Zu "K04365" wurden 215 Artikel gefunden!
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Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-MSM2-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Nucleus. Cytoplasm. Cell membrane. Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. Positive Control: A431, Jurkat or HeLa cells. Human melanoma or colon carcinoma. Chromosome Location: 7q34. Protein Function: Protein...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-RBM7-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm. Positive Control: A431, Jurkat or HeLa cells. Human melanoma, brain, testis or colon carcinoma. Chromosome Location: 7q34. Protein Function: Protein kinase involved in the transduction of mitogenic signals from the cell...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-RBM7-P1ABX
Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cytoplasm. Positive Control: A431, Jurkat or HeLa cells. Human melanoma, brain, testis or colon carcinoma. Chromosome Location: 7q34. Protein Function: Protein kinase involved in the transduction of mitogenic signals from the cell...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
704,00 €
Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-MSM1-P0
Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cytoplasm. Positive Control: A431, Jurkat and HeLa cells. Human melanoma and colon carcinoma, Human Skeletal Muscles. Chromosome Location: 7q34. Protein Function: Protein kinase involved in the transduction of mitogenic signals from the...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | ELISA, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 326,00 €
Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-MSM1-P1ABX
Formulation: Purified Ab WITHOUT BSA at 1.0mg/ml. Cellular Localization: Cytoplasm. Positive Control: A431, Jurkat and HeLa cells. Human melanoma and colon carcinoma, Human Skeletal Muscles. Chromosome Location: 7q34. Protein Function: Protein kinase involved in the transduction of mitogenic signals from the cell...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | ELISA, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €
Anti-BRAF (V600E Mutant Specific) (Prognostic Marker),...
Artikelnummer: NEO-673-MSM2-P1ABX
Formulation: Purified Ab WITHOUT BSA at 1.0mg/ml. Cellular Localization: Nucleus. Cytoplasm. Cell membrane. Colocalizes with RGS14 and RAF1 in both the cytoplasm and membranes. Positive Control: A431, Jurkat or HeLa cells. Human melanoma or colon carcinoma. Chromosome Location: 7q34. Protein Function: Protein kinase...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf, Anti-v-Raf murine sarcoma... |
| Anwendung: | ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
704,00 €
CFT-1946
Artikelnummer: Cay44277-1
CFT-1946 is a degrader of the mutant B-RAF isoforms B-RAFV600E, B-RAFG469A, and B-RAFG466V. InChI:...
| Schlagworte: | Tagarafdeg |
| Anwendung: | B-RAFV600E / B-RAFG469A / B-RAFG466V degrader |
| CAS | 2882165-79-7 |
| MW: | 958.01 D |
ab 464,00 €
Anti-B-Raf (V600E), monoclonal
Artikelnummer: NB-26039
Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in...
| Schlagworte: | Anti-p94, Anti-BRAF, Anti-BRAF1, EC=2.7.11.1, Anti-Proto-oncogene B-Raf, Anti-Serine/threonine-protein kinase B-raf,... |
| Anwendung: | ELISA, WB, IHC, IP |
| Wirt: | Mouse |
746,00 €
PLX4032
Artikelnummer: Cay10618-5
PLX4032 is an orally bioavailable, ATP-competitive inhibitor of mutant V600E and wild type B-Raf kinases (IC50s = 31 and 100 nM, respectively). It inhibits cell proliferation in a variety of cell lines expressing B-Raf V600E and synergizes strongly with taxol, vinblastine, and oxaliplatin in inhibiting the...
| Schlagworte: | RG-7204, Ro 51-85426, Vemurafenib,... |
| Anwendung: | B-Raf kinase (mutant V600E and wild type) inhibitor |
| CAS | 918504-65-1 |
| MW: | 489.9 D |
ab 69,00 €
BRAF (V600E), human recombinant protein (GST-His-Tag)
Artikelnummer: BPS-40533
Human v-raf murine sarcoma viral oncogene homolog B1 (BRAF), GenBank Accession No. NM_004333, a.a. 417-end with Val-to-Glu mutation on a.a. 600 and N-terminal GST tag, MW=69 kDa, expressed in Sf9 insect cells via a baculovirus expression system. This mutation is often cited as V599E.
| Schlagworte: | p94, BRAF1, Proto-oncogene B-Raf, Serine/threonine-protein kinase B-raf, v-Raf murine sarcoma viral oncogene homolog B1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 69 kD |
536,00 €
PLX4720
Artikelnummer: Cay15142-1
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. Mutations in the kinase B-Raf are involved in a wide range of cancers. In particular, the mutation B-RafV600E occurs in melanomas and thyroid cancer but is poorly targeted by many inhibitors of...
| Schlagworte: | Raf Kinase Inhibitor V, N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide |
| Anwendung: | BRAFV600E inhibitor |
| CAS | 918505-84-7 |
| MW: | 413.8 D |
ab 69,00 €
Encorafenib
Artikelnummer: Cay16994-1
B-Raf is a MAP kinase kinase kinase, which functions downstream of Ras family GTPases to activate MEK1/2 and ERK1/2 signaling. A mutation of B-Raf in exon 15 at codon 600 where a valine is substituted by glutamic acid (V600E) has been linked to melanoma. Encorafenib is a selective inhibitor of B-RafV600E mutant...
| Schlagworte: | LGX818,... |
| Anwendung: | B-Raf V600E mutant inhibitor |
| CAS | 1269440-17-6 |
| MW: | 540 D |
ab 58,00 €