Zu "K04373" wurden 201 Artikel gefunden!
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Anti-RPS6KA1
Artikelnummer: ABS-KC-6183.100
Protein function: Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular...
| Schlagworte: | Anti-Ribosomal protein S6 kinase alpha-1, Anti-S6K-alpha-1, Anti-90 kDa ribosomal protein S6 kinase 1, Anti-p90-RSK 1,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, monkey |
ab 232,00 €
BRD7389
Artikelnummer: TGM-T14779-100mg
Description: BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 µM, 2.4 µM, and 1.2 µM for RSK1, RSK2, and RSK3, respectively. Target: FLT, DAPK, SGK, CDK, Pim, S6 Kinase. Smiles: O=C1c2ccccc2-c2c(NCCc3ccccc3)c(=O)[nH]c3cccc1c23. References: Park YS, et al. EGFR and PKC are involved in the...
| Anwendung: | RSK1 / RSK2 / RSK3 inhibitor |
| CAS | 376382-11-5 |
| MW: | 366.41 D |
ab 46,00 €
SL 0101-1
Artikelnummer: TGM-T16896-10mg
Description: SL 0101-1 (SL0101) is a selective, efficient, reversible and ATP-competitive inhibitor of p90 ribosomal S6 kinase (RSK) that can permeate cell membranes, with an IC50 value of 89 nM for RSK.SL 0101-1 (SL0101) is also a potent RSK1/2 inhibitor with a Ki value of 1 µM. SL 0101-1 (SL0101) is also a potent...
| Schlagworte: | SL0101 |
| Anwendung: | RSK2 inhibitor |
| CAS | 77307-50-7 |
| MW: | 516.45 D |
ab 142,00 €
BIX 02565
Artikelnummer: TGM-T5428-10mg
Description: BIX 02565 is a potent inhibitor of ribosomal S6 kinase 2 (RSK2, IC50: 1.1 nM). Target: LRRK2, S6 Kinase. Smiles: C[C@@H]1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C. References: Kirrane TM, et al. Indole RSK inhibitors. Part 2: optimization of cell potency and kinase selectivity. Bioorg Med...
| Anwendung: | RSK2 inhibitor |
| CAS | 1311367-27-7 |
| MW: | 458.56 D |
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LJH685
Artikelnummer: TGM-T6877-100mg
Description: LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM). Target: S6 Kinase, Apoptosis. Smiles: CN1CCN(CC1)c1ccc(cc1)-c1ccncc1-c1cc(F)c(O)c(F)c1. References: Aronchik I, et al. Mol Cancer Res. 2014, 12(5), 803-812.
| Anwendung: | RSK inhibitor |
| CAS | 1627710-50-2 |
| MW: | 381.42 D |
ab 31,00 €
LJI308
Artikelnummer: TGM-T6878-100mg
Description: LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively. Target: S6 Kinase. Smiles: Oc1c(F)cc(cc1F)-c1cnccc1-c1ccc(cc1)N1CCOCC1. References: Aronchik I, et al. Mol Cancer Res. 2014, 12(5), 803-812.
| Anwendung: | RSK inhibitor |
| CAS | 1627709-94-7 |
| MW: | 368.38 D |
ab 40,00 €
RSK4 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04357-50ug
Description: Ribosomal protein S6 kinase alpha-6, also known as Ribosomal S6 kinase 4, 9 kDa ribosomal protein S6 kinase 6,RSK-4, RSK4 and RPS6KA6, is a protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein kinase family and S6 kinase subfamily. RPS6KA6 contains one AGC-kinase C-terminal domain...
| Schlagworte: | PP90RSK4, ribosomal protein S6 kinase, 90kDa, polypeptide 6, RSK4 |
| MW: | 110 kD |
497,00 €
RSK3 Protein, Human, Recombinant (GST)
Artikelnummer: TGM-TMPY-04392-50ug
Description: Ribosomal protein S6 kinase alpha-2, also known as 9 kDa ribosomal protein S6 kinase 2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, Ribosomal S6 kinase 3, RSK-3, RPS6KA2 and MAPKAPK1C, is a nucleus protein that belongs to the protein kinase superfamily, AGC Ser/Thr protein...
| Schlagworte: | RSK3, MAPKAPK1C, p90-RSK3, S6K-alpha2, S6K-alpha, HU-2, RSK, pp90RSK3, S6K-alpha2, S6K-alpha, ribosomal protein S6 kinase,... |
| MW: | 110 kD |
497,00 €
FMK
Artikelnummer: TGM-TQ0310-100mg
Description: FMK is an irreversible inhibitor of RSK2 kinase. Target: S6 Kinase. Smiles: Cc1ccc(cc1)-c1c(C(=O)CF)n(CCCO)c2ncnc(N)c12. References: Cuello F, et al. Evidence for direct regulation of myocardial Na+/H+ exchanger isoform 1 phosphorylation and activity by 90-kDa ribosomal S6 kinase (RSK): effects of the...
| Anwendung: | RSK2 inhibitor |
| CAS | 821794-92-7 |
| MW: | 342.37 D |
ab 67,00 €
RMM-46
Artikelnummer: TGM-T26103-100mg
Description: RMM-46 is a reversible and selective covalent inhibitor for MSK/RSK-family kinases. Target: Others. Smiles: C(=C(C(NC(CO)(C)C)=O)C#N)C=1C=C2C(=NNC2=CC1)C3=CC(OC)=C(OC)C(OC)=C3. References: Miller RM, Paavilainen VO, Krishnan S, Serafimova IM, Taunton J. Electrophilic fragment-based design of reversible...
| Anwendung: | RSK2 inhibitor |
| CAS | 1307896-46-3 |
| MW: | 450.49 D |
ab 1.520,00 €
BI-D1870
Artikelnummer: TGM-T6171-100mg
Description: BI-D1870 is a cell-permeable, ATP-competitive inhibitor of ribosomal S6 kinases (RSKs, IC50s: 31/24/18/15 nM for RSK1/2/3/4). Target: S6 Kinase, Autophagy. Smiles: CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12. References: Sapkota GP, et al. BI-D1870 is a specific inhibitor of the p90 RSK...
| Anwendung: | RSK1/2/3/4 inhibitor |
| CAS | 501437-28-1 |
| MW: | 391.42 D |
ab 48,00 €
Anti-RPS6KA1
Artikelnummer: CSB-PA004034.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-RSK-1, Anti-p90S6K, Anti-RPS6KA1, Anti-p90RSK1, Anti-MAPKAPK1A, Anti-p90-RSK 1, Anti-MAPKAPK-1a, Anti-S6K-alpha-1,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €