Zu "K04345" wurden 141 Artikel gefunden!
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Anti-Recombinant PRKACA, clone 8A3
Artikelnummer: E-AN300927L.100
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free...
| Schlagworte: | Anti-PRKACA, Anti-cAMP-dependent protein kinase catalytic subunit alpha, Recombinant PRKACA Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-phospho-PKA C (Thr197) / PRKACA/PRKACB/PRKACG, clone...
Artikelnummer: NSJ-FY13272
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-PKA C (Thr197) antibody detects Protein kinase A catalytic subunit phosphorylated at threonine 197, encoded by PRKACA, PRKACB, and PRKACG. Protein kinase A catalytic subunit is the enzymatic...
| Schlagworte: | Anti-phospho-PRKACG, Anti-phospho-cAMP-dependent protein kinase catalytic subunit gamma, Phospho-PKA C (Thr197) Antibody /... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
PKA/PRKACA, His, Canine
Artikelnummer: GSC-Z04714-100
The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide variety of cellular processes including metabolism, cell growth, gene expression and apoptosis....
| Schlagworte: | PRKACA, cAMP-dependent protein kinase catalytic subunit alpha |
| Ursprungsart: | dog |
| MW: | 41.51 kD |
ab 457,00 €
H-89 (hydrochloride)
Artikelnummer: Cay10010556-10
Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM in standard...
| Schlagworte: | 5-Isoquinolinesulfonamide, Protein Kinase Inhibitor H-89,... |
| Anwendung: | PKA inhibitor |
| CAS | 130964-39-5 |
| MW: | 519.3 D |
ab 73,00 €
PKA Inhibitor (5-24) (trifluoroacetate salt)
Artikelnummer: Cay15996-1
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent...
| Schlagworte: | PKI (5-24), Protein Kinase A Inhibitor (5-24),... |
| Anwendung: | cAMP-dependent protein kinase (PKA) inhibitor |
| MW: | 2222.4 D |
ab 110,00 €
H89
Artikelnummer: LKT-H0003.1
Selective potent inhibitor of cAMP-dependent protein kinase (PKA).
| Schlagworte: | N-[2-[P-Bromocinnamylamino]-ethyl)-5-isoquinolinesulfonmide |
| Anwendung: | PKA inhibitor |
| CAS | 127243-85-0 |
| MW: | 446,36 D |
ab 77,00 €
8-bromo Cyclic AMP (sodium salt)
Artikelnummer: Cay14431-25
8-bromo Cyclic AMP is an activator of protein kinase A (PKA) with a half-maximal activation (Ka) value of 0.05 µM. It is selective for PKA over cGMP-dependent protein kinase (PKG, Ka = 5.8 µM) and is more resistant to hydrolysis by phosphodiesterases (PDEs) compared with cAMP (Cay-18820). 8-bromo Cyclic AMP inhibits...
| Schlagworte: | 8-bromo-cAMP, 8-Bromoadenosine 3',5'-cyclic monophosphate, 8-bromo-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium... |
| Anwendung: | cAMP analog, PKA activator |
| CAS | 76939-46-3 |
| MW: | 430.1 D |
ab 58,00 €
KT 5720
Artikelnummer: Cay10011011-50
Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. KT 5720 is one of a family of compounds synthesized by the fungus Nocardiopsis sp. It blocks PKA signaling through competitive...
| Schlagworte: | 2,3,9,10,11,12-hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzo... |
| Anwendung: | PKA inhibitor |
| CAS | 108068-98-0 |
| MW: | 537.6 D |
ab 122,00 €
Anti-PKA gamma (catalytic subunit)
Artikelnummer: ARG65764.100
Protein function: Phosphorylates a large number of substrates in the cytoplasm and the nucleus. [The UniProt Consortium]
| Schlagworte: | Anti-PRKACG, Anti-PKA C-gamma, EC=2.7.11.11, Anti-cAMP-dependent protein kinase catalytic subunit gamma |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
KT5720
Artikelnummer: LKT-K7600.100
A protein kinase inhibitor that has been shown to reduce enzyme activity in INF- alpha thereby creating a potential pathway to treat tumors.
| Anwendung: | Protein kinase inhibitor |
| CAS | 108068-98-0 |
| MW: | 537,23 D |
ab 406,00 €
Cyclic AMP
Artikelnummer: Cay18820-1
Cyclic AMP (cAMP) is a central second messenger in cell signaling, propagating signals from receptors to downstream pathways. It is generated from ATP by several adenylate cyclase enzymes, which are modulated by G protein-coupled receptors. cAMP activates protein kinase A and the exchange proteins activated by cAMP...
| Schlagworte: | Adenosine 3',5'-cyclic monophosphate, cAMP, Cyclic adenosine monophosphate, NSC 143670, NSC 94017, cyclic 3',5'-(hydrogen... |
| Anwendung: | PKA activator |
| CAS | 60-92-4 |
| MW: | 329.2 D |
ab 80,00 €
8-CPT-Cyclic AMP (sodium salt)
Artikelnummer: Cay12011-50
8-CPT-Cyclic AMP is a lipophilic activator of the cyclic-AMP- and cyclic-GMP-dependent protein kinases, PKA and PKG (Ka = 0.05 and 0.11 µM, respectively). 8-CPT-cAMP inhibits cyclic GMP-specific phosphodiesterase (PDE VA), cyclic GMP-inhibited phosphodiesterase (PDE III), and cyclic AMP-specific phosphodiesterase...
| Schlagworte: | 8-(p-Chlorophenylthio)-cAMP, 8-CPT-cAMP, 8-[(4-chlorophenyl)thio]-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium... |
| Anwendung: | PKA/PKG activator |
| CAS | 93882-12-3 |
| MW: | 493.8 D |
ab 85,00 €