Zu "K04363" wurden 279 Artikel gefunden!
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![Anti-CD140a Antibody[APA5]](https://www.biomol.com/media/image/05/c8/89/E-AN009980P-25_200x200.jpg "Anti-CD140a Antibody[APA5]")
Anti-CD140a Antibody[APA5]
Artikelnummer: E-AN009980P.100
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a...
| Schlagworte: | Anti-Pdgfra, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth factor receptor alpha, Anti-Alpha... |
| Anwendung: | FCM |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
ab 20,00 €
NEU
![Anti-CD140a Antibody[APA5], Functional Grade](https://www.biomol.com/media/image/4a/cd/cf/E-AN009980-1_200x200.jpg "Anti-CD140a Antibody[APA5], Functional Grade")
Anti-CD140a Antibody[APA5], Functional Grade
Artikelnummer: E-AN009980.1
PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a...
| Schlagworte: | Anti-Pdgfra, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth factor receptor alpha, Anti-Alpha... |
| Anwendung: | FCM, FA, Block, Neut |
| Wirt: | Rat |
| Spezies-Reaktivität: | mouse |
ab 89,00 €
NEU
Anti-Recombinant PDGF Receptor alpha, clone C112987
Artikelnummer: E-AN303367L.100
Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an...
| Schlagworte: | Anti-PDGFRA, Anti-CD140a antigen, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth factor receptor 2,... |
| Anwendung: | WB, IHC, ICC/IF, FCM, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Anti-PDGFRalpha (5D1), monoclonal
Artikelnummer: ELK-EM1336.100
Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRalpha) and PDGF receptor beta (PDGFRbeta)....
| Schlagworte: | Anti-PDGFRA, Anti-CD140a antigen, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth factor receptor 2,... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
ab 173,00 €
N,N-dimethyl Sunitinib
Artikelnummer: Cay45148-1
A multi-kinase inhibitor and derivative of sunitinib, inhibits VEGFR1, VEGFR2, PDGFR, and c-Kit (IC50s = 0.013, 0.017, 0.005, and 0.04 µM, respectively), reduces the degradation of cartilage proteoglycan and the severity of arthritis in the K/BxN mouse model of rheumatoid arthritis at 40 mg/kg, reduces intratumoral...
| Schlagworte: | SU 11657,... |
| Anwendung: | Sunitinib derivative, multi-kinase inhibitor |
| CAS | 326914-17-4 |
| MW: | 370.43 D |
ab 439,00 €
Anti-Recombinant PDGFR-alpha, clone 4B4
Artikelnummer: E-AN300805L.100
PDGFRA(platelet derived growth factor receptor alpha) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer...
| Schlagworte: | Anti-PDGFRA, Anti-CD140a antigen, Anti-CD140 antigen-like family member A, Anti-Platelet-derived growth factor receptor 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 257,00 €
Lenvatinib
Artikelnummer: Cay19375-5
Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
| Schlagworte: | E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide |
| Anwendung: | VEGFR / FGFR / PDGFR inhibitor |
| CAS | 417716-92-8 |
| MW: | 426.9 D |
ab 51,00 €
AG-1296
Artikelnummer: Cay10010592-1
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the...
| Schlagworte: | Tyrphostin AG-1296, 6,7-dimethoxy-2-phenyl-quinoxaline |
| Anwendung: | PDGF receptor kinase inhibitor |
| CAS | 146535-11-7 |
| MW: | 266.3 D |
ab 44,00 €
SU 4312
Artikelnummer: Cay20213-1
SU 4312 is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 µM, respectively). It demonstrates IC50 values >100 µM at EGFR, HER2, and IGF-1R. SU 4312 has been shown to inhibit VEGF-dependent angiogenesis in a zebrafish assay (IC50 = 1.8 µM) without affecting normal...
| Schlagworte: | NSC 86429, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one |
| Anwendung: | Selective, cell-permeable VEGFR2 / PDGFR inhibitor |
| CAS | 5812-07-7 |
| MW: | 264.3 D |
ab 51,00 €
Anti-PDGFRA (CD140a)
Artikelnummer: NSJ-F50654-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PDGFRA is a tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell...
| Schlagworte: | Anti-PDGFR2, Anti-PDGFRA, Anti-CD140a, Anti-PDGFR-2, Anti-PDGFR-alpha, EC=2.7.10.1, Anti-PDGF-R-alpha, Anti-CD140a... |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Radotinib
Artikelnummer: Cay19923-1
Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl, with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form. Radotinib also inhibits platelet-derived growth factor receptors (PDGFRs) alpha...
| Schlagworte: | IY-5511,... |
| Anwendung: | Bcr-Abl tyrosine kinase & PDGFR inhibitor |
| CAS | 926037-48-1 |
| MW: | 530.5 D |
ab 51,00 €
c-Kit-IN-1
Artikelnummer: Cay26174-1
c-Kit-IN-1 is a dual inhibitor of c-Kit and c-MET (IC50s = 50s = 50 = 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: Partially soluble. lambdamax: 250 nm. SMILES:...
| Schlagworte: | N-[2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide |
| Anwendung: | KIT / PDGFR inhibitor |
| CAS | 1225278-16-9 |
| MW: | 489.5 D |
ab 51,00 €