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Zu "K04363" wurden 239 Artikel gefunden!
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Artikelnummer: NSJ-RQ5478
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The PDGFRA gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a...
Schlagworte: | Anti-CD140a, Anti-PDGFR2, Anti-PDGFRA, Anti-PDGFR-2, Anti-PDGFR-alpha, EC=2.7.10.1, Anti-PDGF-R-alpha, Anti-CD140a... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK5831.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PDGFRa. Next,...
Schlagworte: | CD140a, Pdgfra, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140 antigen-like family member A, Platelet-derived growth factor... |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK2768.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDGFRa....
Schlagworte: | CD140a, PDGFR2, PDGFRA, PDGFR-2, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
365,00 €
ab 328,50 €
Artikelnummer: ARG43854.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an...
Schlagworte: | Anti-PDGFRA, Anti-PDGFR2, Anti-CD140a, Anti-CD140a, Anti-PDGFR-2, Anti-PDGFR-2, Anti-PDGFR-alpha, Anti-PDGFR-alpha,... |
Anwendung: | FC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
696,00 €
Artikelnummer: Cay37754-25
Seralutinib is an inhibitor of PDGFR, c-Kit, and colony stimulating factor 1 receptor (CSF1R). It inhibits PDGF-BB-induced phosphorylation of ERK in PDGFRalpha-dependent H1703 human lung epithelial cells, human pulmonary arterial smooth muscle cells (HPASMCs), which express PDGFRalpha and PDGFRbeta, and human lung...
Schlagworte: | GB002, PK 10571, N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)-2-pyrazinyl]amino]ethyl]phenyl]-5-methyl-3-pyridinecarboxamide |
Anwendung: | PDGFR / c-Kit / CSF1R inhibitor |
CAS | 1619931-27-9 |
MW: | 469.5 D |
ab 130,00 €
Artikelnummer: Cay19375-5
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
CAS | 417716-92-8 |
MW: | 426.9 D |
ab 43,00 €
Artikelnummer: Cay10010592-1
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the...
Schlagworte: | Tyrphostin AG-1296, 6,7-dimethoxy-2-phenyl-quinoxaline |
Anwendung: | PDGF receptor kinase inhibitor |
CAS | 146535-11-7 |
MW: | 266.3 D |
ab 38,00 €
Artikelnummer: BPS-40260
Active recombinant mouse PDGFRalpha (550-end) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is NM_011058.
Schlagworte: | CD140a, Pdgfr-2, AI115593, |
Anwendung: | Enzyme kinetics, inhibitor screening |
MW: | 89 kD |
862,00 €
Artikelnummer: Cay20213-1
SU 4312 is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 µM, respectively). It demonstrates IC50 values >100 µM at EGFR, HER2, and IGF-1R. SU 4312 has been shown to inhibit VEGF-dependent angiogenesis in a zebrafish assay (IC50 = 1.8 µM) without affecting normal...
Schlagworte: | NSC 86429, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one |
Anwendung: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
CAS | 5812-07-7 |
MW: | 264.3 D |
ab 43,00 €
Artikelnummer: Cay19923-1
Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl, with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form. Radotinib also inhibits platelet-derived growth factor receptors (PDGFRs) alpha...
Schlagworte: | IY-5511,... |
Anwendung: | Bcr-Abl tyrosine kinase & PDGFR inhibitor |
CAS | 926037-48-1 |
MW: | 530.5 D |
ab 43,00 €
Artikelnummer: Cay26174-1
c-Kit-IN-1 is a dual inhibitor of c-Kit and c-MET (IC50s = 50s = 50 = 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: Partially soluble. lambdamax: 250 nm. SMILES:...
Schlagworte: | N-[2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide |
Anwendung: | KIT / PDGFR inhibitor |
CAS | 1225278-16-9 |
MW: | 489.5 D |
ab 43,00 €
Artikelnummer: 97557.1
Human recombinant PDGFRA produced in E.coli is a single, non-glycosylated polypeptide chain containing 522 amino acids (24-524) and having a molecular mass of 58.4 kDa. The PDGFRA is fused to a 20 amino acid His-Tag at N-terminus. PDGFRa is a cell surface tyrosine kinase receptor for PDGF family members. PDGFRa...
Schlagworte: | Platelet-derived growth factor receptor alpha polypeptide, PDGFR2, PDGF-R-alpha, CD140 antigen-like family member A,... |
Anwendung: | Bioassay |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 58400 D |
ab 94,00 €