Artikelnummer: Cay20214-5

BRD7389 is an inhibitor of ribosomal S6 kinases (RSKs, IC50s = 1.5, 2.4, and 1.2 µM for RSK1, RSK2, and RSK3, respectively). Through this action, BRD7389 causes mouse alphaTC1 pancreatic alpha cells to adopt several morphological and gene expression features of beta cells, including increased insulin expression....
Schlagworte: 1-[(2-phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione
Anwendung: RSK1 / RSK2 / RSK3 inhibitor
CAS 376382-11-5
MW: 366.4 D
ab 44,00 €
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FMK
FMK

Artikelnummer: Cay9000887-5

FMK is an inhibitor of p90 ribosomal S6 kinase 3alpha (RSK2, IC50 = 15 nM). It inhibits the C-terminal domain (CTD) kinase activity of RSK2 and inhibits EGF-induced phosphorylation of RSK2 Ser386 in serum-starved COS-7 cells (EC50 = ~200 nM). FMK (6 µM) reduces invasion, but not proliferation, of M4e, 212LN, and 37B...
Schlagworte: Fluoromethyl Ketone, Fluoromethyl Ketone-MEA, FMK-MEA,...
Anwendung: RSK2 inhibitor
CAS 821794-92-7
MW: 342.4 D
ab 60,00 €
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Anti-phospho-p90 RSK (Thr348)
Anti-phospho-p90 RSK (Thr348)

Artikelnummer: ARG51607.100

Protein function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular...
Schlagworte: Anti-phospho-RSK-1, Anti-phospho-p90S6K, Anti-phospho-RPS6KA1, Anti-phospho-p90RSK1, Anti-phospho-p90-RSK 1,...
Anwendung: ICC, IF, IHC (paraffin), WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 436,00 €
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Anti-phospho-p90 RSK (Ser352)
Anti-phospho-p90 RSK (Ser352)

Artikelnummer: ARG51615.100

Protein function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular...
Schlagworte: Anti-phospho-RSK-1, Anti-phospho-p90S6K, Anti-phospho-RPS6KA1, Anti-phospho-p90RSK1, Anti-phospho-p90-RSK 1,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 436,00 €
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Anti-p90 RSK, clone 6B9-D6-F8
Anti-p90 RSK, clone 6B9-D6-F8

Artikelnummer: ARG55903.100

Protein function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular...
Schlagworte: Anti-RSK-1, Anti-p90S6K, Anti-p90RSK1, Anti-RPS6KA1, Anti-MAPKAPK1A, Anti-p90-RSK 1, Anti-MAPKAPK-1a, EC=2.7.11.1,...
Anwendung: WB, IP
Wirt: Mouse
Spezies-Reaktivität: human, mouse, monkey
624,00 €
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Anti-RSK1
Anti-RSK1

Artikelnummer: A302-458A

Protein function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular...
Schlagworte: Anti-RSK-1, Anti-p90S6K, Anti-RPS6KA1, Anti-p90RSK1, Anti-MAPKAPK1A, Anti-p90-RSK 1, Anti-MAPKAPK-1a, Anti-S6K-alpha-1,...
Anwendung: WB, IP, IHC-IF
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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