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Zu "K04296" wurden 25 Artikel gefunden!
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Artikelnummer: Cay17620-1
CP 105,696 is an antagonist of the leukotriene B4 (LTB4) receptor (IC50 = 8.42 nM for the high-affinity receptor in human neutrophils). It inhibits chemotaxis induced by LTB4 (Cay-20110) in isolated human neutrophils (IC50 = 5 nM) and LTB4-induced calcium mobilization in isolated human monocytes (IC50 = 940 nM). CP...
| Schlagworte: | 1-[(3S,4R)-3-([1,1'-biphenyl]-4-ylmethyl)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-7-yl]-cyclopentanecarboxylic acid |
| Anwendung: | LTB4 receptor antagonist |
| CAS | 158081-99-3 |
| MW: | 428.5 D |
ab 41,00 €
Artikelnummer: Cay100019-1
The leukotriene B4 receptor 1 (BLT1 receptor), cloned from HL-60 human leukemia cells, has 352 amino acids and seven putative membrane-spanning domains. The primary structure of the receptor is identical to that of a putative purinoceptor, P2Y7, which binds to micromolar concentrations of ATP. Northern blotting...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-LTB4-R 1, Anti-P2Y... |
| Anwendung: | CF, FC, IHC (paraffin), WB |
| Wirt: | Rabbit |
468,00 €
Artikelnummer: ARG22450.50
Protein function: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-P2Y purinoceptor 7, Anti-Leukotriene B4 receptor 1,... |
| Anwendung: | IHC (frozen), FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: ARG22532.100
Protein function: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-P2Y purinoceptor 7, Anti-Leukotriene B4 receptor 1,... |
| Anwendung: | IHC (frozen), FC, ICC, IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Artikelnummer: Cay120111-1
The human BLT1 receptor is a G protein-coupled receptor that mediates the proinflammatory effects of leukotriene B4 (LTB4). Northern blotting reveals that the BLT1 receptor is highly expressed in leukocytes, U937 cells, and to a much lower extent in spleen and thymus. Sheep lung membranes have also been identified...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-LTB4-R 1, Anti-P2Y... |
| Anwendung: | FC, IF, IHC (frozen) |
| Wirt: | Mouse |
468,00 €
Artikelnummer: G-HUFI00412.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Artikelnummer: G-MOFI00181.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Artikelnummer: ATA-HPA003873.100
Protein function: Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-P2Y purinoceptor 7, Anti-Leukotriene B4 receptor 1,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: Cay120114-1
The leukotriene B4 receptor 1 (BLT1 receptor), cloned from HL-60 human leukemia cells, has 352 amino acids and seven putative membrane-spanning domains. The primary structure of the receptor is identical to that of a putative purinoceptor, P2Y7, which binds to micromolar concentrations of ATP. Northern blotting...
| Schlagworte: | Anti-BLT, Anti-P2Y7, Anti-P2Y7, Anti-LTB4R, Anti-LTB4-R1, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-LTB4-R 1, Anti-P2Y... |
| Anwendung: | FC, ICC, IHC, WB |
| Wirt: | Rabbit |
468,00 €
Artikelnummer: Cay30455-100
BLT1 is a high-affinity G protein-coupled receptor for leukotriene B4 (LTB4) with roles in the pathogenesis of various inflammatory and immune diseases. It is expressed in most immune cells, including neutrophils, macrophages, eosinophils, and T cells, as well as certain non-immune cells, such as endothelial cells,...
| Schlagworte: | Anti-Bltr, Anti-Ltb4r, Anti-LTB4-R1, Anti-LTB4-R1, Anti-LTB4-R 1, Anti-LTB4-R 1, Anti-Leukotriene B4 receptor 1,... |
| Anwendung: | FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
468,00 €
Artikelnummer: TGM-T15002-10mg
Description: CP-105696 is a potent and selective leukotriene B4 (LTB4) receptor antagonist used to study allograft rejection. Target: LTR. Smiles: O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)C1(CCCC1)C(O)=O. References: Weringer EJ, et al. Antagonizing leukotriene B4 receptors delays cardiac allograft rejection...
| Schlagworte: | Pfizer 105696 |
| Anwendung: | LTB4 receptor antagonist |
| CAS | 158081-99-3 |
| MW: | 428.52 D |
ab 80,00 €
NEU
Artikelnummer: GSC-M00435
The dihydroxy-leukotriene, leukotriene B4 (LTB4) is a member of the G protein-coupled receptor (GPCR) family, in a subfamily of GPCRs that includes receptors for chemokines and other chemotactic factors. Recently, a second, lower affinity receptor for LTB4 (BLT2) has also been cloned, with broader ligand specificity...
| Schlagworte: | LTB4R, P2Y purinoceptor 7, Leukotriene B4 receptor 1, G-protein coupled receptor 16, Chemoattractant receptor-like 1 |
11.424,00 €