Zu "K04328" wurden 33 Artikel gefunden!
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CHO-K1/FFA2/Galpha15 Stable Cell Line
Artikelnummer: GSC-M00437
Recombinant CHO-K1 cells stably overexpress human free fatty acid receptor 2 (FFA2) on the surface and contain high levels of G protein Galphaq and Galphai to couple with the receptor in downstream signaling pathways.
| Schlagworte: | FFAR2, Free fatty acid receptor 2, G-protein coupled receptor 43 |
11.424,00 €
(±)-4-CMTB
Artikelnummer: Cay29680-5
(±)-4-CMTB is a positive allosteric modulator of free fatty acid receptor 2 (FFAR2/GPR43) with an EC50 value of 0.42 µM for [35S]GTPgammaS binding to 293 T-REx cell membranes expressing the human receptor. It selectively induces ERK1/2 phosphorylation in 293 T-REx cells expressing human FFAR2, but not FFAR1 or...
| Schlagworte: | 4-chloro-alpha-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide |
| Anwendung: | FFAR2/GPR43 positive allosteric modulator |
| CAS | 300851-67-6 |
| MW: | 294.8 D |
ab 174,00 €
Anti-FFAR2 / GPR43
Artikelnummer: ARG66475.100
Protein function: G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate,...
| Schlagworte: | Anti-FFA2, Anti-FFAR2, Anti-Free fatty acid receptor 2, Anti-G-protein coupled receptor 43 |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
GLPG0974
Artikelnummer: Cay28108-1
GLPG0974 is an antagonist of free fatty acid receptor 2 (FFAR2/GPR43, IC50 = 9 nM). It is selective for FFAR2 over FFAR3 at concentrations up to 30 µM and over a panel of 55 receptors, ion channels, and transporters at 10 µM. GLPG0974 inhibits acetate-induced migration of isolated human neutrophils in buffer or...
| Schlagworte: | 4-[[[(2R)-1-(benzo[b]thien-3-ylcarbonyl)-2-methyl-2-azetidinyl]carbonyl][(3-chlorophenyl)methyl]amino]-butanoic acid |
| Anwendung: | FFAR2/GPR43 antagonist |
| CAS | 1391076-61-1 |
| MW: | 485 D |
ab 93,00 €
Propionic Acid-d5
Artikelnummer: Cay39159-10
Propionic acid-d5 is intended for use as an internal standard for the quantification of propionic acid by GC- or LC-MS. Propionic acid is a short-chain fatty acid. It is produced predominately by bacterial fermentation of dietary fiber in the colon but is also found in various dairy products such as yogurt....
| Schlagworte: | Propanoic Acid-d5, Propionate-d5, propanoic-d5 acid |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, FFAR2/FFAR3 agonist |
| CAS | 60153-92-6 |
| MW: | 79.1 D |
ab 151,00 €
Anti-FFAR2 (GPR43) (Internal)
Artikelnummer: Cay15727-1
GPR43 is a G protein-coupled receptor activated by short chain fatty acids (SCFAs). Several SCFAs have the potential to bind and activate GPR43, including acetate, formate, propionate, and butyrate. GPR43 couples through the Pertussis toxin-sensitive Gi/o and the pertussis toxin-insensitive Gq protein families and...
| Schlagworte: | Anti-FFA2, Anti-FFAR2, Anti-Free fatty acid receptor 2, Anti-Free fatty acid receptor 2, Anti-G-protein coupled receptor... |
| Anwendung: | FC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
468,00 €
Mouse FFAR2 (Free Fatty Acid Receptor 2) ELISA Kit
Artikelnummer: ELK-ELK7062.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FFAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FFAR2. Next,...
| Schlagworte: | Ffar2, Gpr43, Free fatty acid receptor 2, G-protein coupled receptor 43, Leukocyte-specific STAT-induced GPCR |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
GLPG0974
Artikelnummer: TGM-T15388-10mg
Description: GLPG0974 is an antagonist of FFA2/GPR43 with IC50 of 9 nM. Target: GPR. Smiles: C[C@@]1(CCN1C(=O)c1csc2ccccc12)C(=O)N(CCCC(O)=O)Cc1cccc(Cl)c1. References: Pizzonero M, et al. Discovery and optimization of an azetidine chemical series as a free fatty acid receptor 2 (FFA2) antagonist: from hit to clinic....
| Schlagworte: | GLPG-0974 |
| Anwendung: | FFAR2/GPR43 antagonist |
| CAS | 1391076-61-1 |
| MW: | 484.99 D |
ab 48,00 €
4-CMTB
Artikelnummer: TGM-T8642-100mg
Description: 4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38). Target: GPR. Smiles: CC(C)C(C(=O)Nc1nccs1)c1ccc(Cl)cc1. References: Milligan G, Stoddart LA, Smith NJ. Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3. Br J...
| Anwendung: | FFAR2/GPR43 positive allosteric modulator |
| CAS | 300851-67-6 |
| MW: | 294.8 D |
ab 39,00 €
Propionicacid-d5
Artikelnummer: TGM-TMIJ-0052-1mg
Description: Propionicacid-d5 is a deuterated compound of Propionicacid. Propionicacid has a CAS number of 79-09-4. Propionic acid (PA) is widely used as an antifungal agent in food. It is present naturally at low levels in dairy products and occurs ubiquitously, together with other short-chain fatty acids (SCFA),...
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, FFAR2/FFAR3 agonist |
| CAS | 60153-92-6 |
| MW: | 79.11 D |
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NEU
Human FFAR2 (Free Fatty Acid Receptor 2) ELISA Kit
Artikelnummer: G-AEKE03828.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FFAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FFAR2. Next,...
| Schlagworte: | FFAR2, Free fatty acid receptor 2, G-protein coupled receptor 43 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
694,00 €
NEU
Mouse FFAR2 (Free Fatty Acid Receptor 2) ELISA (Small...
Artikelnummer: G-AEKE10239.96
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse FFAR2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse FFAR2. Next,...
| Schlagworte: | Ffar2, Free fatty acid receptor 2, G-protein coupled receptor 43, Leukocyte-specific STAT-induced GPCR |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
694,00 €