Zu "K04371" wurden 343 Artikel gefunden!
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Anti-MAPK3
Artikelnummer: ABS-KC-4086.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Schlagworte: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 206,00 €
Anti-MAPK3
Artikelnummer: ABS-KC-4213.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Schlagworte: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 206,00 €
Anti-MAPK3
Artikelnummer: ABS-KC-4219.100
Protein function: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF....
| Schlagworte: | Anti-Mitogen-activated protein kinase 3, Anti-MAP kinase 3, Anti-MAPK 3, Anti-ERT2, Anti-Extracellular signal-regulated... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, mouse |
ab 206,00 €
Anti-ERK 1/2
Artikelnummer: E-D-AB-10257L.100
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases,also known as extracellular signal-regulated kinases (ERKs),act in a signaling cascade that regulates various cellular processes such as proliferation,differentiation,and cell cycle progression in response to a variety of...
| Schlagworte: | Anti-ERT2, Anti-MNK1, Anti-Erk1, Anti-Mapk3, Anti-ERK-1, Anti-MAPK 3, Anti-p44-MAPK, Anti-p44-ERK1, EC=2.7.11.24, Anti-MAP... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 109,00 €
SCH 772984
Artikelnummer: Cay19166-1
The extracellular regulated kinases 1 and 2 (ERK1/2) are functionally redundant kinases activated by a variety of growth factors and mitogens. SCH 772984 is a potent inhibitor of ERK1 and ERK2 (IC50s = 4 and 1 nM, respectively). It is highly selective, with only seven kinases of 300 tested showing more than 50%...
| Schlagworte: | (3R)-1-[2-oxo-2-[4-[4-(2-pyrimidinyl)phenyl]-1-piperazinyl]ethyl]-N-[3-(4-pyridinyl)-1H-indazol-5-yl]-3-pyrrolidinecarboxa... |
| Anwendung: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.7 D |
ab 52,00 €
SCH772984
Artikelnummer: TGM-T6066-2mg
Description: SCH772984 is an ERK inhibitor that inhibits ERK1 and ERK2 (IC50=4/1 nM) and is highly selective and ATP-competitive. SCH772984 exhibits antitumor activity against BRAF or RAS mutant cells. Target: MEK, ERK. Smiles: O=C(CN1CC[C@H](C1)C(=O)Nc1ccc2[nH]nc(-c3ccncc3)c2c1)N1CCN(CC1)c1ccc(cc1)-c1ncccn1....
| Anwendung: | Potent ERK1 / ERK2 inhibitor |
| CAS | 942183-80-4 |
| MW: | 587.67 D |
ab 48,00 €
Ulixertinib
Artikelnummer: TGM-T7005-100mg
Description: Ulixertinib (VRT752271) (BVD-523, VRT752271) is an effective and reversible ERK1/ERK2 inhibitor. The IC50 of Ulixertinib is less than 0.3 nM for ERK2. Target: ERK. Smiles: CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c(Cl)cn1. References: Ward RA, et al. J Med Chem. 2015, 58(11), 4790-4801.
| Schlagworte: | VRT752271, BVD-523 |
| Anwendung: | Targets mitogen-activated protein kinase 1/3 [EC:2.7.11.24] (ERK, MAPK1_3) |
| CAS | 869886-67-9 |
| MW: | 433.33 D |
ab 34,00 €
Ulixertinib hydrochloride
Artikelnummer: TGM-T7005L-2mg
Description: Ulixertinib is an inhibitor of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal...
| Schlagworte: | BVD 523, VRT752271, VRT 752271, BVD523, Ulixertinib HCl, BVD-523 |
| Anwendung: | ERK1/ERK2 inhibitor |
| CAS | 1956366-10-1 |
| MW: | 469.79 D |
46,00 €
ERK Inhibitor II (Negative control)
Artikelnummer: TGM-T71316-100mg
Description: ERK Inhibitor II (Negative control) effectively blocks extracellular signal-regulated kinase (ERK) activity and interferes with insulin receptor activation, serving as a valuable tool in diabetes research. Target: Others. Smiles: O=C1C2=CC(C=3C(=NN4C3C=CC=C4)C5=CC=CC=C5)=NN=C2NN1
| Anwendung: | ERK inhibitor |
| CAS | 1177970-73-8 |
| MW: | 328.33 D |
ab 1.820,00 €
ERK1/2 inhibitor 9
Artikelnummer: TGM-T78190-50mg
Description: ERK1/2 Inhibitor 9 (Probe 1), a covalent antagonist of ERK1/2, exhibits sub-micromolar efficacy in cellular assays (A375 GI50=0.47 µM) and facilitates the reduction of phospho-ERK1/2 levels. When conjugated with trans-cyclo-octene (TCO) and Tz-Thalidomide (tetrazine-tagged Thalidomide), it forms the...
| Anwendung: | ERK1/2 inhibitor |
| CAS | 2169302-75-2 |
| MW: | 586.08 D |
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ERK1/2 inhibitor 3
Artikelnummer: TGM-T74373-50mg
Description: ERK1/2 Inhibitor 3, a potent inhibitor of ERK1/2, plays a crucial role in the signal transduction pathway by targeting the Mitogen-activated protein kinase (MAPK) family, specifically the extracellular signal-regulated kinase (ERK). Given its significant impact, this compound holds promise for research...
| Anwendung: | ERK1/2 inhibitor |
| CAS | 2737294-99-2 |
| MW: | 620.09 D |
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ERK1/2 inhibitor 4
Artikelnummer: TGM-T74374-50mg
Description: ERK1/2 Inhibitor 5, a potent suppressant of the ERK1/2 pathway, is instrumental in the mitogen-activated protein kinase (MAPK) signal transduction pathway, where extracellular signal-regulated kinase (ERK) serves as a critical component of the MAPK family. This compound holds promise for the...
| Anwendung: | ERK1/2 inhibitor |
| CAS | 2490396-99-9 |
| MW: | 604.09 D |
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