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Zu "K04372" wurden 45 Artikel gefunden!
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Artikelnummer: Cay13322-5
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1) in vitro (IC50 = 2.2 µM), with no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. It blocks the phosphorylation of eIF4E in response to TNF-alpha, arsenite, anisomycin, PMA, or fetal calf serum in 293 cells (IC50 =...
Schlagworte: | MNK1 Inhibitor, N3-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine |
Anwendung: | MAPK-interacting kinase 1 inhibitor |
CAS | 522629-08-9 |
MW: | 244.2 D |
ab 60,00 €
Artikelnummer: BPS-40078
Active human MNK (T385D, amino acids 2nd-End (deletion 165-205aa)) (GenBank Accession No. NM_003684), with N-terminal GST tag, MW=74 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
Schlagworte: | MNK1, Mnk1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 74 kD |
525,00 €
Artikelnummer: BPS-40128
Recombinant human MNK2 (MAP kinase interacting serine/threonine kinase 2), also known as GPRK7 (G protein-coupled receptor kinase 7), GenBank Accession No. NM_017572, full length, with N-terminal GST tag, MW ~74 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Schlagworte: | Mnk2, GPRK7, MKNK2, EC=2.7.11.1, MAPK signal-integrating kinase 2, MAP kinase signal-integrating kinase 2, MAP... |
Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
Exprimiert in: | insect cells |
Ursprungsart: | human |
MW: | 74 kD |
862,00 €
Artikelnummer: 038455-APC.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, FLISA, Recommended...
Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
993,00 €
Artikelnummer: 038455-Biotin.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended...
Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
993,00 €
Artikelnummer: 038455-FITC.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, FLISA, Recommended...
Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
Anwendung: | FLISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
993,00 €
Artikelnummer: 038455-HRP.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended...
Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
993,00 €
Artikelnummer: 038455.200
Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended...
Schlagworte: | Anti-Mnk2, Anti-Mknk2, EC=2.7.11.1, Anti-MAPK signal-integrating kinase 2, Anti-MAP kinase signal-integrating kinase 2,... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
728,00 €
Artikelnummer: BPS-78032
The MNK1 Kinase Assay Kit is designed to measure MNK1 kinase activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.
Schlagworte: | MAPK-interacting serine/threonine-protein kinase 1 kit, |
Anwendung: | Enzyme kinetics, drug discovery, HTS |
Spezies-Reaktivität: | human |
2.518,00 €
Artikelnummer: G-CBCAB01650.96
MNK1 (Phospho-Thr255) Colorimetric Cell-Based ELISA Kit Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. [The UniProt Consortium]
Schlagworte: | MNK1, Mnk1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
Anwendung: | In-cell ELISA |
641,00 €
Artikelnummer: G-CBCAB01684.96
MNK1 (Phospho-Thr385) Colorimetric Cell-Based ELISA Kit Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. [The UniProt Consortium]
Schlagworte: | MNK1, Mnk1, MKNK1, MAPK signal-integrating kinase 1, MAP kinase signal-integrating kinase 1, MAP kinase-interacting... |
Anwendung: | In-cell ELISA |
641,00 €
Artikelnummer: G-CAB18429.100
Protein function: May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine- containing mRNA cap. [The UniProt Consortium]
Schlagworte: | Anti-Mnk1, Anti-MNK1, Anti-MKNK1, Anti-MAPK signal-integrating kinase 1, Anti-MAP kinase signal-integrating kinase 1,... |
Anwendung: | WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €