Zu "K04373" wurden 212 Artikel gefunden!
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Anti-Recombinant RSK2, clone 9F1
Artikelnummer: E-AN300651L.100
RPS6KA3(ribosomal protein S6 kinase A3) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling...
| Schlagworte: | Anti-RPS6KA3, Anti-pp90RSK2, Anti-Ribosomal S6 kinase 2, Anti-Insulin-stimulated protein kinase 1, Anti-Ribosomal protein... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant Phospho-p90RSK (Ser380), clone 2D8
Artikelnummer: E-AN300836L.100
Ribosomal protein S6 kinase A1(RPS6KA1) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling...
| Schlagworte: | Anti-RPS6KA1, Anti-Ribosomal S6 kinase 1, Anti-Ribosomal protein S6 kinase alpha-1, Anti-90 kDa ribosomal protein S6... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant Phospho-p90RSK(Thr359, Ser363), clone 9B8
Artikelnummer: E-AN300870L.100
ribosomal protein S6 kinase A1(RPS6KA1) Homo sapiens This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling...
| Schlagworte: | Anti-RPS6KA1, Anti-Ribosomal S6 kinase 1, Anti-Ribosomal protein S6 kinase alpha-1, Anti-90 kDa ribosomal protein S6... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant RSK3, clone 2D5
Artikelnummer: E-AN301245L.100
ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated...
| Schlagworte: | Anti-RPS6KA2, Anti-pp90RSK3, Anti-Ribosomal S6 kinase 3, Anti-Ribosomal protein S6 kinase alpha-2, Anti-90 kDa ribosomal... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-RPS6KA3 / Ribosomal protein S6 kinase alpha-3
Artikelnummer: NSJ-FY12518
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. RPS6KA3 antibody detects Ribosomal protein S6 kinase alpha-3, a serine/threonine kinase that functions as a key effector in the MAPK signaling pathway. Also known as p90RSK2, this kinase transmits signals from extracellular stimuli to regulate...
| Schlagworte: | Anti-RPS6KA3, Anti-pp90RSK2, Anti-Ribosomal S6 kinase 2, Anti-Insulin-stimulated protein kinase 1, Anti-Ribosomal protein... |
| Anwendung: | WB, ICC, IF, IP, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-Phospho-p90RSK (Thr359, Ser363) Monoclonal...
Artikelnummer: E-AN300156L.100
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 1 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been...
| Schlagworte: | RSK-1, p90S6K, RPS6KA1, p90RSK1, p90-RSK 1, MAPKAPK1A, MAPKAPK-1a, EC=2.7.11.1, S6K-alpha-1, MAPKAP kinase 1a, Ribosomal... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 182,00 €
BI-D1870
Artikelnummer: Cay15264-1
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-D1870 is a cell permeable, ATP-competitive inhibitor of the four vertebrate isoforms of RSK, RSK1-4 (IC50s = 31, 24, 18, and 15 nM, respectively). At 100...
| Schlagworte: | 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-7,8-dihydro-5,7-dimethyl-8-(3-methylbutyl)-6(5H)-pteridinone |
| Anwendung: | RSK1/2/3/4 inhibitor |
| CAS | 501437-28-1 |
| MW: | 391.4 D |
ab 84,00 €
SL 0101-1
Artikelnummer: Cay11704-1
The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. SL 0101-1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 value of 89 nM (Ki = 1 µM) without interfering with upstream...
| Schlagworte: | 3-[(3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | RSK2 inhibitor |
| CAS | 77307-50-7 |
| MW: | 516.5 D |
ab 85,00 €
LJH685
Artikelnummer: Cay19913-10
LJH685 is an inhibitor of p90 ribosomal S6 kinases (RSKs, also known as MAP kinase-activated protein kinases, or MAPKAPKs) that inhibits RSK1, 2, and 3 in vitro with IC50 values of 6, 5, and 4 nM, respectively. It is selective for RSKs over a panel of 96 other kinases. LJH685 blocks RSK activity in cells, preventing...
| Schlagworte: | 2,6-difluoro-4-[4-[4-(4-methyl-1-piperazinyl)phenyl]-3-pyridinyl]-phenol |
| Anwendung: | RSK inhibitor |
| CAS | 1627710-50-2 |
| MW: | 381.4 D |
ab 49,00 €
BIX 02565
Artikelnummer: Cay19183-1
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. Phosphorylation of the sodium-hydrogen exchanger (NHE) in cardiac tissue by RSK has been shown to activate NHE during cellular stresses, such as myocardial...
| Schlagworte: | (5R)-N-[1-[3-(dimethylamino)propyl]-1H-benzimidazol-2-yl]-2,3,4,5-tetrahydro-5-methyl-1-oxo-1H-[1,4]diazepino[1,2-a]indole... |
| Anwendung: | RSK2 inhibitor |
| CAS | 1311367-27-7 |
| MW: | 458.6 D |
ab 54,00 €
LJI308
Artikelnummer: Cay19924-1
LJI308 is a selective and potent inhibitor of the p90 ribosomal S6 kinase (RSK) family with IC50 values ranging from 4 to 13 nM for RSK isoforms 1-3. In a panel of 442 kinases, LJI308 is selective for RSK1, RSK3, and RSK4. It also inhibits S6K1, MEK4, and HIP in the low micromolar range but had no effect on other...
| Schlagworte: | 2,6-difluoro-4-[4-[4-(4-morpholinyl)phenyl]-3-pyridinyl]-phenol |
| Anwendung: | RSK inhibitor |
| CAS | 1627709-94-7 |
| MW: | 368.4 D |
ab 67,00 €
BRD7389
Artikelnummer: Cay20214-5
BRD7389 is an inhibitor of ribosomal S6 kinases (RSKs, IC50s = 1.5, 2.4, and 1.2 µM for RSK1, RSK2, and RSK3, respectively). Through this action, BRD7389 causes mouse alphaTC1 pancreatic alpha cells to adopt several morphological and gene expression features of beta cells, including increased insulin expression....
| Schlagworte: | 1-[(2-phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione |
| Anwendung: | RSK1 / RSK2 / RSK3 inhibitor |
| CAS | 376382-11-5 |
| MW: | 366.4 D |
ab 50,00 €