Zu "K04372" wurden 68 Artikel gefunden!
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DS12881479
Artikelnummer: Cay44121-1
DS12881479 is an inhibitor of MAP kinase-interacting serine/threonine protein kinase 1 (MNK1, IC50s = 21 and 416 nM for the inactive and active forms, respectively). It is selective for MNK1 over 46 other kinases but does inhibit FMS-related tyrosine kinase 3 (FLT3) and dual-specificity tyrosine...
| Schlagworte: | 1-methyl-N-(5-phenyl-2-thiazolyl)-4-piperidinecarboxamide |
| Anwendung: | MNK1 (MKNK1) inhibitor |
| CAS | 2373065-59-7 |
| MW: | 301.41 D |
ab 172,00 €
Anti-MKNK1
Artikelnummer: ATA-HPA034867.100
Rabbit Polyclonal MKNK1 Antibody against Human MAPK interacting serine/threonine kinase 1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000028708: 84%,...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
CGP 57380
Artikelnummer: Cay13322-5
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1) in vitro (IC50 = 2.2 µM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. It blocks the phosphorylation of eIF4E in response to TNF-alpha, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 =...
| Schlagworte: | MNK1 Inhibitor, N3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine |
| Anwendung: | MAPK-interacting kinase 1 inhibitor |
| CAS | 522629-08-9 |
| MW: | 244.2 D |
ab 67,00 €
MNK1 (5385D), active human recombinant protein
Artikelnummer: BPS-40078
Active human MNK (T385D, amino acids 2nd-End (deletion 165-205aa)) (GenBank Accession No. NM_003684), with N-terminal GST tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | MNK1, Mnk1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 74 kD |
536,00 €
MNK2, GST-tag
Artikelnummer: BPS-40128
Recombinant human MNK2 (MAP kinase interacting serine/threonine kinase 2), also known as GPRK7 (G protein-coupled receptor kinase 7), GenBank Accession No. NM_017572, full length, with N-terminal GST tag, MW ~74 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | Mnk2, GPRK7, MKNK2, EC=2.7.11.1, MAPK signal-integrating kinase 2, MAP kinase signal-integrating kinase 2, MAP... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 74 kD |
901,00 €
Anti-Mknk2, NT (Mknk2, Mnk2, MAP kinase-interacting...
Artikelnummer: 038455.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended...
| Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
865,00 €
MNK1 Kinase Assay Kit
Artikelnummer: BPS-78032
The MNK1 Kinase Assay Kit is designed to measure MNK1 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.
| Schlagworte: | MAPK-interacting serine/threonine-protein kinase 1 kit, |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
2.632,00 €
Anti-MKNK2 (PACO02788)
Artikelnummer: G-PACO02788.50
MKNK2 Antibody from Assay Genie with reactivity against Human, Mouse, Rat and for use in ELISA, WB applications. MKNK2 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the...
| Schlagworte: | Anti-Mnk2, Anti-MKNK2, Anti-GPRK7, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
225,00 €
Anti-MKNK2
Artikelnummer: ATA-HPA021875.100
Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA...
| Schlagworte: | Anti-Mnk2, Anti-GPRK7, Anti-MKNK2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-MKNK1
Artikelnummer: ATA-HPA071293.100
Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium...
| Schlagworte: | Anti-MNK1, Anti-Mnk1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-MKNK2
Artikelnummer: ATA-HPA070499.100
Protein function: Serine/threonine-protein kinase that phosphorylates SFPQ/PSF, HNRNPA1 and EIF4E. May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA...
| Schlagworte: | Anti-Mnk2, Anti-GPRK7, Anti-MKNK2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
MAP kinase-interacting serine/threonine-protein kinase 1...
Artikelnummer: CSB-EP861139HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-465aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MVSSQKLEKP IEMGSSEPLP IADGDRRRKK KRRGRATDSL PGKFEDMYKL TSELLGEGAY AKVQGAVSLQ NGKEYAVKII EKQAGHSRSR VFREVETLYQ CQGNKNILEL IEFFEDDTRF YLVFEKLQGG...
| Schlagworte: | Mnk1, MNK1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 58.2 kD |
ab 292,00 €