Zu "K04348" wurden 82 Artikel gefunden!
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Voclosporin
Artikelnummer: Cay39719-1
Voclosporin is an immunosuppressant and a derivative of cyclosporin A (Cay-12088). It binds to cyclophilin A (Kd = 15 nM) and inhibits calcineurin activity in isolated human whole blood (IC50 = 120 ng/ml). Voclosporin reduces the proliferation of, and production of IL-2, IFN-gamma, and TNF-alpha in, isolated...
| Schlagworte: | (E)-ISA247, trans-ISA 247, ISATX247, LX211, R-15424, 6-[(2S,3R,4R,6E)-3-hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic... |
| Anwendung: | Immunosuppressant, calcineurin inhibitor |
| CAS | 515814-01-4 |
| MW: | 1214.6 D |
ab 173,00 €
Human CaN (Calcineurin) ELISA Kit
Artikelnummer: ELK-ELK1882.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CaN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CaN. Next,...
| Schlagworte: | CALNA, CNA alpha, Calcineurin A alpha, CAM-PRP catalytic subunit, Protein phosphatase 3 catalytic subunit alpha,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse CaN (Calcineurin) ELISA Kit
Artikelnummer: ELK-ELK5257.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse CaN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse CaN. Next,...
| Schlagworte: | Calna, CNA alpha, Calcineurin A alpha, CAM-PRP catalytic subunit, Protein phosphatase 3 catalytic subunit alpha,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat CaN (Calcineurin) ELISA Kit
Artikelnummer: ELK-ELK5642.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat CaN. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat CaN. Next, Avidin...
| Schlagworte: | Calna, CNA alpha, Calcineurin A alpha, CAM-PRP catalytic subunit, Protein phosphatase 3 catalytic subunit alpha,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Anti-PPP3CA
Artikelnummer: ARG43929.50
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591). Many of the substrates contain a PxIxIT motif and/or a LxVP motif...
| Schlagworte: | Anti-CALNA, Anti-CAM-PRP catalytic subunit, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A... |
| Anwendung: | ELISA, FC, ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
520,00 €
Cyclosporin A
Artikelnummer: Cay12088-100
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of...
| Schlagworte: | NSC 290193 |
| Anwendung: | Immunosuppressant, Calcineurin inhibitor |
| CAS | 59865-13-3 |
| MW: | 1202.6 D |
ab 43,00 €
Cyclosporin A (Cyclosporine, Ciclosporin A, Ramhyphin A,...
Artikelnummer: LC-C-6000_1g
Soluble in DMSO at 100 mg/mL, soluble in ethanol at 200 mg/mL, very poorly soluble in water, maximum solubility in plain water is estimated to be about 5-10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | NSC 290193, cyclosporin A |
| Anwendung: | Immunosuppressant, Calcineurin inhibitor |
| CAS | 59865-13-3 |
| MW: | 1202,61 D |
ab 86,00 €
Cyclosporin A (5x100mg)
Artikelnummer: AG-CN2-0079-G001
Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No. AG-CN2-0025)) - Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells...
| Schlagworte: | Antibiotic S 7481F1, Ciclosporin A, CsA, Cyclosporine, NSC 290193, Ramihyphin A |
| Anwendung: | Immunsuppressant |
| CAS | 59865-13-3 |
| MW: | 1202,6 D |
ab 55,00 €
Isogarcinol
Artikelnummer: Cay21164-5
Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 µM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed...
| Schlagworte: | Cambogin,... |
| Anwendung: | Immunosuppressant, Calcineurin inhibitor |
| CAS | 71117-97-0 |
| MW: | 602.8 D |
ab 54,00 €
Ascomycin
Artikelnummer: LKT-A7208.5
FK506 analog, calcineurin inhibitor.
| Anwendung: | Antibiotic |
| CAS | 104987-12-4 |
| MW: | 792,01 D |
ab 101,00 €
Anti-PPP3CA
Artikelnummer: A300-907A
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. [The UniProt Consortium]
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-PPP3CA
Artikelnummer: A300-908A
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. [The UniProt Consortium]
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €