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Zu "K04322" wurden 42 Artikel gefunden!
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Artikelnummer: ELK-ELK3943.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human CYSLTR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human CYSLTR1....
Schlagworte: | CYSLT1, CysLTR1, CYSLTR1, HMTMF81, LTD4 receptor, G-protein coupled receptor HG55, Cysteinyl leukotriene receptor 1,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: AG-CR1-0021-M005
Selective leukotriene LTD4 receptor antagonist, Potent MRP1 inhibitor, Antinociceptive.
Anwendung: | LTD4 receptor antagonist, MRP1 inhibitor |
CAS | 115104-28-4 |
MW: | 514,1 D |
ab 55,00 €
Artikelnummer: Cay10008319-10
Pranlukast is an orally bioavailable cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50s = 4.3-7.2 nM in radioligand binding assays). It is selective for the CysLT1 receptor over the CysLT2 receptor (IC50 = 3,620 nM for the human receptor). Pranlukast inhibits mucus secretion induced by leukotriene D4 (LTD4,...
Schlagworte: | ONO-1078, ONO-RS-411, N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-benzamide |
Anwendung: | CysLT1 receptor antagonist |
CAS | 103177-37-3 |
MW: | 481.5 D |
ab 26,00 €
Artikelnummer: Cay11948-1
MN-001 is an anti-inflammatory agent. In vivo, MN-001 (10, 30, and 50 mg/kg) reduces the frequency of bladder voids, increases the intercontractile interval, and decreases the number of non-voiding contractions in a rat model of bladder hyperactivity induced by ovalbumin-induced mast cell stimulation.Formal Name:...
Schlagworte: | KCA 757, Tipelukast, 4-[6-acetyl-3-[3-[(4-acetyl-3-hydroxy-2-propylphenyl)thio]propoxy]-2-propylphenoxy]-butanoic acid |
Anwendung: | Antiasthmatic, leukotriene antagonist |
CAS | 125961-82-2 |
MW: | 530.7 D |
ab 96,00 €
Artikelnummer: Cay70710-5
LY171883 is a selective, potent, orally active antagonist of the leukotriene D4 receptor. Dissociation constants (KB) for LY171883 on guinea pig ileum and parenchyma are 0.07 and 0.34 µM, respectively. LY171883 is an inhibitor of phosphodiesterase obtained from human polymorphonuclear leukocytes (IC50 of 22.6 µM)...
Schlagworte: | 1-[2-hydroxy-3-propyl-4-[4-(1H-tetrazol-5-yl)butoxy]phenyl]-ethanone |
Anwendung: | CysLTR1 antagonist |
CAS | 88107-10-2 |
MW: | 318.4 D |
ab 54,00 €
Artikelnummer: BPS-27211
LY171883 is a PDE inhibitor and a selective, potent inhibitor of the leukotriene D4 receptor. Also, LY171883 binds to the PPAR nuclear receptor at 50-100 µM and induces adipogenesis in cultured NIH3T3 fibroblasts.
Anwendung: | PDE inhibitor, CysLTR1 antagonist |
MW: | 318.4 D |
318,00 €
Artikelnummer: G-HUFI02379.96
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
641,00 €
Artikelnummer: LKT-M5756.10
A cysteinyl leukotriene receptor antagonist with anti-inflammatory effects. In rat colitis it has been shown to increase prostaglandin E(2) production and decrease the cyclogenase-2 protein expression.
Anwendung: | Cysteinyl leukotriene receptor antagonist |
CAS | 151767-02-1 |
MW: | 608,17 D |
ab 108,00 €
Artikelnummer: Cay22180-1
Montelukast-d6 (sodium salt) is intended for use as an internal standard for the quantification of montelukast (sodium salt) (Cay-10008318) by GC- or LC-MS. Montelukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor). It is selective...
Schlagworte: | MK-476-d6,... |
Anwendung: | GC-MS, LC-MS, Internal standard, Leukotriene receptor antagonist |
CAS | 2673270-26-1 |
MW: | 614.2 D |
ab 229,00 €
Artikelnummer: Cay22374-1
Dihydro montelukast is a potential impurity found in commercial montelukast preparations. Montelukast (sodium salt) (Cay-10008318) is a potent and selective cysteinyl leukotriene 1 (CysLT1) receptor antagonist. Formulations containing montelukast are used for the treatment of asthma as well as for the symptoms...
Schlagworte: | 1-[[[(1R)-1-[3-[2-(7-chloro-2-quinolinyl)ethyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-cyclopropa... |
Anwendung: | Impurity |
CAS | 142147-67-9 |
MW: | 588.2 D |
ab 130,00 €
Artikelnummer: Cay28709-1
Pranlukast-d4 is intended for use as an internal standard for the quantification of pranlukast (Cay-10008319) by GC- or LC-MS. Pranlukast is an orally bioavailable cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50s = 4.3-7.2 nM in radioligand binding assays). It is selective for the CysLT1 receptor over the...
Schlagworte: | N-[4-oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4-(4-phenylbutoxy)-benzamide-d4 |
Anwendung: | GC-MS, LC-MS, internal standard, CysLT1 receptor antagonist |
CAS | 2713172-43-9 |
MW: | 485.5 D |
530,00 €
Artikelnummer: G-HUES00589.96
ELISA Type: CLIA. Sensitivity: 37.5 pg/mL. Range: 62.5--4000 pg/mL. Protein function: Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to...
Schlagworte: | CYSLT1, CysLTR1, HMTMF81, CYSLTR1, LTD4 receptor, G-protein coupled receptor HG55, Cysteinyl leukotriene receptor 1,... |
Anwendung: | CLIA |
Spezies-Reaktivität: | human |
694,00 €