Zu "K04345" wurden 101 Artikel gefunden!
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Malantide (trifluoroacetate salt)
Artikelnummer: Cay40150-1
Malantide is a synthetic peptide derived from the beta-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC. Upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity. Malantide displays an emission at 302 nm...
| Schlagworte: | L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-serylglycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-... |
| Anwendung: | Fluorescent PKA / PKC substrate |
| MW: | 1633.9 D |
ab 61,00 €
Human PRKACa (Protein Kinase, cAMP Dependent Catalytic...
Artikelnummer: ELK-ELK7535.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PRKACa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PRKACa....
| Schlagworte: | PKACA, PRKACA, PKA C-alpha, cAMP-dependent protein kinase catalytic subunit alpha |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Anti-phospho-PKAalpha cat (Ser338)
Artikelnummer: ELK-ES6739.100
This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free...
| Schlagworte: | Anti-phospho-PKACA, Anti-phospho-PRKACA, Anti-phospho-PKA C-alpha, Anti-phospho-cAMP-dependent protein kinase catalytic... |
| Anwendung: | IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Anti-PKAbeta cat
Artikelnummer: ELK-ES6743.100
The protein encoded by this gene is a member of the serine/threonine protein kinase family. The encoded protein is a catalytic subunit of cAMP (cyclic AMP)-dependent protein kinase, which mediates signalling though cAMP. cAMP signaling is important to a number of processes, including cell proliferaton and...
| Schlagworte: | Anti-PRKACB, Anti-PKA C-beta, Anti-cAMP-dependent protein kinase catalytic subunit beta, PKAbeta cat rabbit pAb |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 169,00 €
Anti-PKAgamma cat
Artikelnummer: ELK-ES6744.100
Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by...
| Schlagworte: | Anti-PRKACG, Anti-PKA C-gamma, EC=2.7.11.11, Anti-cAMP-dependent protein kinase catalytic subunit gamma, PKAgamma cat... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
H-89 (hydrochloride)
Artikelnummer: Cay10010556-10
Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM in standard...
| Schlagworte: | 5-Isoquinolinesulfonamide, Protein Kinase Inhibitor H-89,... |
| Anwendung: | PKA inhibitor |
| CAS | 130964-39-5 |
| MW: | 519.3 D |
ab 66,00 €
PKA Inhibitor (5-24) (trifluoroacetate salt)
Artikelnummer: Cay15996-1
PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (Ki = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent...
| Schlagworte: | PKI (5-24), Protein Kinase A Inhibitor (5-24),... |
| Anwendung: | cAMP-dependent protein kinase (PKA) inhibitor |
| MW: | 2222.4 D |
ab 98,00 €
H89
Artikelnummer: LKT-H0003.1
Selective potent inhibitor of cAMP-dependent protein kinase (PKA).
| Schlagworte: | N-[2-[P-Bromocinnamylamino]-ethyl)-5-isoquinolinesulfonmide |
| Anwendung: | PKA inhibitor |
| CAS | 127243-85-0 |
| MW: | 446,36 D |
ab 73,00 €
8-bromo Cyclic AMP (sodium salt)
Artikelnummer: Cay14431-25
8-bromo Cyclic AMP is an activator of protein kinase A (PKA) with a half-maximal activation (Ka) value of 0.05 µM. It is selective for PKA over cGMP-dependent protein kinase (PKG, Ka = 5.8 µM) and is more resistant to hydrolysis by phosphodiesterases (PDEs) compared with cAMP (Cay-18820). 8-bromo Cyclic AMP inhibits...
| Schlagworte: | 8-bromo-cAMP, 8-Bromoadenosine 3',5'-cyclic monophosphate, 8-bromo-cyclic 3',5'-(hydrogen phosphate)-adenosine, monosodium... |
| Anwendung: | cAMP analog, PKA activator |
| CAS | 76939-46-3 |
| MW: | 430.1 D |
ab 50,00 €
KT 5720
Artikelnummer: Cay10011011-50
Protein kinase A (PKA) regulates multiple signal transduction events via protein phosphorylation and is integral to all cellular responses involving the cyclic AMP second messenger system. KT 5720 is one of a family of compounds synthesized by the fungus Nocardiopsis sp. It blocks PKA signaling through competitive...
| Schlagworte: | 2,3,9,10,11,12-hexahydro-10S-hydroxy-9-methyl-1-oxo-9R,12S-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzo... |
| Anwendung: | PKA inhibitor |
| CAS | 108068-98-0 |
| MW: | 537.6 D |
ab 109,00 €
Anti-PKA gamma (catalytic subunit)
Artikelnummer: ARG65764.100
Protein function: Phosphorylates a large number of substrates in the cytoplasm and the nucleus. [The UniProt Consortium]
| Schlagworte: | Anti-PRKACG, Anti-PKA C-gamma, EC=2.7.11.11, Anti-cAMP-dependent protein kinase catalytic subunit gamma |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
KT5720
Artikelnummer: LKT-K7600.100
A protein kinase inhibitor that has been shown to reduce enzyme activity in INF- alpha thereby creating a potential pathway to treat tumors.
| Anwendung: | Protein kinase inhibitor |
| CAS | 108068-98-0 |
| MW: | 537,23 D |
ab 386,00 €