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Anti-PDGFR alpha / PDGFRA, clone AAOE-16
Anti-PDGFR alpha / PDGFRA, clone AAOE-16

Artikelnummer: NSJ-RQ5478

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The PDGFRA gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a...
Schlagworte: Anti-CD140a, Anti-PDGFR2, Anti-PDGFRA, Anti-PDGFR-2, Anti-PDGFR-alpha, EC=2.7.10.1, Anti-PDGF-R-alpha, Anti-CD140a...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
755,00 €
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-10 %
Rabattaktion
Rat PDGFRa (Platelet Derived Growth Factor Receptor Alpha) ELISA Kit
Rat PDGFRa (Platelet Derived Growth Factor Receptor...

Artikelnummer: ELK-ELK5831.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PDGFRa. Next,...
Schlagworte: CD140a, Pdgfra, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140 antigen-like family member A, Platelet-derived growth factor...
Anwendung: ELISA
Spezies-Reaktivität: rat
365,00 € ab 328,50 €
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-10 %
Rabattaktion
Human PDGFRa (Platelet Derived Growth Factor Receptor Alpha) ELISA Kit
Human PDGFRa (Platelet Derived Growth Factor Receptor...

Artikelnummer: ELK-ELK2768.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDGFRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDGFRa....
Schlagworte: CD140a, PDGFR2, PDGFRA, PDGFR-2, PDGFR-alpha, EC=2.7.10.1, PDGF-R-alpha, CD140a antigen, CD140 antigen-like family member...
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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Anti-CD140a / PDGFRA (PE-Cyanine 7), clone 16A1
Anti-CD140a / PDGFRA (PE-Cyanine 7), clone 16A1

Artikelnummer: ARG43854.100

Protein function: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an...
Schlagworte: Anti-PDGFRA, Anti-PDGFR2, Anti-CD140a, Anti-CD140a, Anti-PDGFR-2, Anti-PDGFR-2, Anti-PDGFR-alpha, Anti-PDGFR-alpha,...
Anwendung: FC
Wirt: Mouse
Spezies-Reaktivität: human
696,00 €
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Seralutinib
Seralutinib

Artikelnummer: Cay37754-25

Seralutinib is an inhibitor of PDGFR, c-Kit, and colony stimulating factor 1 receptor (CSF1R). It inhibits PDGF-BB-induced phosphorylation of ERK in PDGFRalpha-dependent H1703 human lung epithelial cells, human pulmonary arterial smooth muscle cells (HPASMCs), which express PDGFRalpha and PDGFRbeta, and human lung...
Schlagworte: GB002, PK 10571, N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)-2-pyrazinyl]amino]ethyl]phenyl]-5-methyl-3-pyridinecarboxamide
Anwendung: PDGFR / c-Kit / CSF1R inhibitor
CAS 1619931-27-9
MW: 469.5 D
ab 130,00 €
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Lenvatinib
Lenvatinib

Artikelnummer: Cay19375-5

Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Schlagworte: E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
Anwendung: VEGFR / FGFR / PDGFR inhibitor
CAS 417716-92-8
MW: 426.9 D
ab 43,00 €
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AG-1296
AG-1296

Artikelnummer: Cay10010592-1

Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as PTK blockers. PTK inhibitors specific for platelet-derived growth factor (PDGF) receptor kinase could help in the...
Schlagworte: Tyrphostin AG-1296, 6,7-dimethoxy-2-phenyl-quinoxaline
Anwendung: PDGF receptor kinase inhibitor
CAS 146535-11-7
MW: 266.3 D
ab 38,00 €
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PDGFRa, active mouse recombinant protein
PDGFRa, active mouse recombinant protein

Artikelnummer: BPS-40260

Active recombinant mouse PDGFRalpha (550-end) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. The gene accession number is NM_011058.
Schlagworte: CD140a, Pdgfr-2, AI115593,
Anwendung: Enzyme kinetics, inhibitor screening
MW: 89 kD
862,00 €
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SU 4312
SU 4312

Artikelnummer: Cay20213-1

SU 4312 is a selective, cell-permeable inhibitor of VEGFR2 and PDGFR tyrosine kinases (IC50s = 0.8 and 19.4 µM, respectively). It demonstrates IC50 values >100 µM at EGFR, HER2, and IGF-1R. SU 4312 has been shown to inhibit VEGF-dependent angiogenesis in a zebrafish assay (IC50 = 1.8 µM) without affecting normal...
Schlagworte: NSC 86429, 3-[[4-(dimethylamino)phenyl]methylene]-1,3-dihydro-2H-indol-2-one
Anwendung: Selective, cell-permeable VEGFR2 / PDGFR inhibitor
CAS 5812-07-7
MW: 264.3 D
ab 43,00 €
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Radotinib
Radotinib

Artikelnummer: Cay19923-1

Radotinib is a selective second generation tyrosine kinase inhibitor that targets both the wild-type and mutant forms of Bcr-Abl, with an IC50 value of 30.6 nM in Ba/F3 human chronic myeloid leukemia cells expressing the wild-type form. Radotinib also inhibits platelet-derived growth factor receptors (PDGFRs) alpha...
Schlagworte: IY-5511,...
Anwendung: Bcr-Abl tyrosine kinase & PDGFR inhibitor
CAS 926037-48-1
MW: 530.5 D
ab 43,00 €
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c-Kit-IN-1
c-Kit-IN-1

Artikelnummer: Cay26174-1

c-Kit-IN-1 is a dual inhibitor of c-Kit and c-MET (IC50s = 50s = 50 = 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: Partially soluble. lambdamax: 250 nm. SMILES:...
Schlagworte: N-[2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide
Anwendung: KIT / PDGFR inhibitor
CAS 1225278-16-9
MW: 489.5 D
ab 43,00 €
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Platelet Derived Growth Factor Receptor, Alpha, His Tag, human recombinant (rHuPDGFRA-His)
Platelet Derived Growth Factor Receptor, Alpha, His Tag,...

Artikelnummer: 97557.1

Human recombinant PDGFRA produced in E.coli is a single, non-glycosylated polypeptide chain containing 522 amino acids (24-524) and having a molecular mass of 58.4 kDa. The PDGFRA is fused to a 20 amino acid His-Tag at N-terminus. PDGFRa is a cell surface tyrosine kinase receptor for PDGF family members. PDGFRa...
Schlagworte: Platelet-derived growth factor receptor alpha polypeptide, PDGFR2, PDGF-R-alpha, CD140 antigen-like family member A,...
Anwendung: Bioassay
Exprimiert in: E.coli
Ursprungsart: human
MW: 58400 D
ab 94,00 €
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