Zu "K04306" wurden 20 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
ML-290
Artikelnummer: Cay21134-1
ML-290 is an allosteric agonist of relaxin family peptide receptor 1 (RXFP1, EC50 = 0.094 µM for the human receptor in a cAMP produciton assay). It is selective for RXFP1 over RXFP2 (EC50 = 1.5 µM). ML-90 (250 nM) induces expression of VEGF in THP-1 cells expressing human RXFP1. It stimulates cAMP release from...
| Schlagworte: | RXFP1 Agonist 8, 2-[[2-(1-methylethoxy)benzoyl]amino]-N-[3-[(trifluoromethyl)sulfonyl]phenyl]-benzamide |
| Anwendung: | RXFP1 agonist |
| CAS | 1482500-76-4 |
| MW: | 506.5 D |
ab 57,00 €
AZD 5462
Artikelnummer: Cay40956-1
AZD 5462 is an agonist of relaxin family peptide receptor 1 (RXFP1). It induces cAMP mobilization in HEK293 cells expressing the human RXFP1 (EC50 = 15.85 nM). AZD 5462 increases heart rate and mean arterial blood pressure (MABP) in rats. It increases left ventricular ejection fraction (LVEF) in a cynomolgus monkey...
| Schlagworte: | cis-4-[2-fluoro-4-methoxy-5-[[[(1S,2R,3S,4R)-3-[[[(1-methylcyclobutyl)methyl]amino]carbonyl]bicyclo[2.2.1]hept-2-yl]amino]... |
| Anwendung: | RXFP1 agonist |
| CAS | 2787501-83-9 |
| MW: | 544.7 D |
ab 197,00 €
Human GPCR LGR7 / Relaxin R1 ELISA Kit
Artikelnummer: G-HUFI02831.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-RXFP1
Artikelnummer: ATA-HPA027067.100
Protein function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. [The UniProt...
| Schlagworte: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
AZD5462
Artikelnummer: TGM-T63838-100mg
Description: AZD5462 is a potent orally available relaxin receptor RXFP1 agonist for the study of heart failure and cancer. Target: RXFP receptor. Smiles: C(NCC1(C)CCC1)(=O)[C@@H]2[C@H](NC(=O)C3=C(OC)C=C(F)C(O[C@H]4CC[C@](C(O)=O)(C)CC4)=C3)[C@@]5(C[C@]2(CC5)[H])[H]. References: Granberg Kenneth Lars, et al....
| Anwendung: | RXFP1 agonist |
| CAS | 2787501-83-9 |
| MW: | 544.65 D |
ab 352,00 €
Nanodisc Human RXFP1 Protein
Artikelnummer: G-HDFP448.10
Protein function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. [The UniProt...
| Schlagworte: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.693,00 €
Nanodisc Human RXFP1-Strep Protein
Artikelnummer: G-HDFP1181.10
Protein function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. [The UniProt...
| Schlagworte: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.605,00 €
LGR7, Human, Real Time PCR Primer Set
Artikelnummer: VHPS-5280
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Anwendung: | RNA quantification |
45,00 €
Lgr7, Mouse leucine-rich repeat-containing G...
Artikelnummer: VMPS-3488
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Rxfp1, Gm1018, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Anwendung: | RNA quantification |
45,00 €
Anti-RXFP1, CT (RXFP1, LGR7, Relaxin receptor 1,...
Artikelnummer: 041344.200
Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. Applications: Suitable for use in...
| Schlagworte: | Anti-LGR7, Anti-RXFP1, Anti-Relaxin receptor 1, Anti-Relaxin family peptide receptor 1, Anti-Leucine-rich... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Mouse RXFP1 (Relaxin/Insulin Like Family Peptide Receptor...
Artikelnummer: G-MOFI01456.96
Mouse RXFP1 (Relaxin/Insulin Like Family Peptide Receptor 1) ELISA Kit from Assay Genie is a pre-coated immunoassay with a high sensitivity and broad range and has been designed to measure Mouse RXFP1 (Relaxin/Insulin Like Family Peptide Receptor 1) in serum, plasma & cell culture supernatant samples. The Mouse...
| Schlagworte: | Rxfp1, Gm1018, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
RXFP1 PrEST Antigen
Artikelnummer: ATA-APrEST72778.100
Protein function: Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP. [The UniProt...
| Schlagworte: | LGR7, RXFP1, Relaxin receptor 1, Relaxin family peptide receptor 1, Leucine-rich repeat-containing G-protein coupled... |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
264,00 €