Zu "K04348" wurden 98 Artikel gefunden!
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Cyclosporin A
Artikelnummer: Cay12088-100
Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of...
| Schlagworte: | NSC 290193 |
| Anwendung: | Immunosuppressant, calcineurin inhibitor |
| CAS | 59865-13-3 |
| MW: | 1202.6 D |
ab 53,00 €
Cyclosporin A (5x100mg)
Artikelnummer: AG-CN2-0079-G001
Potent immunosuppressant (same as FK-506 (Prod. No. AG-CN2-0047) and rapamycin (Prod. No. AG-CN2-0025)) - Forms a complex with cyclophilin. Inhibits the activity of the calcium/calmodulin-dependent protein phosphatase 2B (PP2B, calcineurin). Prevents the dephosphorylation of nuclear factor of activated T cells...
| Schlagworte: | Antibiotic S 7481F1, Ciclosporin A, CsA, Cyclosporine, NSC 290193, Ramihyphin A |
| Anwendung: | Immunsuppressant |
| CAS | 59865-13-3 |
| MW: | 1202,6 D |
ab 55,00 €
Isogarcinol
Artikelnummer: Cay21164-5
Isogarcinol is a natural polyisoprenylated benzophenone first isolated from plant species in the genus Garcinia. It has immunosuppressant actions, inhibiting the protein phosphatase calcineurin (IC50 = 36 µM) and suppressing the proliferation of T cells. Oral administration of isogarcinol in mice decreases delayed...
| Schlagworte: | Cambogin,... |
| Anwendung: | Immunosuppressant, calcineurin inhibitor |
| CAS | 71117-97-0 |
| MW: | 602.8 D |
ab 60,00 €
Ascomycin
Artikelnummer: LKT-A7208.5
FK506 analog, calcineurin inhibitor.
| Anwendung: | Antibiotic |
| CAS | 104987-12-4 |
| MW: | 792,01 D |
ab 106,00 €
Anti-PPP3CA
Artikelnummer: A300-907A
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. [The UniProt Consortium]
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-PPP3CA
Artikelnummer: A300-908A
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. [The UniProt Consortium]
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-Calcineurin / PPP3CA
Artikelnummer: NSJ-R32200
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Calcineurin A is also known as PPP3CA. It is mapped to 4q24. Semsarian et al. (1999) and Musaro et al. (1999) independently showed that IGF1stimulates skeletal muscle hypertrophy and a switch to glycolytic metabolism by activating calcineurin A and inducing the...
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-PPP3CA (IHC)
Artikelnummer: IHC-00486
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates DNM1L, HSPB1 and SSH1. [The UniProt Consortium]
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-Calcineurin
Artikelnummer: NSJ-F51154-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1. Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase. Many...
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-PPP3CA
Artikelnummer: E-AB-14813.120
Protein phosphatase 3, catalytic subunit, alpha isozyme is a protein that in humans is encoded by thePPP3CA gene. Calcium-dependent, calmodulin-stimulated protein phosphatase. Many of the substrates contain a PxIxIT motif. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates...
| Schlagworte: | Anti-CALNA, Anti-PPP3CA, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-PPP3CC
Artikelnummer: NSJ-F40087-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation...
| Schlagworte: | Anti-CALNA3, Anti-PPP3CC, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calcineurin, testis-specific catalytic... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-PPP3CC
Artikelnummer: NSJ-F40178-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation...
| Schlagworte: | Anti-CALNA3, Anti-PPP3CC, EC=3.1.3.16, Anti-CAM-PRP catalytic subunit, Anti-Calcineurin, testis-specific catalytic... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €